Obsessive-Compulsive Disorder: Emerging
Obsessive-compulsive disorder (OCD) is a chronic and debilitating condition, characterized by obsessions and compulsions that significantly compromise the quality of life of individuals.Despite the effectiveness of conventional treatments, such as selective serotonin reuptake inhibitors (SSRIs) and...
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| Lenguaje: | inglés |
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2025
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| author | Geisiane Cardoso Brandão S. Falconì Vanessa Queiroz Carneiro Tarciso Ferroni Tadei Perla de Lourdes Oliveira Santos Ryan Rafael Barros de Macedo Andreia Dantas Costa Reginaldo Rosa Santos Bruna Feichas Renó Igor Mendes Cardoso Gusthavo Henryque de Araujo Fernando Gomes Costa Paulo Henrique Fugi |
| author_browse | Andreia Dantas Costa Bruna Feichas Renó Fernando Gomes Costa Geisiane Cardoso Brandão Gusthavo Henryque de Araujo Igor Mendes Cardoso Paulo Henrique Fugi Perla de Lourdes Oliveira Santos Reginaldo Rosa Santos Ryan Rafael Barros de Macedo S. Falconì Tarciso Ferroni Tadei Vanessa Queiroz Carneiro |
| author_facet | Geisiane Cardoso Brandão S. Falconì Vanessa Queiroz Carneiro Tarciso Ferroni Tadei Perla de Lourdes Oliveira Santos Ryan Rafael Barros de Macedo Andreia Dantas Costa Reginaldo Rosa Santos Bruna Feichas Renó Igor Mendes Cardoso Gusthavo Henryque de Araujo Fernando Gomes Costa Paulo Henrique Fugi |
| author_sort | Geisiane Cardoso Brandão |
| collection | Producción científica |
| description | Obsessive-compulsive disorder (OCD) is a chronic and debilitating condition, characterized by obsessions and compulsions that significantly compromise the quality of life of individuals.Despite the effectiveness of conventional treatments, such as selective serotonin reuptake inhibitors (SSRIs) and cognitive-behavioral therapy (CBT), a substantial proportion of patients show an unsatisfactory response, constituting cases of resistant OCD.This scenario has led to a search for emerging therapeutic approaches.This literature review analyzed recent publications on new pharmacological strategies, such as the use of glutamatergic modulators (N-acetylcysteine, memantine, riluzole), anti-inflammatories and drugs with new neurobiological mechanisms, as well as neuromodulation techniques and combination therapies.In the psychotherapeutic field, advances in CBT stand out, especially with a focus on inhibitory learning as the central mechanism of exposure with response prevention (EPR).The integration of innovative treatments and therapeutic personalization represent a promising advance in the management of refractory OCD, expanding the possibilities of clinical and functional response in patients. |
| format | Article |
| id | openalex:W4410849366 |
| institution | UPeU |
| language | English |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| record_format | dspace |
| spelling | openalex:W4410849366Obsessive-Compulsive Disorder: EmergingGeisiane Cardoso BrandãoS. FalconìVanessa Queiroz CarneiroTarciso Ferroni TadeiPerla de Lourdes Oliveira SantosRyan Rafael Barros de MacedoAndreia Dantas CostaReginaldo Rosa SantosBruna Feichas RenóIgor Mendes CardosoGusthavo Henryque de AraujoFernando Gomes CostaPaulo Henrique Fugiobsessive-compulsive disordertreatment-resistant OCDN-acetylcysteinememantineriluzoleanti-inflammatory agentsneuromodulationcombination therapycognitive behavioral therapyexposure and response preventioninhibitory learningpersonalized treatmentObsessive-Compulsive Spectrum DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychoanalysis and Psychopathology ResearchObsessive-compulsive disorder (OCD) is a chronic and debilitating condition, characterized by obsessions and compulsions that significantly compromise the quality of life of individuals.Despite the effectiveness of conventional treatments, such as selective serotonin reuptake inhibitors (SSRIs) and cognitive-behavioral therapy (CBT), a substantial proportion of patients show an unsatisfactory response, constituting cases of resistant OCD.This scenario has led to a search for emerging therapeutic approaches.This literature review analyzed recent publications on new pharmacological strategies, such as the use of glutamatergic modulators (N-acetylcysteine, memantine, riluzole), anti-inflammatories and drugs with new neurobiological mechanisms, as well as neuromodulation techniques and combination therapies.In the psychotherapeutic field, advances in CBT stand out, especially with a focus on inhibitory learning as the central mechanism of exposure with response prevention (EPR).The integration of innovative treatments and therapeutic personalization represent a promising advance in the management of refractory OCD, expanding the possibilities of clinical and functional response in patients.Articlehttps://doi.org/10.22533/at.ed.1595232528055https://atenaeditora.com.br/catalogo/dowload-post/97713W4410849366enInternational Journal of Health Science2764-01592025-05-29 |
| spellingShingle | obsessive-compulsive disorder treatment-resistant OCD N-acetylcysteine memantine riluzole anti-inflammatory agents neuromodulation combination therapy cognitive behavioral therapy exposure and response prevention inhibitory learning personalized treatment Obsessive-Compulsive Spectrum Disorders Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Psychoanalysis and Psychopathology Research Geisiane Cardoso Brandão S. Falconì Vanessa Queiroz Carneiro Tarciso Ferroni Tadei Perla de Lourdes Oliveira Santos Ryan Rafael Barros de Macedo Andreia Dantas Costa Reginaldo Rosa Santos Bruna Feichas Renó Igor Mendes Cardoso Gusthavo Henryque de Araujo Fernando Gomes Costa Paulo Henrique Fugi Obsessive-Compulsive Disorder: Emerging |
| title | Obsessive-Compulsive Disorder: Emerging |
| title_full | Obsessive-Compulsive Disorder: Emerging |
| title_fullStr | Obsessive-Compulsive Disorder: Emerging |
| title_full_unstemmed | Obsessive-Compulsive Disorder: Emerging |
| title_short | Obsessive-Compulsive Disorder: Emerging |
| title_sort | obsessive compulsive disorder emerging |
| topic | obsessive-compulsive disorder treatment-resistant OCD N-acetylcysteine memantine riluzole anti-inflammatory agents neuromodulation combination therapy cognitive behavioral therapy exposure and response prevention inhibitory learning personalized treatment Obsessive-Compulsive Spectrum Disorders Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Psychoanalysis and Psychopathology Research |
| topic_facet | obsessive-compulsive disorder treatment-resistant OCD N-acetylcysteine memantine riluzole anti-inflammatory agents neuromodulation combination therapy cognitive behavioral therapy exposure and response prevention inhibitory learning personalized treatment Obsessive-Compulsive Spectrum Disorders Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Psychoanalysis and Psychopathology Research |
| url | https://doi.org/10.22533/at.ed.1595232528055 https://atenaeditora.com.br/catalogo/dowload-post/97713 |
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