Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region
Alterations in dehydroepiandrosterone sulfate (DHEAS) levels have been shown to affect the cardiovascular system. This study examined the associations between DHEAS levels and cardiovascular risk in workers of a public hospital in Lima, Peru. The analytical cross-sectional study was conducted at the...
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2020
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| author | Rojas Humpire, Ricardo Josue Chavez Sosa, Jannett Virginia Gutierrez-Ajalcriña, Rosmery Huancahuire Vega, Salomon |
| author_browse | Chavez Sosa, Jannett Virginia Gutierrez-Ajalcriña, Rosmery Huancahuire Vega, Salomon Rojas Humpire, Ricardo Josue |
| author_facet | Rojas Humpire, Ricardo Josue Chavez Sosa, Jannett Virginia Gutierrez-Ajalcriña, Rosmery Huancahuire Vega, Salomon |
| author_sort | Rojas Humpire, Ricardo Josue |
| collection | Producción científica |
| description | Alterations in dehydroepiandrosterone sulfate (DHEAS) levels have been shown to affect the cardiovascular system. This study examined the associations between DHEAS levels and cardiovascular risk in workers of a public hospital in Lima, Peru. The analytical cross-sectional study was conducted at the Hospital de Huaycán, Peru. The cardiovascular risk was assessed in health workers using the Framingham score and categorized into high and low cardiovascular risk groups, and then the DHEAS levels of both groups were compared. Two hundred ninety-six health workers were studied, 67.2% showed low cardiovascular risk, 22.3% intermediate and 10.5% high. DHEAS levels were lower in the high cardiovascular risk group (2156.9 vs 2814.6 ng/mL; P < 0.05) and showed negative association (prevalence rate ratio 0.14, 95% IC 0.04–0.53; P < 0.05) in multivariable analysis ( P < 0.05). DHEAS, glycosylated hemoglobin, pulse pressure and mean arterial pressure show an independent association with high cardiovascular risk in a group of health workers. Additional variables should be considered for cardiovascular risk assessment. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/772 |
| institution | UPeU |
| language | English |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/7722026-11-02T12:57:04ZAssociation between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian regionRojas Humpire, Ricardo JosueChavez Sosa, Jannett VirginiaGutierrez-Ajalcriña, RosmeryHuancahuire Vega, SalomonCardiovascular diseasesDehydroepiandrosterone sulfaterisk factorsAlterations in dehydroepiandrosterone sulfate (DHEAS) levels have been shown to affect the cardiovascular system. This study examined the associations between DHEAS levels and cardiovascular risk in workers of a public hospital in Lima, Peru. The analytical cross-sectional study was conducted at the Hospital de Huaycán, Peru. The cardiovascular risk was assessed in health workers using the Framingham score and categorized into high and low cardiovascular risk groups, and then the DHEAS levels of both groups were compared. Two hundred ninety-six health workers were studied, 67.2% showed low cardiovascular risk, 22.3% intermediate and 10.5% high. DHEAS levels were lower in the high cardiovascular risk group (2156.9 vs 2814.6 ng/mL; P < 0.05) and showed negative association (prevalence rate ratio 0.14, 95% IC 0.04–0.53; P < 0.05) in multivariable analysis ( P < 0.05). DHEAS, glycosylated hemoglobin, pulse pressure and mean arterial pressure show an independent association with high cardiovascular risk in a group of health workers. Additional variables should be considered for cardiovascular risk assessment.Articlehttps://pubmed.ncbi.nlm.nih.gov/33634256https://doi.org/10.1097/xce.0000000000000219PMC790182610.1097/xce.0000000000000219https://hdl.handle.net/20.500.15037/77233634256W3036750007enCardiovascular Endocrinology & Metabolism2574-09542020-06-192026-06-13T09:34:44Z2026-06-13T09:34:44Z |
| spellingShingle | Cardiovascular diseases Dehydroepiandrosterone sulfate risk factors Rojas Humpire, Ricardo Josue Chavez Sosa, Jannett Virginia Gutierrez-Ajalcriña, Rosmery Huancahuire Vega, Salomon Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region |
| title | Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region |
| title_full | Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region |
| title_fullStr | Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region |
| title_full_unstemmed | Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region |
| title_short | Association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a Peruvian region |
| title_sort | association between dehydroepiandrosterone levels and cardiovascular risk in public sector health workers in a peruvian region |
| topic | Cardiovascular diseases Dehydroepiandrosterone sulfate risk factors |
| topic_facet | Cardiovascular diseases Dehydroepiandrosterone sulfate risk factors |
| url | https://pubmed.ncbi.nlm.nih.gov/33634256 https://doi.org/10.1097/xce.0000000000000219 https://hdl.handle.net/20.500.15037/772 |
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