Clinical case giant malignant phyllodes tumor of the breast
Malignant phyllodes tumor is a rare and aggressive breast neoplasm with the potential for rapid and recurrent growth. We present the case of a 56-year-old woman from San Martín, Peru, with a left breast mass exhibiting exponential growth, ulceration, necrosis, and asymmetry. Physical examination rev...
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| Formato: | Artículo |
| Lenguaje: | inglés |
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2026
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| author | Alan Hari Silva Amaya Julio Caleb Arrieta Navarro Alvaro Micael Ñaña-Cordova Elkin J Pelaes Cruz Sorely Pacovilca Chura |
| author_browse | Alan Hari Silva Amaya Alvaro Micael Ñaña-Cordova Elkin J Pelaes Cruz Julio Caleb Arrieta Navarro Sorely Pacovilca Chura |
| author_facet | Alan Hari Silva Amaya Julio Caleb Arrieta Navarro Alvaro Micael Ñaña-Cordova Elkin J Pelaes Cruz Sorely Pacovilca Chura |
| author_sort | Alan Hari Silva Amaya |
| collection | Producción científica |
| description | Malignant phyllodes tumor is a rare and aggressive breast neoplasm with the potential for rapid and recurrent growth. We present the case of a 56-year-old woman from San Martín, Peru, with a left breast mass exhibiting exponential growth, ulceration, necrosis, and asymmetry. Physical examination revealed a multinodular, purplish-red, indurated, and slightly painful mass. Ultrasound showed a 12-cm hypoechoic, heterogeneous mass with areas of necrosis, increased vascularity, and contact with the muscle layer (Breast Imaging Reporting and Data System category 4). Core biopsy revealed a fibroepithelial neoplasm with high mitotic activity (10/10 HPF). The patient underwent left total mastectomy with subsequent margin extension and partial-thickness skin grafting, achieving complete resection and satisfactory recovery. This case highlights the challenges in the diagnosis and surgical management of this pathology in resource-limited settings where timely surgery plays a crucial role in treatment and prevents recurrence. |
| format | Article |
| id | openalex:W7204059389 |
| institution | UPeU |
| language | English |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| record_format | dspace |
| spelling | openalex:W7204059389Clinical case giant malignant phyllodes tumor of the breastAlan Hari Silva AmayaJulio Caleb Arrieta NavarroAlvaro Micael Ñaña-CordovaElkin J Pelaes CruzSorely Pacovilca Churamalignant phyllodes tumorgiant breast tumorbreast cancertotal mastectomyBI-RADS 4rapid tumor growthresource-limited settingssurgical managementBreast Lesions and CarcinomasCancer and Skin LesionsUterine Myomas and TreatmentsMalignant phyllodes tumor is a rare and aggressive breast neoplasm with the potential for rapid and recurrent growth. We present the case of a 56-year-old woman from San Martín, Peru, with a left breast mass exhibiting exponential growth, ulceration, necrosis, and asymmetry. Physical examination revealed a multinodular, purplish-red, indurated, and slightly painful mass. Ultrasound showed a 12-cm hypoechoic, heterogeneous mass with areas of necrosis, increased vascularity, and contact with the muscle layer (Breast Imaging Reporting and Data System category 4). Core biopsy revealed a fibroepithelial neoplasm with high mitotic activity (10/10 HPF). The patient underwent left total mastectomy with subsequent margin extension and partial-thickness skin grafting, achieving complete resection and satisfactory recovery. This case highlights the challenges in the diagnosis and surgical management of this pathology in resource-limited settings where timely surgery plays a crucial role in treatment and prevents recurrence.Articlehttps://doi.org/10.1093/jscr/rjag735W7204059389enJournal of Surgical Case Reports2042-88122026-08-01 |
| spellingShingle | malignant phyllodes tumor giant breast tumor breast cancer total mastectomy BI-RADS 4 rapid tumor growth resource-limited settings surgical management Breast Lesions and Carcinomas Cancer and Skin Lesions Uterine Myomas and Treatments Alan Hari Silva Amaya Julio Caleb Arrieta Navarro Alvaro Micael Ñaña-Cordova Elkin J Pelaes Cruz Sorely Pacovilca Chura Clinical case giant malignant phyllodes tumor of the breast |
| title | Clinical case giant malignant phyllodes tumor of the breast |
| title_full | Clinical case giant malignant phyllodes tumor of the breast |
| title_fullStr | Clinical case giant malignant phyllodes tumor of the breast |
| title_full_unstemmed | Clinical case giant malignant phyllodes tumor of the breast |
| title_short | Clinical case giant malignant phyllodes tumor of the breast |
| title_sort | clinical case giant malignant phyllodes tumor of the breast |
| topic | malignant phyllodes tumor giant breast tumor breast cancer total mastectomy BI-RADS 4 rapid tumor growth resource-limited settings surgical management Breast Lesions and Carcinomas Cancer and Skin Lesions Uterine Myomas and Treatments |
| topic_facet | malignant phyllodes tumor giant breast tumor breast cancer total mastectomy BI-RADS 4 rapid tumor growth resource-limited settings surgical management Breast Lesions and Carcinomas Cancer and Skin Lesions Uterine Myomas and Treatments |
| url | https://doi.org/10.1093/jscr/rjag735 |
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