Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru
Mucormycosis has been reported increasingly in patients affected by COVID-19, especially in India where the first cases were described. In Latin America, there is limited information about this association, mainly coming from Brazil, Mexico, and Peru. Herein, we report the case of a 66-year-old fema...
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| Formato: | Artículo |
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2022
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| _version_ | 1881508822422388736 |
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| author | Ponce-Rosas, Linda Gonzales-Zamora, Jose Diaz Reyes, Nelson Fidel Alarco-Cadillo, Oliver Alave Rosas, Jorge Luis |
| author_browse | Alarco-Cadillo, Oliver Alave Rosas, Jorge Luis Diaz Reyes, Nelson Fidel Gonzales-Zamora, Jose Ponce-Rosas, Linda |
| author_facet | Ponce-Rosas, Linda Gonzales-Zamora, Jose Diaz Reyes, Nelson Fidel Alarco-Cadillo, Oliver Alave Rosas, Jorge Luis |
| author_sort | Ponce-Rosas, Linda |
| collection | Producción científica |
| description | Mucormycosis has been reported increasingly in patients affected by COVID-19, especially in India where the first cases were described. In Latin America, there is limited information about this association, mainly coming from Brazil, Mexico, and Peru. Herein, we report the case of a 66-year-old female that presented with rhino-orbital-cerebral mucormycosis, diabetic ketoacidosis, and COVID-19. The patient had the compromise of all the sinuses, orbital invasion, and intracranial extension. Isavuconazole was promptly initiated because amphotericin B was not available. She had a single open surgical debridement of necrotic tissues at the beginning of the diagnosis then multiple manual sessions to clear the residual or recurrent disease during approximately 5 months. Isavuconazole was effective and well-tolerated for 10 months without side effects. We highlight the importance of considering mucormycosis in post-COVID-19 patients with uncontrolled diabetes. The report emphasizes the favorable outcome of isavuconazole as an alternative therapy. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/173 |
| institution | UPeU |
| language | English |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
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| spelling | oai:cris.upeu.edu.pe:20.500.15037/1732026-11-02T22:00:04ZRhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from PeruPonce-Rosas, LindaGonzales-Zamora, JoseDiaz Reyes, Nelson FidelAlarco-Cadillo, OliverAlave Rosas, Jorge LuisMucormycosis has been reported increasingly in patients affected by COVID-19, especially in India where the first cases were described. In Latin America, there is limited information about this association, mainly coming from Brazil, Mexico, and Peru. Herein, we report the case of a 66-year-old female that presented with rhino-orbital-cerebral mucormycosis, diabetic ketoacidosis, and COVID-19. The patient had the compromise of all the sinuses, orbital invasion, and intracranial extension. Isavuconazole was promptly initiated because amphotericin B was not available. She had a single open surgical debridement of necrotic tissues at the beginning of the diagnosis then multiple manual sessions to clear the residual or recurrent disease during approximately 5 months. Isavuconazole was effective and well-tolerated for 10 months without side effects. We highlight the importance of considering mucormycosis in post-COVID-19 patients with uncontrolled diabetes. The report emphasizes the favorable outcome of isavuconazole as an alternative therapy.Articlehttps://pubmed.ncbi.nlm.nih.gov/35299936https://downloads.hindawi.com/journals/criid/2022/2537186.pdfhttps://doi.org/10.1155/2022/2537186PMC892214810.1155/2022/2537186https://hdl.handle.net/20.500.15037/17335299936W4220793268enCase Reports in Infectious Diseases2090-66252090-66332022-03-152026-06-13T07:48:54Z2026-06-13T07:48:54Z |
| spellingShingle | Ponce-Rosas, Linda Gonzales-Zamora, Jose Diaz Reyes, Nelson Fidel Alarco-Cadillo, Oliver Alave Rosas, Jorge Luis Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru |
| title | Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru |
| title_full | Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru |
| title_fullStr | Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru |
| title_full_unstemmed | Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru |
| title_short | Rhino-Orbital-Cerebral Mucormycosis in a Post-COVID-19 Patient from Peru |
| title_sort | rhino orbital cerebral mucormycosis in a post covid 19 patient from peru |
| url | https://pubmed.ncbi.nlm.nih.gov/35299936 https://downloads.hindawi.com/journals/criid/2022/2537186.pdf https://doi.org/10.1155/2022/2537186 https://hdl.handle.net/20.500.15037/173 |
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