Influence of Hyperthyroidism on the Rate of Ethanol Metabolism in Man

The rate of ethanol metabolism was studied in 3 hyperthyroidism patients without therapy and in 2 after 1 week of treatment with propylthiouracil and reserpine. The rate of ethanol metabolism (mg/kg/h +/- SEM) was 386 +/- 57 in the 3 hyperthyroid patients, 184.5 +/- 2.5 in the 2 treated patients and...

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Guardado en:
Autores principales: G Ugarte, Tamara Peresa
Formato: Artículo
Lenguaje:inglés
Publicado: 1978
Materias:
Euthyroid
Propylthiouracil
Ethanol
Metabolism
Internal medicine
Endocrinology
Reserpine
Medicine
Ethanol metabolism
Antithyroid agent
Chemistry
Thyroid
Biochemistry
Graves' disease
Adult
Ethanol administration & dosage
Ethanol blood
Female
Humans
Hyperthyroidism drug therapy
Hyperthyroidism metabolism
Propylthiouracil therapeutic use
Reserpine therapeutic use
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry Eicosanoids and Hypertension Pharmacology
Health Sciences Medicine Physiology Diet and metabolism studies
Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment
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Sumario:The rate of ethanol metabolism was studied in 3 hyperthyroidism patients without therapy and in 2 after 1 week of treatment with propylthiouracil and reserpine. The rate of ethanol metabolism (mg/kg/h +/- SEM) was 386 +/- 57 in the 3 hyperthyroid patients, 184.5 +/- 2.5 in the 2 treated patients and 159 +/- 15 in 12 euthyroid non-alcoholic subjects. The results suggest that hyperthyroidism markedly increases ethanol metabolism.

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