Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease
Aspergillosis is a disease caused by the filamentous fungus Aspergillus spp. with a spectrum of clinical presentation that includes invasive and noninvasive forms. The invasive clinical presentation of aspergillosis most frequently affects people with compromised immune systems. In patients with onc...
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| author | Jorge Alberto Cortés Diego Andrés Rodríguez Lugo Martha Carolina Valderrama-Ríos Ricardo Rabagliati Domênico Capone Carlos Álvarez Fabio Varón-Vega Laura Cristina Nócua-Báez Cándida Díaz‐Brochero Leonardo Enciso-Olivera Sonia Isabel Cuervo Luis Thompson Dora Corzo-León Luis E. Cuéllar Erika Paola Vergara Fernando Riera Patricia Cornejo‐Juárez Rita Rojas Beatriz L. Gómez Adriana Marcela Celis Ramírez José Luis Sandoval‐Gutiérrez Mauricio Sarmiento Diana Lorena Ochoa Márcio Nucci |
| author_browse | Adriana Marcela Celis Ramírez Beatriz L. Gómez Carlos Álvarez Cándida Díaz‐Brochero Diana Lorena Ochoa Diego Andrés Rodríguez Lugo Domênico Capone Dora Corzo-León Erika Paola Vergara Fabio Varón-Vega Fernando Riera Jorge Alberto Cortés José Luis Sandoval‐Gutiérrez Laura Cristina Nócua-Báez Leonardo Enciso-Olivera Luis E. Cuéllar Luis Thompson Martha Carolina Valderrama-Ríos Mauricio Sarmiento Márcio Nucci Patricia Cornejo‐Juárez Ricardo Rabagliati Rita Rojas Sonia Isabel Cuervo |
| author_facet | Jorge Alberto Cortés Diego Andrés Rodríguez Lugo Martha Carolina Valderrama-Ríos Ricardo Rabagliati Domênico Capone Carlos Álvarez Fabio Varón-Vega Laura Cristina Nócua-Báez Cándida Díaz‐Brochero Leonardo Enciso-Olivera Sonia Isabel Cuervo Luis Thompson Dora Corzo-León Luis E. Cuéllar Erika Paola Vergara Fernando Riera Patricia Cornejo‐Juárez Rita Rojas Beatriz L. Gómez Adriana Marcela Celis Ramírez José Luis Sandoval‐Gutiérrez Mauricio Sarmiento Diana Lorena Ochoa Márcio Nucci |
| author_sort | Jorge Alberto Cortés |
| collection | Producción científica |
| description | Aspergillosis is a disease caused by the filamentous fungus Aspergillus spp. with a spectrum of clinical presentation that includes invasive and noninvasive forms. The invasive clinical presentation of aspergillosis most frequently affects people with compromised immune systems. In patients with oncohematologic pathology, invasive lung aspergillosis is a significant opportunistic mycosis, because it occurs frequently and has a major impact on morbidity, mortality, and high costs. The global problem of antimicrobial resistance, to which improper use of antifungals contributes, has put Aspergilus spp. in the spotlight, so it is important to generate guidelines for guidance in the proper use of antifungals in the management of invasive lung aspergillosis, to obtain better clinical outcomes and promote rational use of antifungals. This guideline contains recommendations for diagnosing and treating invasive lung aspergillosis in patients with oncohematologic disease, based on evidence and defined through a participatory process of expert consensus, for the Latin American context. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/759 |
| institution | UPeU |
| language | English |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/7592026-10-30T16:14:49ZEvidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic diseaseJorge Alberto CortésDiego Andrés Rodríguez LugoMartha Carolina Valderrama-RíosRicardo RabagliatiDomênico CaponeCarlos ÁlvarezFabio Varón-VegaLaura Cristina Nócua-BáezCándida Díaz‐BrocheroLeonardo Enciso-OliveraSonia Isabel CuervoLuis ThompsonDora Corzo-LeónLuis E. CuéllarErika Paola VergaraFernando RieraPatricia Cornejo‐JuárezRita RojasBeatriz L. GómezAdriana Marcela Celis RamírezJosé Luis Sandoval‐GutiérrezMauricio SarmientoDiana Lorena OchoaMárcio NucciAspergillosisContext (archaeology)GuidelineIntensive care medicineMedicineDiseaseImmunologyPathologyBiologyPaleontologyAspergillosisContext (archaeology)GuidelineIntensive care medicineMedicineDiseaseImmunologyPathologyBiologyAntifungal Agents therapeutic useAntifungal Agents therapeutic useAntifungal Agents therapeutic useAntifungal Agents therapeutic useAntifungal Agents therapeutic useHumansHumansHumansHumansHumansImmunocompromised HostImmunocompromised HostImmunocompromised HostImmunocompromised HostImmunocompromised HostEvidence-Based MedicineEvidence-Based MedicineEvidence-Based MedicineEvidence-Based Medicine standardsEvidence-Based Medicine standardsHematologic Neoplasms complicationsHematologic Neoplasms complicationsHematologic Neoplasms complicationsHematologic Neoplasms complicationsHematologic Neoplasms complicationsHematologic Neoplasms immunologyHematologic Neoplasms immunologyInvasive Pulmonary Aspergillosis diagnosisInvasive Pulmonary Aspergillosis diagnosisInvasive Pulmonary Aspergillosis diagnosisInvasive Pulmonary Aspergillosis diagnosisInvasive Pulmonary Aspergillosis diagnosisInvasive Pulmonary Aspergillosis drug therapyInvasive Pulmonary Aspergillosis drug therapyInvasive Pulmonary Aspergillosis drug therapyInvasive Pulmonary Aspergillosis drug therapyInvasive Pulmonary Aspergillosis drug therapyInvasive Pulmonary Aspergillosis immunologyInvasive Pulmonary Aspergillosis immunologyInvasive Pulmonary Aspergillosis microbiologyInvasive Pulmonary Aspergillosis microbiologyHealth Sciences Medicine Infectious Diseases Antifungal resistance and susceptibilityHealth Sciences Medicine Epidemiology Fungal Infections and StudiesHealth Sciences Veterinary Small Animals Infectious Diseases and MycologyAspergillosis is a disease caused by the filamentous fungus Aspergillus spp. with a spectrum of clinical presentation that includes invasive and noninvasive forms. The invasive clinical presentation of aspergillosis most frequently affects people with compromised immune systems. In patients with oncohematologic pathology, invasive lung aspergillosis is a significant opportunistic mycosis, because it occurs frequently and has a major impact on morbidity, mortality, and high costs. The global problem of antimicrobial resistance, to which improper use of antifungals contributes, has put Aspergilus spp. in the spotlight, so it is important to generate guidelines for guidance in the proper use of antifungals in the management of invasive lung aspergillosis, to obtain better clinical outcomes and promote rational use of antifungals. This guideline contains recommendations for diagnosing and treating invasive lung aspergillosis in patients with oncohematologic disease, based on evidence and defined through a participatory process of expert consensus, for the Latin American context.Articlehttps://pubmed.ncbi.nlm.nih.gov/39999620https://doi.org/10.1016/j.bjid.2025.10451710.1016/j.bjid.2025.104517https://hdl.handle.net/20.500.15037/759W4407882346enThe Brazilian Journal of Infectious Diseases1413-86701678-43912025-02-242026-06-13T09:34:19Z2026-06-13T09:34:19Z |
| spellingShingle | Aspergillosis Context (archaeology) Guideline Intensive care medicine Medicine Disease Immunology Pathology Biology Paleontology Aspergillosis Context (archaeology) Guideline Intensive care medicine Medicine Disease Immunology Pathology Biology Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Humans Humans Humans Humans Humans Immunocompromised Host Immunocompromised Host Immunocompromised Host Immunocompromised Host Immunocompromised Host Evidence-Based Medicine Evidence-Based Medicine Evidence-Based Medicine Evidence-Based Medicine standards Evidence-Based Medicine standards Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms immunology Hematologic Neoplasms immunology Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis immunology Invasive Pulmonary Aspergillosis immunology Invasive Pulmonary Aspergillosis microbiology Invasive Pulmonary Aspergillosis microbiology Health Sciences Medicine Infectious Diseases Antifungal resistance and susceptibility Health Sciences Medicine Epidemiology Fungal Infections and Studies Health Sciences Veterinary Small Animals Infectious Diseases and Mycology Jorge Alberto Cortés Diego Andrés Rodríguez Lugo Martha Carolina Valderrama-Ríos Ricardo Rabagliati Domênico Capone Carlos Álvarez Fabio Varón-Vega Laura Cristina Nócua-Báez Cándida Díaz‐Brochero Leonardo Enciso-Olivera Sonia Isabel Cuervo Luis Thompson Dora Corzo-León Luis E. Cuéllar Erika Paola Vergara Fernando Riera Patricia Cornejo‐Juárez Rita Rojas Beatriz L. Gómez Adriana Marcela Celis Ramírez José Luis Sandoval‐Gutiérrez Mauricio Sarmiento Diana Lorena Ochoa Márcio Nucci Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| title | Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| title_full | Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| title_fullStr | Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| title_full_unstemmed | Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| title_short | Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| title_sort | evidence based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease |
| topic | Aspergillosis Context (archaeology) Guideline Intensive care medicine Medicine Disease Immunology Pathology Biology Paleontology Aspergillosis Context (archaeology) Guideline Intensive care medicine Medicine Disease Immunology Pathology Biology Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Humans Humans Humans Humans Humans Immunocompromised Host Immunocompromised Host Immunocompromised Host Immunocompromised Host Immunocompromised Host Evidence-Based Medicine Evidence-Based Medicine Evidence-Based Medicine Evidence-Based Medicine standards Evidence-Based Medicine standards Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms immunology Hematologic Neoplasms immunology Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis immunology Invasive Pulmonary Aspergillosis immunology Invasive Pulmonary Aspergillosis microbiology Invasive Pulmonary Aspergillosis microbiology Health Sciences Medicine Infectious Diseases Antifungal resistance and susceptibility Health Sciences Medicine Epidemiology Fungal Infections and Studies Health Sciences Veterinary Small Animals Infectious Diseases and Mycology |
| topic_facet | Aspergillosis Context (archaeology) Guideline Intensive care medicine Medicine Disease Immunology Pathology Biology Paleontology Aspergillosis Context (archaeology) Guideline Intensive care medicine Medicine Disease Immunology Pathology Biology Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Antifungal Agents therapeutic use Humans Humans Humans Humans Humans Immunocompromised Host Immunocompromised Host Immunocompromised Host Immunocompromised Host Immunocompromised Host Evidence-Based Medicine Evidence-Based Medicine Evidence-Based Medicine Evidence-Based Medicine standards Evidence-Based Medicine standards Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms complications Hematologic Neoplasms immunology Hematologic Neoplasms immunology Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis diagnosis Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis drug therapy Invasive Pulmonary Aspergillosis immunology Invasive Pulmonary Aspergillosis immunology Invasive Pulmonary Aspergillosis microbiology Invasive Pulmonary Aspergillosis microbiology Health Sciences Medicine Infectious Diseases Antifungal resistance and susceptibility Health Sciences Medicine Epidemiology Fungal Infections and Studies Health Sciences Veterinary Small Animals Infectious Diseases and Mycology |
| url | https://pubmed.ncbi.nlm.nih.gov/39999620 https://doi.org/10.1016/j.bjid.2025.104517 https://hdl.handle.net/20.500.15037/759 |
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