Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study
INTRODUCTION: Poor sleep quality is common among medical students and is associated with academic and health-related consequences. Gastroesophageal reflux disease (GERD) may contribute to sleep disturbances through biological and behavioral mechanisms, however, evidence in medical students is limite...
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2026
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| author | Alvaro F. Montalvo-Peralta Yolanda Abigail Miranda-Sagastegui Frank J. Tinco-Pumacahua David R. Soriano‐Moreno |
| author_browse | Alvaro F. Montalvo-Peralta David R. Soriano‐Moreno Frank J. Tinco-Pumacahua Yolanda Abigail Miranda-Sagastegui |
| author_facet | Alvaro F. Montalvo-Peralta Yolanda Abigail Miranda-Sagastegui Frank J. Tinco-Pumacahua David R. Soriano‐Moreno |
| author_sort | Alvaro F. Montalvo-Peralta |
| collection | Producción científica |
| description | INTRODUCTION: Poor sleep quality is common among medical students and is associated with academic and health-related consequences. Gastroesophageal reflux disease (GERD) may contribute to sleep disturbances through biological and behavioral mechanisms, however, evidence in medical students is limited and previous studies have not adequately controlled for confounding. OBJECTIVE: To evaluate the association between GERD and sleep quality among medical students in Lima, Peru. METHODS: Cross-sectional analytical study conducted among medical students from a private university in Lima, Peru. Sleep quality was assessed using the Pittsburgh Sleep Quality Index, and GERD symptoms were measured with the Frequency Scale for the Symptoms of GERD. Poisson regression with robust variance was used to estimate adjusted prevalence ratios (aPR) with 95% confidence intervals (95% CI). RESULTS: A total of 171 students were analyzed (median age: 22 years; 64.9% female). The prevalence of GERD symptom burden was 76.6%, and poor sleep quality was observed in 84.8% of participants. Students with GERD symptom burden had a higher prevalence of poor sleep quality compared to those without GERD (aPR: 1.27; 95% CI: 1.03 to 1.58). Additionally, for each one-point increase in the GERD symptom score, the prevalence of poor sleep quality increased by 1.0% (aPR: 1.01; 95% CI: 1.003 to 1.018), demonstrating a dose-response relationship. CONCLUSION: GERD symptoms were significantly associated with poor sleep quality among Peruvian medical students. This study provides context-specific adjusted evidence from an understudied Latin American medical student population. These findings support the need for screening strategies and early interventions targeting both conditions in this population. |
| format | Article |
| id | openalex:W7163048977 |
| institution | UPeU |
| language | English |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| record_format | dspace |
| spelling | openalex:W7163048977Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional studyAlvaro F. Montalvo-PeraltaYolanda Abigail Miranda-SagasteguiFrank J. Tinco-PumacahuaDavid R. Soriano‐Morenogastroesophageal reflux diseaseGERD symptomssleep qualitymedical studentssleep disordersuniversity studentsprevalencedose-response relationshipGastroesophageal reflux and treatmentsSleep and related disordersGastrointestinal motility and disordersINTRODUCTION: Poor sleep quality is common among medical students and is associated with academic and health-related consequences. Gastroesophageal reflux disease (GERD) may contribute to sleep disturbances through biological and behavioral mechanisms, however, evidence in medical students is limited and previous studies have not adequately controlled for confounding. OBJECTIVE: To evaluate the association between GERD and sleep quality among medical students in Lima, Peru. METHODS: Cross-sectional analytical study conducted among medical students from a private university in Lima, Peru. Sleep quality was assessed using the Pittsburgh Sleep Quality Index, and GERD symptoms were measured with the Frequency Scale for the Symptoms of GERD. Poisson regression with robust variance was used to estimate adjusted prevalence ratios (aPR) with 95% confidence intervals (95% CI). RESULTS: A total of 171 students were analyzed (median age: 22 years; 64.9% female). The prevalence of GERD symptom burden was 76.6%, and poor sleep quality was observed in 84.8% of participants. Students with GERD symptom burden had a higher prevalence of poor sleep quality compared to those without GERD (aPR: 1.27; 95% CI: 1.03 to 1.58). Additionally, for each one-point increase in the GERD symptom score, the prevalence of poor sleep quality increased by 1.0% (aPR: 1.01; 95% CI: 1.003 to 1.018), demonstrating a dose-response relationship. CONCLUSION: GERD symptoms were significantly associated with poor sleep quality among Peruvian medical students. This study provides context-specific adjusted evidence from an understudied Latin American medical student population. These findings support the need for screening strategies and early interventions targeting both conditions in this population.Articlehttps://doi.org/10.1371/journal.pone.0348891https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0348891&type=printableW7163048977enPLoS ONE1932-62032026-06-01 |
| spellingShingle | gastroesophageal reflux disease GERD symptoms sleep quality medical students sleep disorders university students prevalence dose-response relationship Gastroesophageal reflux and treatments Sleep and related disorders Gastrointestinal motility and disorders Alvaro F. Montalvo-Peralta Yolanda Abigail Miranda-Sagastegui Frank J. Tinco-Pumacahua David R. Soriano‐Moreno Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study |
| title | Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study |
| title_full | Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study |
| title_fullStr | Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study |
| title_full_unstemmed | Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study |
| title_short | Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study |
| title_sort | gastroesophageal reflux symptoms and sleep quality among medical students at a private university in lima peru a cross sectional study |
| topic | gastroesophageal reflux disease GERD symptoms sleep quality medical students sleep disorders university students prevalence dose-response relationship Gastroesophageal reflux and treatments Sleep and related disorders Gastrointestinal motility and disorders |
| topic_facet | gastroesophageal reflux disease GERD symptoms sleep quality medical students sleep disorders university students prevalence dose-response relationship Gastroesophageal reflux and treatments Sleep and related disorders Gastrointestinal motility and disorders |
| url | https://doi.org/10.1371/journal.pone.0348891 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0348891&type=printable |
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