Cerebral hemodynamic changes at high altitude in adults: a systematic review and meta-analysis of transcranial Doppler and duplex ultrasound studies

In this first global meta-analysis of ultrasound-based cerebral hemodynamics at ≥1,500 m, we show that altitude exposure is associated with lower cerebral blood flow velocity, volumetric flow, arterial diameter, and oxygen saturation in healthy adults. Native status, age, and altitude level partly e...

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Autores principales:	Jean Pierre Zila-Velasque, Pamela Grados‐Espinoza, Sebastian Abanto-Urbano, Mely Olarte-Durand, Martha Isabel Vilca-Salas, Paula Moran-Ballon, Carlos Quispe‐Vicuña, Victor Velásquez‐Rimachi, Joel M. Sequeiros, Kateriny Margot Regalado-Rodríguez, Patrick E. Zila-Velasque, Sthefano E. Zila-Velasque, Sheidy Clemente-Tueros, Fernando Terry, Carlos Alva‐Díaz
Formato:	Artículo de revisión
Lenguaje:	inglés
Publicado:	2026
Materias:	high altitude cerebral hemodynamics cerebral blood flow velocity cerebral blood flow cerebral oxygen saturation cerebral arteries arterial diameter high-altitude adaptation cerebral perfusion High Altitude and Hypoxia Spaceflight effects on biology Thermoregulation and physiological responses
Acceso en línea:	Enlace permanente (DOI o Handle)
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