Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis

Objective The objective of this systematic review and meta-analysis was to assess the prevalence of hypertension in populations living at altitude in Latin America and the Caribbean. Methods We conducted a systematic search from January 1, 2000 to January 10, 2023 in Web of Science (WoS)/Core Collec...

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Autores principales: Zila-Velasque, J. Pierre, Soriano Moreno, David, Medina Ramirez, Sebastian Andre, Ccami-Bernal, Fabricio, Castro Diaz, Sharong Dayan, Cortez-Soto, Andrea G., Esparza-Varas, Analis L., Fernandez-Morales, Jared, Olortegui Rodriguez, Juan José, Pelayo Luis, Isabel Pilar, Zafra-Tanaka, Jessica Hanae
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Publicado: Public Library of Science 2023
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author Zila-Velasque, J. Pierre
Soriano Moreno, David
Medina Ramirez, Sebastian Andre
Ccami-Bernal, Fabricio
Castro Diaz, Sharong Dayan
Cortez-Soto, Andrea G.
Esparza-Varas, Analis L.
Fernandez-Morales, Jared
Olortegui Rodriguez, Juan José
Pelayo Luis, Isabel Pilar
Zafra-Tanaka, Jessica Hanae
author_browse Castro Diaz, Sharong Dayan
Ccami-Bernal, Fabricio
Cortez-Soto, Andrea G.
Esparza-Varas, Analis L.
Fernandez-Morales, Jared
Medina Ramirez, Sebastian Andre
Olortegui Rodriguez, Juan José
Pelayo Luis, Isabel Pilar
Soriano Moreno, David
Zafra-Tanaka, Jessica Hanae
Zila-Velasque, J. Pierre
author_facet Zila-Velasque, J. Pierre
Soriano Moreno, David
Medina Ramirez, Sebastian Andre
Ccami-Bernal, Fabricio
Castro Diaz, Sharong Dayan
Cortez-Soto, Andrea G.
Esparza-Varas, Analis L.
Fernandez-Morales, Jared
Olortegui Rodriguez, Juan José
Pelayo Luis, Isabel Pilar
Zafra-Tanaka, Jessica Hanae
author_sort Zila-Velasque, J. Pierre
collection Producción científica
description Objective The objective of this systematic review and meta-analysis was to assess the prevalence of hypertension in populations living at altitude in Latin America and the Caribbean. Methods We conducted a systematic search from January 1, 2000 to January 10, 2023 in Web of Science (WoS)/Core Collection, WoS/Medline, WoS/Scielo, Scopus, PubMed and Embase databases. We included studies that assessed the prevalence of hypertension in altitude populations (>1500 m.a.s.l.) and these were meta-analyzed using a random-effects model. To assess the sources of heterogeneity, we performed subgroup and meta-regression analyses. Results Thirty cross-sectional studies (117 406 participants) met the inclusion criteria. Studies used different cut-off points. The prevalence of hypertension in the studies that considered the cut-off point of ≥ 140/90 mmHg in the general population was 19.1%, ≥ 130/85 mmHg was 13.1%, and ≥ 130/80 mmHg was 43.4%. There was a tendency for the prevalence of hypertension to be higher in men. In meta-regression analyses, no association was found between altitude, mean age, year of publication, risk of bias and prevalence of hypertension. Conclusion The prevalence of hypertension in the altitude population of Latin America and the Caribbean is lower than that reported in populations living at sea level and lower than other altitude populations such as Tibetans. PROSPERO <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021275229" xlink:type="simple">CRD42021275229</jats:ext-link>.
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spelling oai:cris.upeu.edu.pe:20.500.15037/29852026-11-02T22:00:04ZPrevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysisZila-Velasque, J. PierreSoriano Moreno, DavidMedina Ramirez, Sebastian AndreCcami-Bernal, FabricioCastro Diaz, Sharong DayanCortez-Soto, Andrea G.Esparza-Varas, Analis L.Fernandez-Morales, JaredOlortegui Rodriguez, Juan JoséPelayo Luis, Isabel PilarZafra-Tanaka, Jessica HanaeObjective The objective of this systematic review and meta-analysis was to assess the prevalence of hypertension in populations living at altitude in Latin America and the Caribbean. Methods We conducted a systematic search from January 1, 2000 to January 10, 2023 in Web of Science (WoS)/Core Collection, WoS/Medline, WoS/Scielo, Scopus, PubMed and Embase databases. We included studies that assessed the prevalence of hypertension in altitude populations (>1500 m.a.s.l.) and these were meta-analyzed using a random-effects model. To assess the sources of heterogeneity, we performed subgroup and meta-regression analyses. Results Thirty cross-sectional studies (117 406 participants) met the inclusion criteria. Studies used different cut-off points. The prevalence of hypertension in the studies that considered the cut-off point of ≥ 140/90 mmHg in the general population was 19.1%, ≥ 130/85 mmHg was 13.1%, and ≥ 130/80 mmHg was 43.4%. There was a tendency for the prevalence of hypertension to be higher in men. In meta-regression analyses, no association was found between altitude, mean age, year of publication, risk of bias and prevalence of hypertension. Conclusion The prevalence of hypertension in the altitude population of Latin America and the Caribbean is lower than that reported in populations living at sea level and lower than other altitude populations such as Tibetans. PROSPERO <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021275229" xlink:type="simple">CRD42021275229</jats:ext-link>.Article10.1371/journal.pone.02921112-s2.0-85174195744https://hdl.handle.net/20.500.15037/2985enPLoS ONEPLoS ONE1932-6203Public Library of Science2023-10-122026-06-27T02:35:09Z2026-06-27T02:35:09Z
spellingShingle Zila-Velasque, J. Pierre
Soriano Moreno, David
Medina Ramirez, Sebastian Andre
Ccami-Bernal, Fabricio
Castro Diaz, Sharong Dayan
Cortez-Soto, Andrea G.
Esparza-Varas, Analis L.
Fernandez-Morales, Jared
Olortegui Rodriguez, Juan José
Pelayo Luis, Isabel Pilar
Zafra-Tanaka, Jessica Hanae
Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis
title Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis
title_full Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis
title_fullStr Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis
title_full_unstemmed Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis
title_short Prevalence of hypertension in adults living at altitude in Latin America and the Caribbean: A systematic review and meta-analysis
title_sort prevalence of hypertension in adults living at altitude in latin america and the caribbean a systematic review and meta analysis
url https://hdl.handle.net/20.500.15037/2985
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