Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis
Importance: Corticosteroids are recommended as first-line treatment for adults with acute Bell’s palsy, but their role in children remains uncertain. Objective: To assess the effect of corticosteroid therapy on recovery rates in children with acute Bell’s palsy. Evidence Review: PubMed, Scopus, and...
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Mary Ann Liebert Inc.
2025
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| author | Peralta Berrios, Fabian Morales-Puebla, José Manuel Pati, Roman Miralda Matute, Francis Evilda Gavilan Bouzas, Javier Lassaletta, Luis M. |
| author_browse | Gavilan Bouzas, Javier Lassaletta, Luis M. Miralda Matute, Francis Evilda Morales-Puebla, José Manuel Pati, Roman Peralta Berrios, Fabian |
| author_facet | Peralta Berrios, Fabian Morales-Puebla, José Manuel Pati, Roman Miralda Matute, Francis Evilda Gavilan Bouzas, Javier Lassaletta, Luis M. |
| author_sort | Peralta Berrios, Fabian |
| collection | Producción científica |
| description | Importance: Corticosteroids are recommended as first-line treatment for adults with acute Bell’s palsy, but their role in children remains uncertain. Objective: To assess the effect of corticosteroid therapy on recovery rates in children with acute Bell’s palsy. Evidence Review: PubMed, Scopus, and Cochrane Library were systematically searched from inception to April 2, 2025, for studies on corticosteroids for children with Bell’s palsy. Odds ratios and risk ratios with 95% confidence intervals were pooled using R software (version 4.2.3). Risk of bias was assessed with RoB2 and ROBINS-I. Findings: Eleven studies were included, comprising 750 children, of whom 495 (66%) received corticosteroids. The analysis across final follow-ups showed no significant difference. Because follow-ups ranged from 1 to 24 months, 1, 3, and 6 months were used as key points to create comparable intervals. The following subgroups were analyzed for each interval: corticosteroid monotherapy and corticosteroids plus adjunctive therapy. Corticosteroid monotherapy was associated with higher complete recovery rates beyond 1 month and a lower risk of incomplete recovery after 6 months. Conclusions and Relevance: Corticosteroid monotherapy in children with acute Bell’s palsy may improve recovery rates beyond the first month, supporting its implementation in treatment protocols. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/2881 |
| institution | UPeU |
| language | English |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Mary Ann Liebert Inc. |
| publisherStr | Mary Ann Liebert Inc. |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/28812026-11-02T22:00:04ZUse of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-AnalysisPeralta Berrios, FabianMorales-Puebla, José ManuelPati, RomanMiralda Matute, Francis EvildaGavilan Bouzas, JavierLassaletta, Luis M.Importance: Corticosteroids are recommended as first-line treatment for adults with acute Bell’s palsy, but their role in children remains uncertain. Objective: To assess the effect of corticosteroid therapy on recovery rates in children with acute Bell’s palsy. Evidence Review: PubMed, Scopus, and Cochrane Library were systematically searched from inception to April 2, 2025, for studies on corticosteroids for children with Bell’s palsy. Odds ratios and risk ratios with 95% confidence intervals were pooled using R software (version 4.2.3). Risk of bias was assessed with RoB2 and ROBINS-I. Findings: Eleven studies were included, comprising 750 children, of whom 495 (66%) received corticosteroids. The analysis across final follow-ups showed no significant difference. Because follow-ups ranged from 1 to 24 months, 1, 3, and 6 months were used as key points to create comparable intervals. The following subgroups were analyzed for each interval: corticosteroid monotherapy and corticosteroids plus adjunctive therapy. Corticosteroid monotherapy was associated with higher complete recovery rates beyond 1 month and a lower risk of incomplete recovery after 6 months. Conclusions and Relevance: Corticosteroid monotherapy in children with acute Bell’s palsy may improve recovery rates beyond the first month, supporting its implementation in treatment protocols.Article10.1177/268936142513943882-s2.0-105022735940https://hdl.handle.net/20.500.15037/2881enFacial Plastic Surgery & Aesthetic MedicineFacial Plastic Surgery and Aesthetic Medicine2689-3614Mary Ann Liebert Inc.2025-11-122026-06-27T02:34:30Z2026-06-27T02:34:30Z |
| spellingShingle | Peralta Berrios, Fabian Morales-Puebla, José Manuel Pati, Roman Miralda Matute, Francis Evilda Gavilan Bouzas, Javier Lassaletta, Luis M. Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis |
| title | Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis |
| title_full | Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis |
| title_fullStr | Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis |
| title_short | Use of Corticosteroids in Children with Bell’s Palsy: A Systematic Review and Meta-Analysis |
| title_sort | use of corticosteroids in children with bell s palsy a systematic review and meta analysis |
| url | https://hdl.handle.net/20.500.15037/2881 |
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