bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru
Background Common identification techniques do not differentiate among members of the Acinetobacter calcoaceticus–baumannii (ACB) complex, and the presence of non‐ baumannii Acinetobacter is often misinterpreted. The b l a OXA−51 gene is located within the chromosome of Acinetobacter baumannii . Des...
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2025
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| author | Rosario Oporto-Llerena Rosario Huerto-Huánuco Yaneth Quispe-Hualpa Luciano A. Palomino-Kobayashi Maria Gabriela Soza Bieli-Bianchi Jesús Rojas‐Jaimes Patricia Gonzales Luis Pollack Andrea C. Gómez Gina Salvador-Luján Edwin Antonio Cuaresma Cuadros Néstor Luque Martín Casapía Kovy Arteaga‐Livias Yolanda Sáenz María J. Pons Joaquím Ruiz |
| author_browse | Andrea C. Gómez Edwin Antonio Cuaresma Cuadros Gina Salvador-Luján Jesús Rojas‐Jaimes Joaquím Ruiz Kovy Arteaga‐Livias Luciano A. Palomino-Kobayashi Luis Pollack Maria Gabriela Soza Bieli-Bianchi Martín Casapía María J. Pons Néstor Luque Patricia Gonzales Rosario Huerto-Huánuco Rosario Oporto-Llerena Yaneth Quispe-Hualpa Yolanda Sáenz |
| author_facet | Rosario Oporto-Llerena Rosario Huerto-Huánuco Yaneth Quispe-Hualpa Luciano A. Palomino-Kobayashi Maria Gabriela Soza Bieli-Bianchi Jesús Rojas‐Jaimes Patricia Gonzales Luis Pollack Andrea C. Gómez Gina Salvador-Luján Edwin Antonio Cuaresma Cuadros Néstor Luque Martín Casapía Kovy Arteaga‐Livias Yolanda Sáenz María J. Pons Joaquím Ruiz |
| author_sort | Rosario Oporto-Llerena |
| collection | Producción científica |
| description | Background Common identification techniques do not differentiate among members of the Acinetobacter calcoaceticus–baumannii (ACB) complex, and the presence of non‐ baumannii Acinetobacter is often misinterpreted. The b l a OXA−51 gene is located within the chromosome of Acinetobacter baumannii . Despite its plasmid dissemination to other members of the genus, it may be considered in initial species screening. Thus, this study aimed to determine the presence of b l a OXA−51 ‐negative Acinetobacter spp. as a cause of infection in Peru. Methods Two hundred ninety‐eight ACB complex isolates from different regions of Peru were isolated between January 2018 and March 2024. Of these, 272 and 25 were confirmed as hospital‐acquired and community infections, respectively. The presence of b l a OXA−51 was determined by polymerase chain reaction, and the susceptibility levels to 12 antimicrobial agents were determined. Results The results showed that 38 (12.7%) isolates were b l a OXA−51 ‐negative. These isolates were frequent among community infections (13/25, p < 0.0001), often causing urine infections. They showed significantly lower levels of resistance to almost all antimicrobial agents tested, and most of them were recovered from regions outside metropolitan Lima. Conclusion A relevant number of infections by non‐ baumannii Acinetobacter species in Peru is suggested, highlighting the need for systematic identification of these species in the country. |
| format | Article |
| id | openalex:W4416823724 |
| institution | UPeU |
| language | English |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
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| spelling | openalex:W4416823724bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in PeruRosario Oporto-LlerenaRosario Huerto-HuánucoYaneth Quispe-HualpaLuciano A. Palomino-KobayashiMaria Gabriela Soza Bieli-BianchiJesús Rojas‐JaimesPatricia GonzalesLuis PollackAndrea C. GómezGina Salvador-LujánEdwin Antonio Cuaresma CuadrosNéstor LuqueMartín CasapíaKovy Arteaga‐LiviasYolanda SáenzMaría J. PonsJoaquím RuizAcinetobacter calcoaceticus-baumannii complexblaOXA-51Acinetobacter baumanniiantimicrobial resistanceurinary tract infectioncommunity-acquired infectionsnosocomial infectionsspecies identificationPeruAntibiotic Resistance in BacteriaInfections and bacterial resistanceBacterial Identification and Susceptibility TestingBackground Common identification techniques do not differentiate among members of the Acinetobacter calcoaceticus–baumannii (ACB) complex, and the presence of non‐ baumannii Acinetobacter is often misinterpreted. The b l a OXA−51 gene is located within the chromosome of Acinetobacter baumannii . Despite its plasmid dissemination to other members of the genus, it may be considered in initial species screening. Thus, this study aimed to determine the presence of b l a OXA−51 ‐negative Acinetobacter spp. as a cause of infection in Peru. Methods Two hundred ninety‐eight ACB complex isolates from different regions of Peru were isolated between January 2018 and March 2024. Of these, 272 and 25 were confirmed as hospital‐acquired and community infections, respectively. The presence of b l a OXA−51 was determined by polymerase chain reaction, and the susceptibility levels to 12 antimicrobial agents were determined. Results The results showed that 38 (12.7%) isolates were b l a OXA−51 ‐negative. These isolates were frequent among community infections (13/25, p < 0.0001), often causing urine infections. They showed significantly lower levels of resistance to almost all antimicrobial agents tested, and most of them were recovered from regions outside metropolitan Lima. Conclusion A relevant number of infections by non‐ baumannii Acinetobacter species in Peru is suggested, highlighting the need for systematic identification of these species in the country.Articlehttps://doi.org/10.1155/jotm/8851906W4416823724enJournal of Tropical Medicine1687-96861687-96942025-01-01 |
| spellingShingle | Acinetobacter calcoaceticus-baumannii complex blaOXA-51 Acinetobacter baumannii antimicrobial resistance urinary tract infection community-acquired infections nosocomial infections species identification Peru Antibiotic Resistance in Bacteria Infections and bacterial resistance Bacterial Identification and Susceptibility Testing Rosario Oporto-Llerena Rosario Huerto-Huánuco Yaneth Quispe-Hualpa Luciano A. Palomino-Kobayashi Maria Gabriela Soza Bieli-Bianchi Jesús Rojas‐Jaimes Patricia Gonzales Luis Pollack Andrea C. Gómez Gina Salvador-Luján Edwin Antonio Cuaresma Cuadros Néstor Luque Martín Casapía Kovy Arteaga‐Livias Yolanda Sáenz María J. Pons Joaquím Ruiz bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru |
| title | bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru |
| title_full | bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru |
| title_fullStr | bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru |
| title_full_unstemmed | bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru |
| title_short | bla OXA−51 ‐Negative Acinetobacter calcoaceticus–baumannii Complex as a Cause of Human Infection in Peru |
| title_sort | bla oxa 51 negative acinetobacter calcoaceticus baumannii complex as a cause of human infection in peru |
| topic | Acinetobacter calcoaceticus-baumannii complex blaOXA-51 Acinetobacter baumannii antimicrobial resistance urinary tract infection community-acquired infections nosocomial infections species identification Peru Antibiotic Resistance in Bacteria Infections and bacterial resistance Bacterial Identification and Susceptibility Testing |
| topic_facet | Acinetobacter calcoaceticus-baumannii complex blaOXA-51 Acinetobacter baumannii antimicrobial resistance urinary tract infection community-acquired infections nosocomial infections species identification Peru Antibiotic Resistance in Bacteria Infections and bacterial resistance Bacterial Identification and Susceptibility Testing |
| url | https://doi.org/10.1155/jotm/8851906 |
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