Clinical Outcomes of Hypertonic Saline vs Mannitol Treatment Among Children With Traumatic Brain Injury

Importance: The use of hypertonic saline (HTS) vs mannitol in the control of elevated intracranial pressure (ICP) secondary to neurotrauma is debated. Objective: To compare mortality and functional outcomes of treatment with 3% HTS vs 20% mannitol among children with moderate to severe traumatic bra...

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Autores principales: Shu‐Ling Chong, Yanan Zhu, Quan Wang, Paula Caporal, Juan D. Roa, Freddy Israel Pantoja Chamorro, Thelma Elvira Terán Miranda, Hongxing Dang, Chin Seng Gan, Qalab Abbas, Ivan J. Ardila, Mohannad Antar, Jesús Domínguez-Rojas, María Miñambres Rodríguez, Natalia Zita Watzlawik, Natalia Elizabeth Gómez Arriola, Adriana Yock‐Corrales, Rubén Eduardo Lasso Palomino, Ming Mei Xiu, Jacqueline Soo May Ong, Hiroshi Kurosawa, Gabriela Aparicio, Chun‐Feng Liu, Rujipat Samransamruajkit, Juan Camilo Jaramillo-Bustamante, Nattachai Anantasit, Yek Kee Chor, Deborah M. Turina, Pei Chuen Lee, Marisol Fonseca Flores, J. Pilar Orive, Jing Wen, Sebastián González‐Dambrauskas, Jan Hau Lee, Pediatric Acute and Critical Care Medicine in Asia Network (PACCMAN) and the Red Colaborativa Pediátrica de Latinoamérica (LARed), Yasser Kazzaz, Jian Ji, Suyun Qian, Lijia Fan, Olive Pei Ee Lee, Soo Lin Chuah, Kai You, Tao Zhang, Deiby Lasso Noguera, Esteban Cerón, Andrea Leal Barceló, Susana Reyes, Cesia J Ortega Ocas
Formato: Artículo
Lenguaje:inglés
Publicado: 2025
Materias:
Medicine
Glasgow Coma Scale
Hypertonic saline
Traumatic brain injury
Pediatrics
Intensive care
Anesthesia
Intensive care medicine
Psychiatry
Brain Injuries, Traumatic complications
Brain Injuries, Traumatic drug therapy
Brain Injuries, Traumatic mortality
Adolescent
Asia epidemiology
Child
Child, Preschool
Diuretics, Osmotic therapeutic use
Europe
Female
Humans
Infant
Latin America
Male
Mannitol therapeutic use
Prospective Studies
Saline Solution, Hypertonic therapeutic use
Treatment Outcome
Intracranial Hypertension drug therapy
Intracranial Hypertension etiology
Health Sciences Medicine Neurology Traumatic Brain Injury and Neurovascular Disturbances
Health Sciences Medicine Critical Care and Intensive Care Medicine Trauma, Hemostasis, Coagulopathy, Resuscitation
Health Sciences Medicine Emergency Medicine Cardiac Arrest and Resuscitation
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