Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru

We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Disease...

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Autores principales: Galindo-Yllu, Brenda M., Rojas Humpire, Ricardo Josue, Toro‐Huamanchumo, Carlos J., Gutierrez-Ajalcriña, Rosmery, Soriano Moreno, Anderson Nelver Elías
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Publicado: 2021
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author Galindo-Yllu, Brenda M.
Rojas Humpire, Ricardo Josue
Toro‐Huamanchumo, Carlos J.
Gutierrez-Ajalcriña, Rosmery
Soriano Moreno, Anderson Nelver Elías
author_browse Galindo-Yllu, Brenda M.
Gutierrez-Ajalcriña, Rosmery
Rojas Humpire, Ricardo Josue
Soriano Moreno, Anderson Nelver Elías
Toro‐Huamanchumo, Carlos J.
author_facet Galindo-Yllu, Brenda M.
Rojas Humpire, Ricardo Josue
Toro‐Huamanchumo, Carlos J.
Gutierrez-Ajalcriña, Rosmery
Soriano Moreno, Anderson Nelver Elías
author_sort Galindo-Yllu, Brenda M.
collection Producción científica
description We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07-2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population.
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spelling oai:cris.upeu.edu.pe:20.500.15037/5582026-11-02T22:00:04ZSerum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from PeruGalindo-Yllu, Brenda M.Rojas Humpire, Ricardo JosueToro‐Huamanchumo, Carlos J.Gutierrez-Ajalcriña, RosmerySoriano Moreno, Anderson Nelver ElíasWe explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07-2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population.Articlehttps://pubmed.ncbi.nlm.nih.gov/34820139https://downloads.hindawi.com/journals/jnme/2021/9933319.pdfhttps://doi.org/10.1155/2021/9933319PMC860852310.1155/2021/9933319https://hdl.handle.net/20.500.15037/55834820139W3213062175enJournal of Nutrition and Metabolism2090-07242090-07322021-11-152026-06-13T08:17:17Z2026-06-13T08:17:17Z
spellingShingle Galindo-Yllu, Brenda M.
Rojas Humpire, Ricardo Josue
Toro‐Huamanchumo, Carlos J.
Gutierrez-Ajalcriña, Rosmery
Soriano Moreno, Anderson Nelver Elías
Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_full Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_fullStr Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_full_unstemmed Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_short Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru
title_sort serum uric acid is associated with metabolic syndrome and insulin resistance among health personnel from peru
url https://pubmed.ncbi.nlm.nih.gov/34820139
https://downloads.hindawi.com/journals/jnme/2021/9933319.pdf
https://doi.org/10.1155/2021/9933319
https://hdl.handle.net/20.500.15037/558
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