Gene score to quantify systemic inflammation in patients with acutely decompensated cirrhosis

BACKGROUND AND AIMS: Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance because SI is a driver of the most severe forms of ADC, including acute-on-chronic liver failure (ACLF). Blood biomarkers of SI already evaluated in ADC failed to appropriately...

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Autores principales: Jonel Trebicka, Ferrán Aguilar, Alberto Queiróz Farias, Juan José Lozano, Cristina Sánchez-Garrido, Eva Usón-Raposo, Carlos de la Peña-Ramirez, Julia Sidorova, Anna Curto, Patricia Sierra-Casas, Patrícia Momoyo Zitelli, Mária Papp, Gustavo Pereira, Paolo Caraceni, Luciana L Goncalves, Carlo Alessandria, Aldo Torre, Wim Laleman, Adrián Gadano, Salvatore Piano, Ângelo Zambam de Mattos, Wen Gu, Maximilian Joseph Brol, Robert Schierwagen, Frank Erhard Uschner, Julia Fischer, Liliana Sampaio Costa Mendes, Víctor Manuel Vargas, Mário Reis Álvares‐da‐Silva, Rajeshwar P. Mookerjee, Paulo Lisboa Bittencourt, Carlos Benítez, Agustı́n Albillos, Cláudia Alves Couto, Manuel Mendizábal, Rafael Bañares, Claudio Toledo, Daniel Ferraz de Campos Mazo, Martin Janíčko, M. Castillo-Barradas, Martín Padilla, Pietro Gatti, Alina Miranda, R. Malé-Velázquez, Alexander Zipprich, André Castro-Lyra, Thierry Gustot, William Bernal, Alexander L. Gerbes, Rajiv Jalan, Javier Fernández, Paolo Angeli, Flair José Carrilho, Joan Clària, Richard Moreau, Vicente Arroyo
Formato: Artículo
Lenguaje:inglés
Publicado: 2025
Materias:
Medicine
Systemic inflammation
Cirrhosis
White blood cell
Internal medicine
Inflammation
Framingham Risk Score
Immune system
Gastroenterology
Oncology
Immunology
Disease
Aged
C-Reactive Protein analysis
Female
Humans
Inflammation blood
Inflammation genetics
Leukocyte Count
Liver Cirrhosis blood
Liver Cirrhosis complications
Liver Cirrhosis genetics
Male
Middle Aged
Severity of Illness Index
Biomarkers blood
Cytokines blood
Acute-On-Chronic Liver Failure blood
Acute-On-Chronic Liver Failure etiology
Acute-On-Chronic Liver Failure genetics
Health Sciences Medicine Hepatology Liver Disease and Transplantation
Life Sciences Immunology and Microbiology Immunology Immune Response and Inflammation
Health Sciences Medicine Epidemiology Sepsis Diagnosis and Treatment
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