Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results

BACKGROUND: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs - remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a - in patients hospitalized with coronavirus disease 2019 (Covid-19). METHODS: We randomly assigned inpatients with C...

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Autor principal: Alvarez Manrique, Victor Daniel
Formato: Artículo
Lenguaje:inglés
Publicado: 2020
Materias:
Coronavirus disease 2019 (COVID-19)
Interim
Solidarity
2019-20 coronavirus outbreak
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Virology
Medicine
Political science
Internal medicine
Law
Outbreak
Disease
Politics
Infectious disease (medical specialty)
Interferon beta-1a therapeutic use
COVID-19 mortality
COVID-19 Drug Treatment
Adenosine Monophosphate analogs & derivatives
Adenosine Monophosphate therapeutic use
Aged
Alanine analogs & derivatives
Alanine therapeutic use
Antiviral Agents administration & dosage
Antiviral Agents adverse effects
Antiviral Agents therapeutic use
Drug Therapy, Combination
Female
Hospitalization
Humans
Hydroxychloroquine therapeutic use
Length of Stay
Male
Middle Aged
Respiration, Artificial
Hospital Mortality
Treatment Failure
Kaplan-Meier Estimate
Intention to Treat Analysis
Lopinavir therapeutic use
Health Sciences Medicine Infectious Diseases COVID-19 Clinical Research Studies
Health Sciences Medicine Infectious Diseases SARS-CoV-2 and COVID-19 Research
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology Pharmacological Receptor Mechanisms and Effects
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