Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru
Objective To evaluate the factors associated with the intention to participate in COVID-19 vaccine clinical trials in the Peruvian population. Methods Cross-sectional study and secondary analysis of a database that involved Peruvian population during September 2020. The Poisson regression model was...
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2022
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| author | De-Los-Rios-Pinto, Abraham Fernandez‐Guzman, Daniel Soriano‐Moreno, David R. Sangster-Carrasco, Lucero Morocho-Alburqueque, Noelia Pinedo-Soria, Antony Murrieta-Ruiz, Valentina Diaz-Corrales, Angelica Alave Rosas, Jorge Luis Nieto-Gutierrez, Wendy Gonzales-Zamora, Jose |
| author_browse | Alave Rosas, Jorge Luis De-Los-Rios-Pinto, Abraham Diaz-Corrales, Angelica Fernandez‐Guzman, Daniel Gonzales-Zamora, Jose Morocho-Alburqueque, Noelia Murrieta-Ruiz, Valentina Nieto-Gutierrez, Wendy Pinedo-Soria, Antony Sangster-Carrasco, Lucero Soriano‐Moreno, David R. |
| author_facet | De-Los-Rios-Pinto, Abraham Fernandez‐Guzman, Daniel Soriano‐Moreno, David R. Sangster-Carrasco, Lucero Morocho-Alburqueque, Noelia Pinedo-Soria, Antony Murrieta-Ruiz, Valentina Diaz-Corrales, Angelica Alave Rosas, Jorge Luis Nieto-Gutierrez, Wendy Gonzales-Zamora, Jose |
| author_sort | De-Los-Rios-Pinto, Abraham |
| collection | Producción científica |
| description | Objective To evaluate the factors associated with the intention to participate in COVID-19 vaccine clinical trials in the Peruvian population. Methods Cross-sectional study and secondary analysis of a database that involved Peruvian population during September 2020. The Poisson regression model was used to estimate the associated factors. Results Data from 3231 individuals were analyzed, 44.1% of whom intended to participate in COVID-19 vaccine clinical trials. Factors associated with the outcome were being male (RPa: 1.25; 95% CI: 1.15-1.35), being from the highlands region (RPa: 1.18; 95% CI: 1.09-1.28) or jungle (RPa: 1.30; 95% CI: 1.15-1.47), having a relative that is a healthcare professional (PRa: 1.16; 95% CI: 1.06-1.28), using a medical source of information (PRa: 1.28; 95% CI: 1.17-1.41), and trusting in the possible effectiveness of vaccines (PRa: 1.40; 95% CI: 1.29-1.51). The main reason for not participating in the trial was the possibility of developing side effects (69.80%). Conclusion There is an urgent need to generate a perception of safety in COVID-19 vaccine clinical trials, to increase the population's intention to participate in these studies, and to provide evidence-based information about the vaccine. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/172 |
| institution | UPeU |
| language | English |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
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| spelling | oai:cris.upeu.edu.pe:20.500.15037/1722026-11-02T12:57:04ZFactors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in PeruDe-Los-Rios-Pinto, AbrahamFernandez‐Guzman, DanielSoriano‐Moreno, David R.Sangster-Carrasco, LuceroMorocho-Alburqueque, NoeliaPinedo-Soria, AntonyMurrieta-Ruiz, ValentinaDiaz-Corrales, AngelicaAlave Rosas, Jorge LuisNieto-Gutierrez, WendyGonzales-Zamora, JoseVaccineCoronavirusClinical TrialAssociated FactorsIntention To ParticipateCovid-19Objective To evaluate the factors associated with the intention to participate in COVID-19 vaccine clinical trials in the Peruvian population. Methods Cross-sectional study and secondary analysis of a database that involved Peruvian population during September 2020. The Poisson regression model was used to estimate the associated factors. Results Data from 3231 individuals were analyzed, 44.1% of whom intended to participate in COVID-19 vaccine clinical trials. Factors associated with the outcome were being male (RPa: 1.25; 95% CI: 1.15-1.35), being from the highlands region (RPa: 1.18; 95% CI: 1.09-1.28) or jungle (RPa: 1.30; 95% CI: 1.15-1.47), having a relative that is a healthcare professional (PRa: 1.16; 95% CI: 1.06-1.28), using a medical source of information (PRa: 1.28; 95% CI: 1.17-1.41), and trusting in the possible effectiveness of vaccines (PRa: 1.40; 95% CI: 1.29-1.51). The main reason for not participating in the trial was the possibility of developing side effects (69.80%). Conclusion There is an urgent need to generate a perception of safety in COVID-19 vaccine clinical trials, to increase the population's intention to participate in these studies, and to provide evidence-based information about the vaccine.Articlehttps://pubmed.ncbi.nlm.nih.gov/35589452https://www.ncbi.nlm.nih.gov/pmc/articles/8986477PMC898647710.1016/j.vaccine.2022.04.003https://hdl.handle.net/20.500.15037/17235589452W4226174485enVaccine0264-410X1873-25182022-04-072026-06-13T07:48:53Z2026-06-13T07:48:53Z |
| spellingShingle | Vaccine Coronavirus Clinical Trial Associated Factors Intention To Participate Covid-19 De-Los-Rios-Pinto, Abraham Fernandez‐Guzman, Daniel Soriano‐Moreno, David R. Sangster-Carrasco, Lucero Morocho-Alburqueque, Noelia Pinedo-Soria, Antony Murrieta-Ruiz, Valentina Diaz-Corrales, Angelica Alave Rosas, Jorge Luis Nieto-Gutierrez, Wendy Gonzales-Zamora, Jose Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru |
| title | Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru |
| title_full | Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru |
| title_fullStr | Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru |
| title_full_unstemmed | Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru |
| title_short | Factors associated with the intention to participate in COVID-19 vaccine clinical trials: A cross-sectional study in Peru |
| title_sort | factors associated with the intention to participate in covid 19 vaccine clinical trials a cross sectional study in peru |
| topic | Vaccine Coronavirus Clinical Trial Associated Factors Intention To Participate Covid-19 |
| topic_facet | Vaccine Coronavirus Clinical Trial Associated Factors Intention To Participate Covid-19 |
| url | https://pubmed.ncbi.nlm.nih.gov/35589452 https://www.ncbi.nlm.nih.gov/pmc/articles/8986477 https://hdl.handle.net/20.500.15037/172 |
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