Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage
Hepatic alcohol dehydrogenase was measured in liver homogenates from normal, moderate drinkers, and from alcoholics with normal livers, steatosis, and liver cirrhosis. Hepatic alcohol-dehydrogenase activity was 0.37±0.12 µM/hr./mg. of protein in the normals, 0.18±0.13 µM/hr/mg. in alcoholics with no...
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| Formato: | Artículo |
| Lenguaje: | inglés |
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1967
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| _version_ | 1881508965357977600 |
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| author | G Ugarte María Eugenia Pino I Insunza |
| author_browse | G Ugarte I Insunza María Eugenia Pino |
| author_facet | G Ugarte María Eugenia Pino I Insunza |
| author_sort | G Ugarte |
| collection | Producción científica |
| description | Hepatic alcohol dehydrogenase was measured in liver homogenates from normal, moderate drinkers, and from alcoholics with normal livers, steatosis, and liver cirrhosis. Hepatic alcohol-dehydrogenase activity was 0.37±0.12 µM/hr./mg. of protein in the normals, 0.18±0.13 µM/hr/mg. in alcoholics with normal liver histology, 0.12±0.09 µM/hr./mg. in alcoholics with fatty liver, and 0.12±0.08 µM/hr./mg. in patients with alcoholic cirrhosis. Alcohol dehydrogenase was significantly lower among alcoholics. There was no difference in the activity of this enzyme between alcoholic patients with liver damage and those without liver damage. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/1711 |
| institution | UPeU |
| language | English |
| publishDate | 1967 |
| publishDateRange | 1967 |
| publishDateSort | 1967 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/17112026-11-02T22:34:06ZHepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damageG UgarteMaría Eugenia PinoI InsunzaAlcohol dehydrogenaseSteatosisAlcoholic liver diseaseInternal medicineAlcoholic fatty liverFatty liverCirrhosisAlcoholMedicineEthanolGastroenterologyAlcoholic hepatitisEndocrinologyChemistryBiochemistryDiseaseAlcohol dehydrogenaseSteatosisAlcoholic liver diseaseInternal medicineAlcoholic fatty liverFatty liverCirrhosisAlcoholMedicineEthanolGastroenterologyAlcoholic hepatitisEndocrinologyChemistryBiochemistryDiseaseAlcohol Oxidoreductases analysisAlcohol Oxidoreductases analysisAlcohol Oxidoreductases analysisAlcohol Oxidoreductases metabolismAlcohol Oxidoreductases metabolismAlcohol Oxidoreductases metabolismAlcoholism metabolismAlcoholism metabolismAlcoholism metabolismBiopsyBiopsyBiopsyFatty Liver metabolismFatty Liver metabolismFatty Liver metabolismHumansHumansHumansLiver enzymologyLiver enzymologyLiver enzymologyLiver Cirrhosis metabolismLiver Cirrhosis metabolismLiver Cirrhosis metabolismHealth Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health EffectsHealth Sciences Medicine Epidemiology Liver Disease Diagnosis and TreatmentHealth Sciences Medicine Endocrinology, Diabetes and Metabolism Diet, Metabolism, and DiseaseHepatic alcohol dehydrogenase was measured in liver homogenates from normal, moderate drinkers, and from alcoholics with normal livers, steatosis, and liver cirrhosis. Hepatic alcohol-dehydrogenase activity was 0.37±0.12 µM/hr./mg. of protein in the normals, 0.18±0.13 µM/hr/mg. in alcoholics with normal liver histology, 0.12±0.09 µM/hr./mg. in alcoholics with fatty liver, and 0.12±0.08 µM/hr./mg. in patients with alcoholic cirrhosis. Alcohol dehydrogenase was significantly lower among alcoholics. There was no difference in the activity of this enzyme between alcoholic patients with liver damage and those without liver damage.Articlehttps://pubmed.ncbi.nlm.nih.gov/602758910.1007/bf02233496https://hdl.handle.net/20.500.15037/1711W2051482239enDigestive Diseases and Sciences0163-21161573-25681967-06-012026-06-13T14:19:28Z2026-06-13T14:19:28Z |
| spellingShingle | Alcohol dehydrogenase Steatosis Alcoholic liver disease Internal medicine Alcoholic fatty liver Fatty liver Cirrhosis Alcohol Medicine Ethanol Gastroenterology Alcoholic hepatitis Endocrinology Chemistry Biochemistry Disease Alcohol dehydrogenase Steatosis Alcoholic liver disease Internal medicine Alcoholic fatty liver Fatty liver Cirrhosis Alcohol Medicine Ethanol Gastroenterology Alcoholic hepatitis Endocrinology Chemistry Biochemistry Disease Alcohol Oxidoreductases analysis Alcohol Oxidoreductases analysis Alcohol Oxidoreductases analysis Alcohol Oxidoreductases metabolism Alcohol Oxidoreductases metabolism Alcohol Oxidoreductases metabolism Alcoholism metabolism Alcoholism metabolism Alcoholism metabolism Biopsy Biopsy Biopsy Fatty Liver metabolism Fatty Liver metabolism Fatty Liver metabolism Humans Humans Humans Liver enzymology Liver enzymology Liver enzymology Liver Cirrhosis metabolism Liver Cirrhosis metabolism Liver Cirrhosis metabolism Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment Health Sciences Medicine Endocrinology, Diabetes and Metabolism Diet, Metabolism, and Disease G Ugarte María Eugenia Pino I Insunza Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| title | Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| title_full | Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| title_fullStr | Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| title_full_unstemmed | Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| title_short | Hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| title_sort | hepatic alcohol dehydrogenase in alcoholic addicts with and without hepatic damage |
| topic | Alcohol dehydrogenase Steatosis Alcoholic liver disease Internal medicine Alcoholic fatty liver Fatty liver Cirrhosis Alcohol Medicine Ethanol Gastroenterology Alcoholic hepatitis Endocrinology Chemistry Biochemistry Disease Alcohol dehydrogenase Steatosis Alcoholic liver disease Internal medicine Alcoholic fatty liver Fatty liver Cirrhosis Alcohol Medicine Ethanol Gastroenterology Alcoholic hepatitis Endocrinology Chemistry Biochemistry Disease Alcohol Oxidoreductases analysis Alcohol Oxidoreductases analysis Alcohol Oxidoreductases analysis Alcohol Oxidoreductases metabolism Alcohol Oxidoreductases metabolism Alcohol Oxidoreductases metabolism Alcoholism metabolism Alcoholism metabolism Alcoholism metabolism Biopsy Biopsy Biopsy Fatty Liver metabolism Fatty Liver metabolism Fatty Liver metabolism Humans Humans Humans Liver enzymology Liver enzymology Liver enzymology Liver Cirrhosis metabolism Liver Cirrhosis metabolism Liver Cirrhosis metabolism Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment Health Sciences Medicine Endocrinology, Diabetes and Metabolism Diet, Metabolism, and Disease |
| topic_facet | Alcohol dehydrogenase Steatosis Alcoholic liver disease Internal medicine Alcoholic fatty liver Fatty liver Cirrhosis Alcohol Medicine Ethanol Gastroenterology Alcoholic hepatitis Endocrinology Chemistry Biochemistry Disease Alcohol dehydrogenase Steatosis Alcoholic liver disease Internal medicine Alcoholic fatty liver Fatty liver Cirrhosis Alcohol Medicine Ethanol Gastroenterology Alcoholic hepatitis Endocrinology Chemistry Biochemistry Disease Alcohol Oxidoreductases analysis Alcohol Oxidoreductases analysis Alcohol Oxidoreductases analysis Alcohol Oxidoreductases metabolism Alcohol Oxidoreductases metabolism Alcohol Oxidoreductases metabolism Alcoholism metabolism Alcoholism metabolism Alcoholism metabolism Biopsy Biopsy Biopsy Fatty Liver metabolism Fatty Liver metabolism Fatty Liver metabolism Humans Humans Humans Liver enzymology Liver enzymology Liver enzymology Liver Cirrhosis metabolism Liver Cirrhosis metabolism Liver Cirrhosis metabolism Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment Health Sciences Medicine Endocrinology, Diabetes and Metabolism Diet, Metabolism, and Disease |
| url | https://pubmed.ncbi.nlm.nih.gov/6027589 https://hdl.handle.net/20.500.15037/1711 |
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