Effects of Ethanol on Hepatic Blood Flow in the Rat
Hepatic blood flow measured by indocyanine green clearance was studied in rats after an acute intoxicating dose of ethanol (2 g/kg) or after chronic ethanol administration by feeding with alcohol liquid diets. Acute intoxication to normal animals did not modify hepatic blood flow. In chronically alc...
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| Formato: | Artículo |
| Lenguaje: | inglés |
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1981
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| _version_ | 1881508821849866240 |
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| author | H Iturriaga Daniel Bunout Margarita Petermanri G Ugarte Yedi Israel |
| author_browse | Daniel Bunout G Ugarte H Iturriaga Margarita Petermanri Yedi Israel |
| author_facet | H Iturriaga Daniel Bunout Margarita Petermanri G Ugarte Yedi Israel |
| author_sort | H Iturriaga |
| collection | Producción científica |
| description | Hepatic blood flow measured by indocyanine green clearance was studied in rats after an acute intoxicating dose of ethanol (2 g/kg) or after chronic ethanol administration by feeding with alcohol liquid diets. Acute intoxication to normal animals did not modify hepatic blood flow. In chronically alcohol-fed rats, hepatic blood flow was significantly decreased when measured after 15 hr of abstinence. If ethanol was not withdrawn and an acute dose of ethanol was given before the indocyanine green clearance, a decreased hepatic blood flow was not observed. It is suggested that the reduction of hepatic blood flow in recently abstinent chronically alcohol-treated animals is related to the withdrawal syndrome. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/1677 |
| institution | UPeU |
| language | English |
| publishDate | 1981 |
| publishDateRange | 1981 |
| publishDateSort | 1981 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/16772026-10-30T16:16:27ZEffects of Ethanol on Hepatic Blood Flow in the RatH IturriagaDaniel BunoutMargarita PetermanriG UgarteYedi IsraelEthanolIndocyanine greenBlood flowAbstinenceAlcoholEndocrinologyInternal medicineMedicineChemistryAnesthesiaPathologyBiochemistryPsychiatryEthanolIndocyanine greenBlood flowAbstinenceAlcoholEndocrinologyInternal medicineMedicineChemistryAnesthesiaPathologyBiochemistryEthanol pharmacologyEthanol pharmacologyEthanol pharmacologyAlcoholic Intoxication physiopathologyAlcoholic Intoxication physiopathologyAlcoholic Intoxication physiopathologyAnimalsAnimalsAnimalsBody Weight drug effectsBody Weight drug effectsBody Weight drug effectsDietDietDietHumansHumansHumansLiver Circulation drug effectsLiver Circulation drug effectsLiver Circulation drug effectsMaleMaleMaleSubstance Withdrawal Syndrome physiopathologySubstance Withdrawal Syndrome physiopathologySubstance Withdrawal Syndrome physiopathologyRatsRatsRatsHealth Sciences Medicine Epidemiology Liver Disease Diagnosis and TreatmentHealth Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health EffectsHealth Sciences Medicine Physiology Diet and metabolism studiesHepatic blood flow measured by indocyanine green clearance was studied in rats after an acute intoxicating dose of ethanol (2 g/kg) or after chronic ethanol administration by feeding with alcohol liquid diets. Acute intoxication to normal animals did not modify hepatic blood flow. In chronically alcohol-fed rats, hepatic blood flow was significantly decreased when measured after 15 hr of abstinence. If ethanol was not withdrawn and an acute dose of ethanol was given before the indocyanine green clearance, a decreased hepatic blood flow was not observed. It is suggested that the reduction of hepatic blood flow in recently abstinent chronically alcohol-treated animals is related to the withdrawal syndrome.Articlehttps://pubmed.ncbi.nlm.nih.gov/7018301https://repositorio.uchile.cl/handle/2250/16041510.1111/j.1530-0277.1981.tb04892.xhttps://hdl.handle.net/20.500.15037/1677W2152387170enAlcoholism Clinical and Experimental Research0145-60081530-02771981-03-012026-06-13T14:18:32Z2026-06-13T14:18:32Z |
| spellingShingle | Ethanol Indocyanine green Blood flow Abstinence Alcohol Endocrinology Internal medicine Medicine Chemistry Anesthesia Pathology Biochemistry Psychiatry Ethanol Indocyanine green Blood flow Abstinence Alcohol Endocrinology Internal medicine Medicine Chemistry Anesthesia Pathology Biochemistry Ethanol pharmacology Ethanol pharmacology Ethanol pharmacology Alcoholic Intoxication physiopathology Alcoholic Intoxication physiopathology Alcoholic Intoxication physiopathology Animals Animals Animals Body Weight drug effects Body Weight drug effects Body Weight drug effects Diet Diet Diet Humans Humans Humans Liver Circulation drug effects Liver Circulation drug effects Liver Circulation drug effects Male Male Male Substance Withdrawal Syndrome physiopathology Substance Withdrawal Syndrome physiopathology Substance Withdrawal Syndrome physiopathology Rats Rats Rats Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Health Sciences Medicine Physiology Diet and metabolism studies H Iturriaga Daniel Bunout Margarita Petermanri G Ugarte Yedi Israel Effects of Ethanol on Hepatic Blood Flow in the Rat |
| title | Effects of Ethanol on Hepatic Blood Flow in the Rat |
| title_full | Effects of Ethanol on Hepatic Blood Flow in the Rat |
| title_fullStr | Effects of Ethanol on Hepatic Blood Flow in the Rat |
| title_full_unstemmed | Effects of Ethanol on Hepatic Blood Flow in the Rat |
| title_short | Effects of Ethanol on Hepatic Blood Flow in the Rat |
| title_sort | effects of ethanol on hepatic blood flow in the rat |
| topic | Ethanol Indocyanine green Blood flow Abstinence Alcohol Endocrinology Internal medicine Medicine Chemistry Anesthesia Pathology Biochemistry Psychiatry Ethanol Indocyanine green Blood flow Abstinence Alcohol Endocrinology Internal medicine Medicine Chemistry Anesthesia Pathology Biochemistry Ethanol pharmacology Ethanol pharmacology Ethanol pharmacology Alcoholic Intoxication physiopathology Alcoholic Intoxication physiopathology Alcoholic Intoxication physiopathology Animals Animals Animals Body Weight drug effects Body Weight drug effects Body Weight drug effects Diet Diet Diet Humans Humans Humans Liver Circulation drug effects Liver Circulation drug effects Liver Circulation drug effects Male Male Male Substance Withdrawal Syndrome physiopathology Substance Withdrawal Syndrome physiopathology Substance Withdrawal Syndrome physiopathology Rats Rats Rats Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Health Sciences Medicine Physiology Diet and metabolism studies |
| topic_facet | Ethanol Indocyanine green Blood flow Abstinence Alcohol Endocrinology Internal medicine Medicine Chemistry Anesthesia Pathology Biochemistry Psychiatry Ethanol Indocyanine green Blood flow Abstinence Alcohol Endocrinology Internal medicine Medicine Chemistry Anesthesia Pathology Biochemistry Ethanol pharmacology Ethanol pharmacology Ethanol pharmacology Alcoholic Intoxication physiopathology Alcoholic Intoxication physiopathology Alcoholic Intoxication physiopathology Animals Animals Animals Body Weight drug effects Body Weight drug effects Body Weight drug effects Diet Diet Diet Humans Humans Humans Liver Circulation drug effects Liver Circulation drug effects Liver Circulation drug effects Male Male Male Substance Withdrawal Syndrome physiopathology Substance Withdrawal Syndrome physiopathology Substance Withdrawal Syndrome physiopathology Rats Rats Rats Health Sciences Medicine Epidemiology Liver Disease Diagnosis and Treatment Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Health Sciences Medicine Physiology Diet and metabolism studies |
| url | https://pubmed.ncbi.nlm.nih.gov/7018301 https://repositorio.uchile.cl/handle/2250/160415 https://hdl.handle.net/20.500.15037/1677 |
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