ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION
PURPOSE: To describe the natural history of eyes with symptomatic idiopathic vitreomacular traction (VMT). METHODS: Retrospective multicenter study of 168 eyes with spectral-domain optical coherence tomography (SD-OCT) findings consistent with idiopathic VMT. All eyes were graded according to SD-OCT...
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| author | Lihteh Wu Marcelo Zas María H. Berrocal J. Fernando Arévalo Marta S. Figueroa Francisco J. Rodríguez Martín Serrano Federico Graue Arturo Alezzandrini Roberto Gallego‐Pinazo José A. Roca Matías Iglicki José Dalma-Weishauz Igor Kozak Alberto Collado Josep Badal Maurício Maia Guillermo Salcedo-Villanueva Hugo Quiroz-Mercado Jans Fromow-Guerra David Lozano-Rechy Marcos Pereira de Ávila Jay Chhablani |
| author_browse | Alberto Collado Arturo Alezzandrini David Lozano-Rechy Federico Graue Francisco J. Rodríguez Guillermo Salcedo-Villanueva Hugo Quiroz-Mercado Igor Kozak J. Fernando Arévalo Jans Fromow-Guerra Jay Chhablani Josep Badal José A. Roca José Dalma-Weishauz Lihteh Wu Marcelo Zas Marcos Pereira de Ávila Marta S. Figueroa Martín Serrano María H. Berrocal Matías Iglicki Maurício Maia Roberto Gallego‐Pinazo |
| author_facet | Lihteh Wu Marcelo Zas María H. Berrocal J. Fernando Arévalo Marta S. Figueroa Francisco J. Rodríguez Martín Serrano Federico Graue Arturo Alezzandrini Roberto Gallego‐Pinazo José A. Roca Matías Iglicki José Dalma-Weishauz Igor Kozak Alberto Collado Josep Badal Maurício Maia Guillermo Salcedo-Villanueva Hugo Quiroz-Mercado Jans Fromow-Guerra David Lozano-Rechy Marcos Pereira de Ávila Jay Chhablani |
| author_sort | Lihteh Wu |
| collection | Producción científica |
| description | PURPOSE: To describe the natural history of eyes with symptomatic idiopathic vitreomacular traction (VMT). METHODS: Retrospective multicenter study of 168 eyes with spectral-domain optical coherence tomography (SD-OCT) findings consistent with idiopathic VMT. All eyes were graded according to SD-OCT findings. Grade 1 was defined as incomplete cortical vitreous separation with foveal attachment. Grade 2 was defined as Grade 1 plus intraretinal cysts or clefts. Grade 3 was defined as Grade 2 plus a foveal detachment. All patients were followed for at least 6 months. RESULTS: There were 168 patients (51 men) with a mean age of 68.8 ± 10.7 years. Patients were followed for a mean of 22.7 ± 20.1 months. The mean duration of symptoms before the initial presentation was 3.65 ± 5.42 months. At baseline, 72 eyes had Grade 1, 74 eyes had Grade 2, and 22 eyes had Grade 3 SD-OCT findings. Over the follow-up period, 36 eyes (21.4%) had spontaneous resolution of the VMT with normalization of the foveal anatomy. The mean time to resolution was 12.3 ± 12.6 months. An unfavorable anatomical outcome occurred in 7.7% (13 of 168) of the eyes, with 6 eyes developing a lamellar macular hole and 7 eyes developing a full-thickness macular hole. This occurred at a mean of 10.3 ± 10.7 months after the presentation. Subgroup analysis based on baseline SD-OCT grade showed that 4.1% (3 of 73) of Grade 1 eyes compared with 6.8% (5 of 74) of Grade 2 eyes, and 23.8% (5 of 21) of Grade 3 eyes developed a full-thickness macular hole or lamellar macular hole (P = 0.0109, chi-square test). In the remaining 119 eyes, at the last follow-up, 65 eyes had Grade 1, 42 eyes had Grade 2, and 12 eyes had Grade 3 VMT. On average, the best-corrected visual acuity improved from 0.40 ± 0.35 logarithm of the minimum angle of resolution (Snellen, 20/50) at baseline to 0.35 ± 0.36 logarithm of the minimum angle of resolution (Snellen, 20/45; P = 0.0372), and the mean central macular thickness improved from 350 ± 132 μm to 323 ± 121 μm. CONCLUSION: Spontaneous resolution of VMT occurred in 21.4% (36 of 168) of eyes after a mean follow-up of 11.4 ± 12.6 months. An unfavorable anatomical outcome occurred in 7.7% (13 of 168) of eyes. The baseline SD-OCT grade may predict the progression to full-thickness macular hole. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/940 |
| institution | UPeU |
| language | English |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/9402026-10-30T16:15:00ZANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTIONLihteh WuMarcelo ZasMaría H. BerrocalJ. Fernando ArévaloMarta S. FigueroaFrancisco J. RodríguezMartín SerranoFederico GraueArturo AlezzandriniRoberto Gallego‐PinazoJosé A. RocaMatías IglickiJosé Dalma-WeishauzIgor KozakAlberto ColladoJosep BadalMaurício MaiaGuillermo Salcedo-VillanuevaHugo Quiroz-MercadoJans Fromow-GuerraDavid Lozano-RechyMarcos Pereira de ÁvilaJay ChhablaniMedicineMacular holeOphthalmologyFovealOptical coherence tomographyVisual acuityRetrospective cohort studySurgeryRetinalVitrectomyMedicineMacular holeOphthalmologyFovealOptical coherence tomographyVisual acuityRetrospective cohort studySurgeryRetinalVitrectomyTissue Adhesions diagnosisTissue Adhesions diagnosisTissue Adhesions diagnosisAgedAgedAgedFemaleFemaleFemaleFibrinolysin therapeutic useFibrinolysin therapeutic useFibrinolysin therapeutic useFibrinolytic Agents therapeutic useFibrinolytic Agents therapeutic useFibrinolytic Agents therapeutic useHumansHumansHumansMaleMaleMalePeptide Fragments therapeutic usePeptide Fragments therapeutic usePeptide Fragments therapeutic useRemission, SpontaneousRemission, SpontaneousRemission, SpontaneousRetinal Diseases complicationsRetinal Diseases complicationsRetinal Diseases complicationsRetinal Diseases diagnosisRetinal Diseases diagnosisRetinal Diseases diagnosisRetinal Diseases physiopathologyRetinal Diseases physiopathologyRetinal Diseases physiopathologyRetinal Perforations diagnosisRetinal Perforations diagnosisRetinal Perforations diagnosisRetinal Perforations drug therapyRetinal Perforations drug therapyRetinal Perforations drug therapyRetrospective StudiesRetrospective StudiesRetrospective StudiesVisual Acuity physiologyVisual Acuity physiologyVisual Acuity physiologyVitrectomyVitrectomyVitrectomyVitreous Detachment complicationsVitreous Detachment complicationsVitreous Detachment complicationsVitreous Detachment diagnosisVitreous Detachment diagnosisVitreous Detachment diagnosisVitreous Detachment physiopathologyVitreous Detachment physiopathologyVitreous Detachment physiopathologyTomography, Optical CoherenceTomography, Optical CoherenceTomography, Optical CoherenceSlit LampSlit LampSlit LampHealth Sciences Medicine Radiology, Nuclear Medicine and Imaging Retinal and Macular SurgeryHealth Sciences Medicine Ophthalmology Retinal Diseases and TreatmentsHealth Sciences Medicine Ophthalmology Intraocular Surgery and LensesPURPOSE: To describe the natural history of eyes with symptomatic idiopathic vitreomacular traction (VMT). METHODS: Retrospective multicenter study of 168 eyes with spectral-domain optical coherence tomography (SD-OCT) findings consistent with idiopathic VMT. All eyes were graded according to SD-OCT findings. Grade 1 was defined as incomplete cortical vitreous separation with foveal attachment. Grade 2 was defined as Grade 1 plus intraretinal cysts or clefts. Grade 3 was defined as Grade 2 plus a foveal detachment. All patients were followed for at least 6 months. RESULTS: There were 168 patients (51 men) with a mean age of 68.8 ± 10.7 years. Patients were followed for a mean of 22.7 ± 20.1 months. The mean duration of symptoms before the initial presentation was 3.65 ± 5.42 months. At baseline, 72 eyes had Grade 1, 74 eyes had Grade 2, and 22 eyes had Grade 3 SD-OCT findings. Over the follow-up period, 36 eyes (21.4%) had spontaneous resolution of the VMT with normalization of the foveal anatomy. The mean time to resolution was 12.3 ± 12.6 months. An unfavorable anatomical outcome occurred in 7.7% (13 of 168) of the eyes, with 6 eyes developing a lamellar macular hole and 7 eyes developing a full-thickness macular hole. This occurred at a mean of 10.3 ± 10.7 months after the presentation. Subgroup analysis based on baseline SD-OCT grade showed that 4.1% (3 of 73) of Grade 1 eyes compared with 6.8% (5 of 74) of Grade 2 eyes, and 23.8% (5 of 21) of Grade 3 eyes developed a full-thickness macular hole or lamellar macular hole (P = 0.0109, chi-square test). In the remaining 119 eyes, at the last follow-up, 65 eyes had Grade 1, 42 eyes had Grade 2, and 12 eyes had Grade 3 VMT. On average, the best-corrected visual acuity improved from 0.40 ± 0.35 logarithm of the minimum angle of resolution (Snellen, 20/50) at baseline to 0.35 ± 0.36 logarithm of the minimum angle of resolution (Snellen, 20/45; P = 0.0372), and the mean central macular thickness improved from 350 ± 132 μm to 323 ± 121 μm. CONCLUSION: Spontaneous resolution of VMT occurred in 21.4% (36 of 168) of eyes after a mean follow-up of 11.4 ± 12.6 months. An unfavorable anatomical outcome occurred in 7.7% (13 of 168) of eyes. The baseline SD-OCT grade may predict the progression to full-thickness macular hole.Articlehttps://pubmed.ncbi.nlm.nih.gov/26966868https://repository.urosario.edu.co/handle/10336/2293910.1097/iae.0000000000001015https://hdl.handle.net/20.500.15037/940W2341856237enRetina0275-004X1539-28642016-03-112026-06-13T09:41:01Z2026-06-13T09:41:01Z |
| spellingShingle | Medicine Macular hole Ophthalmology Foveal Optical coherence tomography Visual acuity Retrospective cohort study Surgery Retinal Vitrectomy Medicine Macular hole Ophthalmology Foveal Optical coherence tomography Visual acuity Retrospective cohort study Surgery Retinal Vitrectomy Tissue Adhesions diagnosis Tissue Adhesions diagnosis Tissue Adhesions diagnosis Aged Aged Aged Female Female Female Fibrinolysin therapeutic use Fibrinolysin therapeutic use Fibrinolysin therapeutic use Fibrinolytic Agents therapeutic use Fibrinolytic Agents therapeutic use Fibrinolytic Agents therapeutic use Humans Humans Humans Male Male Male Peptide Fragments therapeutic use Peptide Fragments therapeutic use Peptide Fragments therapeutic use Remission, Spontaneous Remission, Spontaneous Remission, Spontaneous Retinal Diseases complications Retinal Diseases complications Retinal Diseases complications Retinal Diseases diagnosis Retinal Diseases diagnosis Retinal Diseases diagnosis Retinal Diseases physiopathology Retinal Diseases physiopathology Retinal Diseases physiopathology Retinal Perforations diagnosis Retinal Perforations diagnosis Retinal Perforations diagnosis Retinal Perforations drug therapy Retinal Perforations drug therapy Retinal Perforations drug therapy Retrospective Studies Retrospective Studies Retrospective Studies Visual Acuity physiology Visual Acuity physiology Visual Acuity physiology Vitrectomy Vitrectomy Vitrectomy Vitreous Detachment complications Vitreous Detachment complications Vitreous Detachment complications Vitreous Detachment diagnosis Vitreous Detachment diagnosis Vitreous Detachment diagnosis Vitreous Detachment physiopathology Vitreous Detachment physiopathology Vitreous Detachment physiopathology Tomography, Optical Coherence Tomography, Optical Coherence Tomography, Optical Coherence Slit Lamp Slit Lamp Slit Lamp Health Sciences Medicine Radiology, Nuclear Medicine and Imaging Retinal and Macular Surgery Health Sciences Medicine Ophthalmology Retinal Diseases and Treatments Health Sciences Medicine Ophthalmology Intraocular Surgery and Lenses Lihteh Wu Marcelo Zas María H. Berrocal J. Fernando Arévalo Marta S. Figueroa Francisco J. Rodríguez Martín Serrano Federico Graue Arturo Alezzandrini Roberto Gallego‐Pinazo José A. Roca Matías Iglicki José Dalma-Weishauz Igor Kozak Alberto Collado Josep Badal Maurício Maia Guillermo Salcedo-Villanueva Hugo Quiroz-Mercado Jans Fromow-Guerra David Lozano-Rechy Marcos Pereira de Ávila Jay Chhablani ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION |
| title | ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION |
| title_full | ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION |
| title_fullStr | ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION |
| title_full_unstemmed | ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION |
| title_short | ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION |
| title_sort | anatomical and functional outcomes of symptomatic idiopathic vitreomacular traction |
| topic | Medicine Macular hole Ophthalmology Foveal Optical coherence tomography Visual acuity Retrospective cohort study Surgery Retinal Vitrectomy Medicine Macular hole Ophthalmology Foveal Optical coherence tomography Visual acuity Retrospective cohort study Surgery Retinal Vitrectomy Tissue Adhesions diagnosis Tissue Adhesions diagnosis Tissue Adhesions diagnosis Aged Aged Aged Female Female Female Fibrinolysin therapeutic use Fibrinolysin therapeutic use Fibrinolysin therapeutic use Fibrinolytic Agents therapeutic use Fibrinolytic Agents therapeutic use Fibrinolytic Agents therapeutic use Humans Humans Humans Male Male Male Peptide Fragments therapeutic use Peptide Fragments therapeutic use Peptide Fragments therapeutic use Remission, Spontaneous Remission, Spontaneous Remission, Spontaneous Retinal Diseases complications Retinal Diseases complications Retinal Diseases complications Retinal Diseases diagnosis Retinal Diseases diagnosis Retinal Diseases diagnosis Retinal Diseases physiopathology Retinal Diseases physiopathology Retinal Diseases physiopathology Retinal Perforations diagnosis Retinal Perforations diagnosis Retinal Perforations diagnosis Retinal Perforations drug therapy Retinal Perforations drug therapy Retinal Perforations drug therapy Retrospective Studies Retrospective Studies Retrospective Studies Visual Acuity physiology Visual Acuity physiology Visual Acuity physiology Vitrectomy Vitrectomy Vitrectomy Vitreous Detachment complications Vitreous Detachment complications Vitreous Detachment complications Vitreous Detachment diagnosis Vitreous Detachment diagnosis Vitreous Detachment diagnosis Vitreous Detachment physiopathology Vitreous Detachment physiopathology Vitreous Detachment physiopathology Tomography, Optical Coherence Tomography, Optical Coherence Tomography, Optical Coherence Slit Lamp Slit Lamp Slit Lamp Health Sciences Medicine Radiology, Nuclear Medicine and Imaging Retinal and Macular Surgery Health Sciences Medicine Ophthalmology Retinal Diseases and Treatments Health Sciences Medicine Ophthalmology Intraocular Surgery and Lenses |
| topic_facet | Medicine Macular hole Ophthalmology Foveal Optical coherence tomography Visual acuity Retrospective cohort study Surgery Retinal Vitrectomy Medicine Macular hole Ophthalmology Foveal Optical coherence tomography Visual acuity Retrospective cohort study Surgery Retinal Vitrectomy Tissue Adhesions diagnosis Tissue Adhesions diagnosis Tissue Adhesions diagnosis Aged Aged Aged Female Female Female Fibrinolysin therapeutic use Fibrinolysin therapeutic use Fibrinolysin therapeutic use Fibrinolytic Agents therapeutic use Fibrinolytic Agents therapeutic use Fibrinolytic Agents therapeutic use Humans Humans Humans Male Male Male Peptide Fragments therapeutic use Peptide Fragments therapeutic use Peptide Fragments therapeutic use Remission, Spontaneous Remission, Spontaneous Remission, Spontaneous Retinal Diseases complications Retinal Diseases complications Retinal Diseases complications Retinal Diseases diagnosis Retinal Diseases diagnosis Retinal Diseases diagnosis Retinal Diseases physiopathology Retinal Diseases physiopathology Retinal Diseases physiopathology Retinal Perforations diagnosis Retinal Perforations diagnosis Retinal Perforations diagnosis Retinal Perforations drug therapy Retinal Perforations drug therapy Retinal Perforations drug therapy Retrospective Studies Retrospective Studies Retrospective Studies Visual Acuity physiology Visual Acuity physiology Visual Acuity physiology Vitrectomy Vitrectomy Vitrectomy Vitreous Detachment complications Vitreous Detachment complications Vitreous Detachment complications Vitreous Detachment diagnosis Vitreous Detachment diagnosis Vitreous Detachment diagnosis Vitreous Detachment physiopathology Vitreous Detachment physiopathology Vitreous Detachment physiopathology Tomography, Optical Coherence Tomography, Optical Coherence Tomography, Optical Coherence Slit Lamp Slit Lamp Slit Lamp Health Sciences Medicine Radiology, Nuclear Medicine and Imaging Retinal and Macular Surgery Health Sciences Medicine Ophthalmology Retinal Diseases and Treatments Health Sciences Medicine Ophthalmology Intraocular Surgery and Lenses |
| url | https://pubmed.ncbi.nlm.nih.gov/26966868 https://repository.urosario.edu.co/handle/10336/22939 https://hdl.handle.net/20.500.15037/940 |
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