Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli
Urinary infections are caused mainly by Escherichia coli (E. coli); indiscriminate use of antibiotics has caused an increase in infections due to extended-spectrum beta-lactamase (ESBL)-producing strains. Aiming to determine the sensitivity to fosfomycin, a study was conducted in ESBL-producing E. c...
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Instituto Nacional de Salud biomedica@ins.gov.co
2018
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| author | Lifonzo-Mucha, Sheyber J. Tamariz-Zamudio, Paula E. Champi Merino, Roky Govanni |
| author_browse | Champi Merino, Roky Govanni Lifonzo-Mucha, Sheyber J. Tamariz-Zamudio, Paula E. |
| author_facet | Lifonzo-Mucha, Sheyber J. Tamariz-Zamudio, Paula E. Champi Merino, Roky Govanni |
| author_sort | Lifonzo-Mucha, Sheyber J. |
| collection | Producción científica |
| description | Urinary infections are caused mainly by Escherichia coli (E. coli); indiscriminate use of antibiotics has caused an increase in infections due to extended-spectrum beta-lactamase (ESBL)-producing strains. Aiming to determine the sensitivity to fosfomycin, a study was conducted in ESBL-producing E. coli strains isolated from urine cultures at a hospital in Peru. Two hundred and sixty-six (266) strains of E. coli were collected, which were determined by conventional methods to be ESBL- producing. Sensitivity to fosfomycin was determined through minimum inhibitory concentration with the agar dilution method and the diffusion disc method. One hundred and ninety-two (192) (72.2%) strains of ESBL-producing E. coli strains sensitive to Fosfomycin were found. It, therefore, follows that fosfomycin exhibits antimicrobial activity against ESBL-producing E. coli strains and that it could be considered a good treatment option for resistant strains. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/3243 |
| institution | UPeU |
| language | Spanish |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | Instituto Nacional de Salud biomedica@ins.gov.co |
| publisherStr | Instituto Nacional de Salud biomedica@ins.gov.co |
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| spelling | oai:cris.upeu.edu.pe:20.500.15037/32432026-10-30T17:10:13ZSensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coliSensibilidad a fosfomicina en Escherichia coli productoras de betalactamasas de espectro extendidoLifonzo-Mucha, Sheyber J.Tamariz-Zamudio, Paula E.Champi Merino, Roky Govanniescherichia colibetalactamasasfosfomicinainfección urinariaUrinary infections are caused mainly by Escherichia coli (E. coli); indiscriminate use of antibiotics has caused an increase in infections due to extended-spectrum beta-lactamase (ESBL)-producing strains. Aiming to determine the sensitivity to fosfomycin, a study was conducted in ESBL-producing E. coli strains isolated from urine cultures at a hospital in Peru. Two hundred and sixty-six (266) strains of E. coli were collected, which were determined by conventional methods to be ESBL- producing. Sensitivity to fosfomycin was determined through minimum inhibitory concentration with the agar dilution method and the diffusion disc method. One hundred and ninety-two (192) (72.2%) strains of ESBL-producing E. coli strains sensitive to Fosfomycin were found. It, therefore, follows that fosfomycin exhibits antimicrobial activity against ESBL-producing E. coli strains and that it could be considered a good treatment option for resistant strains.Article10.17843/rpmesp.2018.351.35662-s2.0-85047801167https://hdl.handle.net/20.500.15037/3243esRevista Peruana de Medicina Experimental y Salud PúblicaRevista Peruana de Medicina Experimental y Salud Publica1726-4634Instituto Nacional de Salud biomedica@ins.gov.co2018-03-232026-06-27T02:36:42Z2026-06-27T02:36:42Z |
| spellingShingle | escherichia coli betalactamasas fosfomicina infección urinaria Lifonzo-Mucha, Sheyber J. Tamariz-Zamudio, Paula E. Champi Merino, Roky Govanni Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli |
| title | Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli |
| title_full | Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli |
| title_fullStr | Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli |
| title_full_unstemmed | Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli |
| title_short | Sensitivity to fosfomycin in extended-spectrum beta-lactamase-producing Escherichia coli |
| title_sort | sensitivity to fosfomycin in extended spectrum beta lactamase producing escherichia coli |
| topic | escherichia coli betalactamasas fosfomicina infección urinaria |
| topic_facet | escherichia coli betalactamasas fosfomicina infección urinaria |
| url | https://hdl.handle.net/20.500.15037/3243 |
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