Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023

ABSTRACT Background Multidomain health indicators, including chronic disease indicators, risk behaviors, health habits, depressive symptomatology, disability indicators, and healthcare‐access indicators, may be interconnected through complex patterns of conditional association. Network analysis prov...

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Autores principales: Miguel Basauri-Delgado, Deysi Pedraza Ricra, Maryuri Natalia More Espinoza, Ruth Gabriela Yapo‐Esteban, Jacksaint Saintila
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Publicado: 2026
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author Miguel Basauri-Delgado
Deysi Pedraza Ricra
Maryuri Natalia More Espinoza
Ruth Gabriela Yapo‐Esteban
Jacksaint Saintila
author_browse Deysi Pedraza Ricra
Jacksaint Saintila
Maryuri Natalia More Espinoza
Miguel Basauri-Delgado
Ruth Gabriela Yapo‐Esteban
author_facet Miguel Basauri-Delgado
Deysi Pedraza Ricra
Maryuri Natalia More Espinoza
Ruth Gabriela Yapo‐Esteban
Jacksaint Saintila
author_sort Miguel Basauri-Delgado
collection Producción científica
description ABSTRACT Background Multidomain health indicators, including chronic disease indicators, risk behaviors, health habits, depressive symptomatology, disability indicators, and healthcare‐access indicators, may be interconnected through complex patterns of conditional association. Network analysis provides an exploratory framework for estimating such interdependencies without implying causality or clinically confirmed comorbidity patterns. Objective To estimate the network structure of conditional associations among selected ENDES health‐related indicators in an analytic sample of Peruvian adults from 2021 to 2023, and to descriptively explore sex‐specific patterns. Methods A secondary analysis was conducted using ENDES 2021–2023 data. A total of 92,101 respondents aged 18 years or older who completed the Health Questionnaire module and had complete data for the selected variables were included. Twenty‐one indicators selected a priori from five domains—chronic disease indicators, behavioral risks, health habits, disability/depressive symptomatology, and healthcare‐access/anthropometric context—were modeled using a mixed graphical model. Bootstrapped edge‐weight accuracy and Expected Influence stability diagnostics were added. Sex‐specific networks were examined descriptively, without a formal Network Comparison Test. Results The overall network showed positive conditional associations among smoking indicators and alcohol consumption, among disability indicators, and between age and hypertension, diabetes, visual disability, and motor disability. Negative conditional associations were observed between daily smoking and both health insurance coverage and fruit consumption, as well as between depressive symptomatology and fruit‐based indicators. In sex‐specific networks, men showed a descriptively denser disability‐related clustering than women, but these visual differences were not inferentially tested. Conclusions Selected multidomain ENDES health‐related indicators were conditionally interconnected in the analytic sample. Findings should be interpreted as exploratory and hypothesis‐generating and do not imply causality, directionality, nationally weighted network estimates, statistically confirmed sex differences, or clinically confirmed comorbidity patterns.
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spelling openalex:W7204159937Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023Miguel Basauri-DelgadoDeysi Pedraza RicraMaryuri Natalia More EspinozaRuth Gabriela Yapo‐EstebanJacksaint Saintilarisk-takinghealth habitsdisabilitydepressive symptomshealth care accesssmokingalcohol consumptionhypertensiondiabetes mellitusvisual impairmentmotor impairmentfruit consumptionhealth insurance coveragesex differencesconditional associationnetwork structurePeruvian adultsMental Health Research TopicsChronic Disease Management StrategiesHealth disparities and outcomesABSTRACT Background Multidomain health indicators, including chronic disease indicators, risk behaviors, health habits, depressive symptomatology, disability indicators, and healthcare‐access indicators, may be interconnected through complex patterns of conditional association. Network analysis provides an exploratory framework for estimating such interdependencies without implying causality or clinically confirmed comorbidity patterns. Objective To estimate the network structure of conditional associations among selected ENDES health‐related indicators in an analytic sample of Peruvian adults from 2021 to 2023, and to descriptively explore sex‐specific patterns. Methods A secondary analysis was conducted using ENDES 2021–2023 data. A total of 92,101 respondents aged 18 years or older who completed the Health Questionnaire module and had complete data for the selected variables were included. Twenty‐one indicators selected a priori from five domains—chronic disease indicators, behavioral risks, health habits, disability/depressive symptomatology, and healthcare‐access/anthropometric context—were modeled using a mixed graphical model. Bootstrapped edge‐weight accuracy and Expected Influence stability diagnostics were added. Sex‐specific networks were examined descriptively, without a formal Network Comparison Test. Results The overall network showed positive conditional associations among smoking indicators and alcohol consumption, among disability indicators, and between age and hypertension, diabetes, visual disability, and motor disability. Negative conditional associations were observed between daily smoking and both health insurance coverage and fruit consumption, as well as between depressive symptomatology and fruit‐based indicators. In sex‐specific networks, men showed a descriptively denser disability‐related clustering than women, but these visual differences were not inferentially tested. Conclusions Selected multidomain ENDES health‐related indicators were conditionally interconnected in the analytic sample. Findings should be interpreted as exploratory and hypothesis‐generating and do not imply causality, directionality, nationally weighted network estimates, statistically confirmed sex differences, or clinically confirmed comorbidity patterns.Articlehttps://doi.org/10.1002/lim2.70071https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/lim2.70071W7204159937enLifestyle Medicine2688-37402026-08-25
spellingShingle risk-taking
health habits
disability
depressive symptoms
health care access
smoking
alcohol consumption
hypertension
diabetes mellitus
visual impairment
motor impairment
fruit consumption
health insurance coverage
sex differences
conditional association
network structure
Peruvian adults
Mental Health Research Topics
Chronic Disease Management Strategies
Health disparities and outcomes
Miguel Basauri-Delgado
Deysi Pedraza Ricra
Maryuri Natalia More Espinoza
Ruth Gabriela Yapo‐Esteban
Jacksaint Saintila
Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023
title Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023
title_full Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023
title_fullStr Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023
title_full_unstemmed Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023
title_short Conditional Associations Among Chronic Disease Indicators, Risk Behaviors, Health Habits, and Disability Indicators in an Analytic ENDES Sample of Peruvian Adults: A Secondary Analysis Using Exploratory Network Analysis, 2021–2023
title_sort conditional associations among chronic disease indicators risk behaviors health habits and disability indicators in an analytic endes sample of peruvian adults a secondary analysis using exploratory network analysis 2021 2023
topic risk-taking
health habits
disability
depressive symptoms
health care access
smoking
alcohol consumption
hypertension
diabetes mellitus
visual impairment
motor impairment
fruit consumption
health insurance coverage
sex differences
conditional association
network structure
Peruvian adults
Mental Health Research Topics
Chronic Disease Management Strategies
Health disparities and outcomes
topic_facet risk-taking
health habits
disability
depressive symptoms
health care access
smoking
alcohol consumption
hypertension
diabetes mellitus
visual impairment
motor impairment
fruit consumption
health insurance coverage
sex differences
conditional association
network structure
Peruvian adults
Mental Health Research Topics
Chronic Disease Management Strategies
Health disparities and outcomes
url https://doi.org/10.1002/lim2.70071
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/lim2.70071
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