Novel Biomarkers for the diagnosis of diabetic nephropathy.

Diabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic...

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Autores principales: Marcio Concepción, Juan Carlos Quiroz, Jacsel Suárez, José Enrique López Paz, Pela J Roseboom, Sofia Ildefonso, Denis Cribilleros, Francisca Zavaleta, Julia Arroyo, Luis Concepción
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Publicado: 2024
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author Marcio Concepción
Juan Carlos Quiroz
Jacsel Suárez
José Enrique López Paz
Pela J Roseboom
Sofia Ildefonso
Denis Cribilleros
Francisca Zavaleta
Julia Arroyo
Luis Concepción
author_browse Denis Cribilleros
Francisca Zavaleta
Jacsel Suárez
José Enrique López Paz
Juan Carlos Quiroz
Julia Arroyo
Luis Concepción
Marcio Concepción
Pela J Roseboom
Sofia Ildefonso
author_facet Marcio Concepción
Juan Carlos Quiroz
Jacsel Suárez
José Enrique López Paz
Pela J Roseboom
Sofia Ildefonso
Denis Cribilleros
Francisca Zavaleta
Julia Arroyo
Luis Concepción
author_sort Marcio Concepción
collection Producción científica
description Diabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic inflammation that led to glomerular and tubulo-interstitial damage producing mesangial expansion and glomerulosclerosis, which finally results in chronic kidney disease. Early detection of diabetic nephropathy is essential for adequate intervention to stop, or at least slow down its progression. Multiple markers have been described, not only the classic ones such as serum creatinine, urea, and albuminuria, but at this point also novel biomarkers such as neutrophil gelatinase-associated lipocalin, tumor necrosis factor 1 receptor and monocyte chemoattractant protein-1, among others. The aim of this article was to provide an update review of the role of biomarkers in the diagnosis of diabetic nephropathy.
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spelling oai:cris.upeu.edu.pe:20.500.15037/17702026-10-30T16:16:44ZNovel Biomarkers for the diagnosis of diabetic nephropathy.Marcio ConcepciónJuan Carlos QuirozJacsel SuárezJosé Enrique López PazPela J RoseboomSofia IldefonsoDenis CribillerosFrancisca ZavaletaJulia ArroyoLuis ConcepciónMedicineDiabetic nephropathyDiabetes mellitusDermatologyPathologyRadiologyUrologyInternal medicineEndocrinologyMedicineDiabetic nephropathyDiabetes mellitusDermatologyPathologyRadiologyUrologyInternal medicineEndocrinologyHealth Sciences Medicine Nephrology Chronic Kidney Disease and DiabetesDiabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic inflammation that led to glomerular and tubulo-interstitial damage producing mesangial expansion and glomerulosclerosis, which finally results in chronic kidney disease. Early detection of diabetic nephropathy is essential for adequate intervention to stop, or at least slow down its progression. Multiple markers have been described, not only the classic ones such as serum creatinine, urea, and albuminuria, but at this point also novel biomarkers such as neutrophil gelatinase-associated lipocalin, tumor necrosis factor 1 receptor and monocyte chemoattractant protein-1, among others. The aim of this article was to provide an update review of the role of biomarkers in the diagnosis of diabetic nephropathy.Otherhttps://pubmed.ncbi.nlm.nih.gov/39011442https://pmc.ncbi.nlm.nih.gov/articles/PMC11246682/pdf/cjim-15-382.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/1124668210.22088/cjim.15.3.382https://hdl.handle.net/20.500.15037/1770W4400702591en2024-01-012026-06-13T14:22:24Z2026-06-13T14:22:24Z
spellingShingle Medicine
Diabetic nephropathy
Diabetes mellitus
Dermatology
Pathology
Radiology
Urology
Internal medicine
Endocrinology
Medicine
Diabetic nephropathy
Diabetes mellitus
Dermatology
Pathology
Radiology
Urology
Internal medicine
Endocrinology
Health Sciences Medicine Nephrology Chronic Kidney Disease and Diabetes
Marcio Concepción
Juan Carlos Quiroz
Jacsel Suárez
José Enrique López Paz
Pela J Roseboom
Sofia Ildefonso
Denis Cribilleros
Francisca Zavaleta
Julia Arroyo
Luis Concepción
Novel Biomarkers for the diagnosis of diabetic nephropathy.
title Novel Biomarkers for the diagnosis of diabetic nephropathy.
title_full Novel Biomarkers for the diagnosis of diabetic nephropathy.
title_fullStr Novel Biomarkers for the diagnosis of diabetic nephropathy.
title_full_unstemmed Novel Biomarkers for the diagnosis of diabetic nephropathy.
title_short Novel Biomarkers for the diagnosis of diabetic nephropathy.
title_sort novel biomarkers for the diagnosis of diabetic nephropathy
topic Medicine
Diabetic nephropathy
Diabetes mellitus
Dermatology
Pathology
Radiology
Urology
Internal medicine
Endocrinology
Medicine
Diabetic nephropathy
Diabetes mellitus
Dermatology
Pathology
Radiology
Urology
Internal medicine
Endocrinology
Health Sciences Medicine Nephrology Chronic Kidney Disease and Diabetes
topic_facet Medicine
Diabetic nephropathy
Diabetes mellitus
Dermatology
Pathology
Radiology
Urology
Internal medicine
Endocrinology
Medicine
Diabetic nephropathy
Diabetes mellitus
Dermatology
Pathology
Radiology
Urology
Internal medicine
Endocrinology
Health Sciences Medicine Nephrology Chronic Kidney Disease and Diabetes
url https://pubmed.ncbi.nlm.nih.gov/39011442
https://pmc.ncbi.nlm.nih.gov/articles/PMC11246682/pdf/cjim-15-382.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/11246682
https://hdl.handle.net/20.500.15037/1770
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