Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru
BACKGROUND: We assessed sexual behavior and incidence of sexually transmitted infections (STIs) among men who have sex with men and transgender women participating in Sabes, a study of an expanded treatment as prevention strategy focused on early diagnosis and treatment of HIV infection in Lima, Per...
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2020
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| author | Michalina A. Montaño Ricardo Alfaro Tara Ness Carmela Ganoza Pedro Gonzáles Jorge Sánchez Javier R. Lama Ann Duerr |
| author_browse | Ann Duerr Carmela Ganoza Javier R. Lama Jorge Sánchez Michalina A. Montaño Pedro Gonzáles Ricardo Alfaro Tara Ness |
| author_facet | Michalina A. Montaño Ricardo Alfaro Tara Ness Carmela Ganoza Pedro Gonzáles Jorge Sánchez Javier R. Lama Ann Duerr |
| author_sort | Michalina A. Montaño |
| collection | Producción científica |
| description | BACKGROUND: We assessed sexual behavior and incidence of sexually transmitted infections (STIs) among men who have sex with men and transgender women participating in Sabes, a study of an expanded treatment as prevention strategy focused on early diagnosis and treatment of HIV infection in Lima, Peru (2013-2017). METHODS: Sabes participants were tested monthly for HIV to identify acute or early infections, and HIV-positive participants were randomized to receive antiretroviral therapy immediately (immediate arm) or after 24 weeks (deferred arm) during a 48-week follow-up period. Sexual behavior was assessed at randomization (baseline) and every 12 weeks thereafter. Participants were tested for urethral and rectal chlamydia and gonorrhea and for syphilis at baseline, 12, 24, and 48 weeks. We describe patterns of sexual behavior during the 48-week follow-up period and compare sexual behavior and STI incidence between study arms. RESULTS: After randomization, 207 HIV-positive participants completed questionnaires and STI testing at 2 or more visits. After HIV diagnosis, participants in both arms reported increases in condom use with main and casual partners and decreased drug and alcohol use before or during anal sex. We observed no between-arm differences in sexual behavior. Deferred arm participants had higher incidence of chlamydia (incidence rate ratio, 2.33; 95% confidence interval, 1.14-4.77) but not gonorrhea or syphilis. CONCLUSIONS: Despite reported increases in condom use, the overall high incidence of STIs reflects some ongoing condomless sex among HIV-positive men who have sex with men and transgender women, highlighting the importance of regular STI screening and counseling to support consistent condom use among HIV-positive individuals at risk for STIs. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/1765 |
| institution | UPeU |
| language | English |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
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| spelling | oai:cris.upeu.edu.pe:20.500.15037/17652026-10-30T16:16:43ZSexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, PeruMichalina A. MontañoRicardo AlfaroTara NessCarmela GanozaPedro GonzálesJorge SánchezJavier R. LamaAnn DuerrMedicineGonorrheaChlamydiaSyphilisMen who have sex with menCondomIncidence (geometry)Transgender womenDemographySexually transmitted diseaseGynecologyHuman immunodeficiency virus (HIV)Family medicineImmunologyOpticsSociologyPhysicsMedicineGonorrheaChlamydiaSyphilisMen who have sex with menCondomIncidence (geometry)Transgender womenDemographySexually transmitted diseaseGynecologyHuman immunodeficiency virus (HIV)Family medicineImmunologySexual and Gender MinoritiesSexual and Gender MinoritiesSexual and Gender MinoritiesSexual and Gender MinoritiesAdultAdultAdultAdultFemaleFemaleFemaleFemaleHumansHumansHumansHumansMaleMaleMaleMalePeru epidemiologyPeru epidemiologyPeru epidemiologyPeru epidemiologySexual Behavior statistics & numerical dataSexual Behavior statistics & numerical dataSexual Behavior statistics & numerical dataSexual Behavior statistics & numerical dataSexual PartnersSexual PartnersSexual PartnersSexual PartnersSexually Transmitted Diseases epidemiologySexually Transmitted Diseases epidemiologySexually Transmitted Diseases epidemiologySexually Transmitted Diseases epidemiologyHIV Infections drug therapyHIV Infections drug therapyHIV Infections drug therapyHIV Infections drug therapyHIV Infections epidemiologyHIV Infections epidemiologyHIV Infections epidemiologyHIV Infections epidemiologyHomosexuality, Male psychologyHomosexuality, Male psychologyHomosexuality, Male psychologyHomosexuality, Male psychologyHomosexuality, Male statistics & numerical dataHomosexuality, Male statistics & numerical dataHomosexuality, Male statistics & numerical dataHomosexuality, Male statistics & numerical dataAntiretroviral Therapy, Highly Active methodsAntiretroviral Therapy, Highly Active methodsAntiretroviral Therapy, Highly Active methodsAntiretroviral Therapy, Highly Active methodsTransgender Persons psychologyTransgender Persons psychologyTransgender Persons psychologyTransgender Persons psychologyTransgender Persons statistics & numerical dataTransgender Persons statistics & numerical dataTransgender Persons statistics & numerical dataTransgender Persons statistics & numerical dataHealth Sciences Medicine Infectious Diseases HIV/AIDS Research and InterventionsHealth Sciences Health Professions General Health Professions Adolescent Sexual and Reproductive HealthLife Sciences Immunology and Microbiology Microbiology Reproductive tract infections researchBACKGROUND: We assessed sexual behavior and incidence of sexually transmitted infections (STIs) among men who have sex with men and transgender women participating in Sabes, a study of an expanded treatment as prevention strategy focused on early diagnosis and treatment of HIV infection in Lima, Peru (2013-2017). METHODS: Sabes participants were tested monthly for HIV to identify acute or early infections, and HIV-positive participants were randomized to receive antiretroviral therapy immediately (immediate arm) or after 24 weeks (deferred arm) during a 48-week follow-up period. Sexual behavior was assessed at randomization (baseline) and every 12 weeks thereafter. Participants were tested for urethral and rectal chlamydia and gonorrhea and for syphilis at baseline, 12, 24, and 48 weeks. We describe patterns of sexual behavior during the 48-week follow-up period and compare sexual behavior and STI incidence between study arms. RESULTS: After randomization, 207 HIV-positive participants completed questionnaires and STI testing at 2 or more visits. After HIV diagnosis, participants in both arms reported increases in condom use with main and casual partners and decreased drug and alcohol use before or during anal sex. We observed no between-arm differences in sexual behavior. Deferred arm participants had higher incidence of chlamydia (incidence rate ratio, 2.33; 95% confidence interval, 1.14-4.77) but not gonorrhea or syphilis. CONCLUSIONS: Despite reported increases in condom use, the overall high incidence of STIs reflects some ongoing condomless sex among HIV-positive men who have sex with men and transgender women, highlighting the importance of regular STI screening and counseling to support consistent condom use among HIV-positive individuals at risk for STIs.Articlehttps://pubmed.ncbi.nlm.nih.gov/33186338https://www.ncbi.nlm.nih.gov/pmc/articles/767271510.1097/olq.0000000000001310https://hdl.handle.net/20.500.15037/1765W3102626245enSexually Transmitted Diseases0148-57171537-45212020-11-112026-06-13T14:21:50Z2026-06-13T14:21:50Z |
| spellingShingle | Medicine Gonorrhea Chlamydia Syphilis Men who have sex with men Condom Incidence (geometry) Transgender women Demography Sexually transmitted disease Gynecology Human immunodeficiency virus (HIV) Family medicine Immunology Optics Sociology Physics Medicine Gonorrhea Chlamydia Syphilis Men who have sex with men Condom Incidence (geometry) Transgender women Demography Sexually transmitted disease Gynecology Human immunodeficiency virus (HIV) Family medicine Immunology Sexual and Gender Minorities Sexual and Gender Minorities Sexual and Gender Minorities Sexual and Gender Minorities Adult Adult Adult Adult Female Female Female Female Humans Humans Humans Humans Male Male Male Male Peru epidemiology Peru epidemiology Peru epidemiology Peru epidemiology Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Partners Sexual Partners Sexual Partners Sexual Partners Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology HIV Infections drug therapy HIV Infections drug therapy HIV Infections drug therapy HIV Infections drug therapy HIV Infections epidemiology HIV Infections epidemiology HIV Infections epidemiology HIV Infections epidemiology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Transgender Persons psychology Transgender Persons psychology Transgender Persons psychology Transgender Persons psychology Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Health Sciences Medicine Infectious Diseases HIV/AIDS Research and Interventions Health Sciences Health Professions General Health Professions Adolescent Sexual and Reproductive Health Life Sciences Immunology and Microbiology Microbiology Reproductive tract infections research Michalina A. Montaño Ricardo Alfaro Tara Ness Carmela Ganoza Pedro Gonzáles Jorge Sánchez Javier R. Lama Ann Duerr Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru |
| title | Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru |
| title_full | Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru |
| title_fullStr | Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru |
| title_full_unstemmed | Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru |
| title_short | Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru |
| title_sort | sexual behavior and sexually transmitted infection outcomes among men who have sex with men and transgender women participating in a study of the timing of antiretroviral therapy in lima peru |
| topic | Medicine Gonorrhea Chlamydia Syphilis Men who have sex with men Condom Incidence (geometry) Transgender women Demography Sexually transmitted disease Gynecology Human immunodeficiency virus (HIV) Family medicine Immunology Optics Sociology Physics Medicine Gonorrhea Chlamydia Syphilis Men who have sex with men Condom Incidence (geometry) Transgender women Demography Sexually transmitted disease Gynecology Human immunodeficiency virus (HIV) Family medicine Immunology Sexual and Gender Minorities Sexual and Gender Minorities Sexual and Gender Minorities Sexual and Gender Minorities Adult Adult Adult Adult Female Female Female Female Humans Humans Humans Humans Male Male Male Male Peru epidemiology Peru epidemiology Peru epidemiology Peru epidemiology Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Partners Sexual Partners Sexual Partners Sexual Partners Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology HIV Infections drug therapy HIV Infections drug therapy HIV Infections drug therapy HIV Infections drug therapy HIV Infections epidemiology HIV Infections epidemiology HIV Infections epidemiology HIV Infections epidemiology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Transgender Persons psychology Transgender Persons psychology Transgender Persons psychology Transgender Persons psychology Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Health Sciences Medicine Infectious Diseases HIV/AIDS Research and Interventions Health Sciences Health Professions General Health Professions Adolescent Sexual and Reproductive Health Life Sciences Immunology and Microbiology Microbiology Reproductive tract infections research |
| topic_facet | Medicine Gonorrhea Chlamydia Syphilis Men who have sex with men Condom Incidence (geometry) Transgender women Demography Sexually transmitted disease Gynecology Human immunodeficiency virus (HIV) Family medicine Immunology Optics Sociology Physics Medicine Gonorrhea Chlamydia Syphilis Men who have sex with men Condom Incidence (geometry) Transgender women Demography Sexually transmitted disease Gynecology Human immunodeficiency virus (HIV) Family medicine Immunology Sexual and Gender Minorities Sexual and Gender Minorities Sexual and Gender Minorities Sexual and Gender Minorities Adult Adult Adult Adult Female Female Female Female Humans Humans Humans Humans Male Male Male Male Peru epidemiology Peru epidemiology Peru epidemiology Peru epidemiology Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Behavior statistics & numerical data Sexual Partners Sexual Partners Sexual Partners Sexual Partners Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology Sexually Transmitted Diseases epidemiology HIV Infections drug therapy HIV Infections drug therapy HIV Infections drug therapy HIV Infections drug therapy HIV Infections epidemiology HIV Infections epidemiology HIV Infections epidemiology HIV Infections epidemiology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male psychology Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Homosexuality, Male statistics & numerical data Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Antiretroviral Therapy, Highly Active methods Transgender Persons psychology Transgender Persons psychology Transgender Persons psychology Transgender Persons psychology Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Transgender Persons statistics & numerical data Health Sciences Medicine Infectious Diseases HIV/AIDS Research and Interventions Health Sciences Health Professions General Health Professions Adolescent Sexual and Reproductive Health Life Sciences Immunology and Microbiology Microbiology Reproductive tract infections research |
| url | https://pubmed.ncbi.nlm.nih.gov/33186338 https://www.ncbi.nlm.nih.gov/pmc/articles/7672715 https://hdl.handle.net/20.500.15037/1765 |
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