Unveiling drug-tolerant and persister-like cells in Leishmania braziliensis lines derived from patients with cutaneous leishmaniasis

Introduction Resistance against anti- Leishmania drugs (DR) has been studied for years, giving important insights into long-term adaptations of these parasites to drugs, through genetic modifications. However, microorganisms can also survive lethal drug exposure by entering into temporary quiescence...

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Autores principales: Marlene Jara, Jorge Arévalo, Alejandro Llanos‐Cuentas, Frederik Van den Broeck, Malgorzata A. Domagalska, Jean‐Claude Dujardin
Formato: Artículo
Lenguaje:inglés
Publicado: 2023
Materias:
Leishmania
Leishmania braziliensis
Biology
Drug
Drug resistance
Cutaneous leishmaniasis
Microbiology
In vitro
Leishmaniasis
Leishmania major
Phenotype
In vivo
Parasite hosting
Immunology
Genetics
Pharmacology
Gene
World Wide Web
Computer science
Humans
Leishmania braziliensis genetics
Leishmaniasis, Cutaneous drug therapy
Leishmaniasis, Cutaneous parasitology
Health Sciences Medicine Public Health, Environmental and Occupational Health Research on Leishmaniasis Studies
Health Sciences Medicine Epidemiology Trypanosoma species research and implications
Life Sciences Agricultural and Biological Sciences Insect Science Insect and Pesticide Research
Acceso en línea:Ver en el sistema de origen
Ver en el sistema de origen
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