Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis
A clinical, serological, parasitological and therapeutic study of cutaneous leishmaniasis was carried out in a low sub-andean area (250-800 metres) of the La Paz Department, Bolivia. A team of seismic prospectors (350 workers) was surveyed for 12 months. Of 200 suspected cases of cutaneous leishmani...
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1987
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| author | P. Desjeux S. Mollinedo François Le Pont Andres Paredes G Ugarte |
| author_browse | Andres Paredes François Le Pont G Ugarte P. Desjeux S. Mollinedo |
| author_facet | P. Desjeux S. Mollinedo François Le Pont Andres Paredes G Ugarte |
| author_sort | P. Desjeux |
| collection | Producción científica |
| description | A clinical, serological, parasitological and therapeutic study of cutaneous leishmaniasis was carried out in a low sub-andean area (250-800 metres) of the La Paz Department, Bolivia. A team of seismic prospectors (350 workers) was surveyed for 12 months. Of 200 suspected cases of cutaneous leishmaniasis, 185 were serologically or parasitologically confirmed (incidence 52.8%). Those exposed to the greatest risk of infection were working in a virgin forest environment. Leishmanial organisms were isolated from 26 of the workers, either by in vitro cultivation or inoculation into hamsters. Isoenzyme characterization of the organisms by cellulose acetate electrophoresis showed them to be Leishmania braziliensis braziliensis [corrected]. The results of treatment of 168 patients with a pentavalent antimonial drug are also reported. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/1668 |
| institution | UPeU |
| language | English |
| publishDate | 1987 |
| publishDateRange | 1987 |
| publishDateSort | 1987 |
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| spelling | oai:cris.upeu.edu.pe:20.500.15037/16682026-10-30T16:16:25ZCutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensisP. DesjeuxS. MollinedoFrançois Le PontAndres ParedesG UgarteLeishmaniasisLeishmaniaSerologyCutaneous leishmaniasisIsolation (microbiology)Leishmania majorMeglumine antimoniateBiologyVeterinary medicineMicrobiologyMedicineImmunologyParasite hostingAntibodyWorld Wide WebComputer scienceLeishmaniasisLeishmaniaSerologyCutaneous leishmaniasisIsolation (microbiology)Leishmania majorMeglumine antimoniateBiologyVeterinary medicineMicrobiologyMedicineImmunologyParasite hostingAntibodyMeglumine AntimoniateMeglumine AntimoniateMeglumine AntimoniateAnimalsAnimalsAnimalsAntiprotozoal Agents therapeutic useAntiprotozoal Agents therapeutic useAntiprotozoal Agents therapeutic useBoliviaBoliviaBoliviaCricetinaeCricetinaeCricetinaeHumansHumansHumansLeishmania isolation & purificationLeishmania isolation & purificationLeishmania isolation & purificationLeishmania braziliensis classificationLeishmania braziliensis classificationLeishmania braziliensis classificationLeishmania braziliensis isolation & purificationLeishmania braziliensis isolation & purificationLeishmania braziliensis isolation & purificationLeishmaniasis drug therapyLeishmaniasis drug therapyLeishmaniasis drug therapyLeishmaniasis epidemiologyLeishmaniasis epidemiologyLeishmaniasis epidemiologyLeishmaniasis parasitologyLeishmaniasis parasitologyLeishmaniasis parasitologyMeglumine therapeutic useMeglumine therapeutic useMeglumine therapeutic useOrganometallic Compounds therapeutic useOrganometallic Compounds therapeutic useOrganometallic Compounds therapeutic useSkin parasitologySkin parasitologySkin parasitologyHealth Sciences Medicine Public Health, Environmental and Occupational Health Research on Leishmaniasis StudiesHealth Sciences Medicine Epidemiology Trypanosoma species research and implicationsA clinical, serological, parasitological and therapeutic study of cutaneous leishmaniasis was carried out in a low sub-andean area (250-800 metres) of the La Paz Department, Bolivia. A team of seismic prospectors (350 workers) was surveyed for 12 months. Of 200 suspected cases of cutaneous leishmaniasis, 185 were serologically or parasitologically confirmed (incidence 52.8%). Those exposed to the greatest risk of infection were working in a virgin forest environment. Leishmanial organisms were isolated from 26 of the workers, either by in vitro cultivation or inoculation into hamsters. Isoenzyme characterization of the organisms by cellulose acetate electrophoresis showed them to be Leishmania braziliensis braziliensis [corrected]. The results of treatment of 168 patients with a pentavalent antimonial drug are also reported.Articlehttps://pubmed.ncbi.nlm.nih.gov/344999010.1016/0035-9203(87)90014-9https://hdl.handle.net/20.500.15037/1668W2025397453enTransactions of the Royal Society of Tropical Medicine and Hygiene0035-92031878-35031987-09-012026-06-13T14:18:17Z2026-06-13T14:18:17Z |
| spellingShingle | Leishmaniasis Leishmania Serology Cutaneous leishmaniasis Isolation (microbiology) Leishmania major Meglumine antimoniate Biology Veterinary medicine Microbiology Medicine Immunology Parasite hosting Antibody World Wide Web Computer science Leishmaniasis Leishmania Serology Cutaneous leishmaniasis Isolation (microbiology) Leishmania major Meglumine antimoniate Biology Veterinary medicine Microbiology Medicine Immunology Parasite hosting Antibody Meglumine Antimoniate Meglumine Antimoniate Meglumine Antimoniate Animals Animals Animals Antiprotozoal Agents therapeutic use Antiprotozoal Agents therapeutic use Antiprotozoal Agents therapeutic use Bolivia Bolivia Bolivia Cricetinae Cricetinae Cricetinae Humans Humans Humans Leishmania isolation & purification Leishmania isolation & purification Leishmania isolation & purification Leishmania braziliensis classification Leishmania braziliensis classification Leishmania braziliensis classification Leishmania braziliensis isolation & purification Leishmania braziliensis isolation & purification Leishmania braziliensis isolation & purification Leishmaniasis drug therapy Leishmaniasis drug therapy Leishmaniasis drug therapy Leishmaniasis epidemiology Leishmaniasis epidemiology Leishmaniasis epidemiology Leishmaniasis parasitology Leishmaniasis parasitology Leishmaniasis parasitology Meglumine therapeutic use Meglumine therapeutic use Meglumine therapeutic use Organometallic Compounds therapeutic use Organometallic Compounds therapeutic use Organometallic Compounds therapeutic use Skin parasitology Skin parasitology Skin parasitology Health Sciences Medicine Public Health, Environmental and Occupational Health Research on Leishmaniasis Studies Health Sciences Medicine Epidemiology Trypanosoma species research and implications P. Desjeux S. Mollinedo François Le Pont Andres Paredes G Ugarte Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis |
| title | Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis |
| title_full | Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis |
| title_fullStr | Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis |
| title_full_unstemmed | Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis |
| title_short | Cutaneous leishmaniasis in Bolivia. A study of 185 human cases from Alto Beni (La Paz Department). Isolation and isoenzyme characterization of 26 strains of Leishmania brasiliensis brasiliensis |
| title_sort | cutaneous leishmaniasis in bolivia a study of 185 human cases from alto beni la paz department isolation and isoenzyme characterization of 26 strains of leishmania brasiliensis brasiliensis |
| topic | Leishmaniasis Leishmania Serology Cutaneous leishmaniasis Isolation (microbiology) Leishmania major Meglumine antimoniate Biology Veterinary medicine Microbiology Medicine Immunology Parasite hosting Antibody World Wide Web Computer science Leishmaniasis Leishmania Serology Cutaneous leishmaniasis Isolation (microbiology) Leishmania major Meglumine antimoniate Biology Veterinary medicine Microbiology Medicine Immunology Parasite hosting Antibody Meglumine Antimoniate Meglumine Antimoniate Meglumine Antimoniate Animals Animals Animals Antiprotozoal Agents therapeutic use Antiprotozoal Agents therapeutic use Antiprotozoal Agents therapeutic use Bolivia Bolivia Bolivia Cricetinae Cricetinae Cricetinae Humans Humans Humans Leishmania isolation & purification Leishmania isolation & purification Leishmania isolation & purification Leishmania braziliensis classification Leishmania braziliensis classification Leishmania braziliensis classification Leishmania braziliensis isolation & purification Leishmania braziliensis isolation & purification Leishmania braziliensis isolation & purification Leishmaniasis drug therapy Leishmaniasis drug therapy Leishmaniasis drug therapy Leishmaniasis epidemiology Leishmaniasis epidemiology Leishmaniasis epidemiology Leishmaniasis parasitology Leishmaniasis parasitology Leishmaniasis parasitology Meglumine therapeutic use Meglumine therapeutic use Meglumine therapeutic use Organometallic Compounds therapeutic use Organometallic Compounds therapeutic use Organometallic Compounds therapeutic use Skin parasitology Skin parasitology Skin parasitology Health Sciences Medicine Public Health, Environmental and Occupational Health Research on Leishmaniasis Studies Health Sciences Medicine Epidemiology Trypanosoma species research and implications |
| topic_facet | Leishmaniasis Leishmania Serology Cutaneous leishmaniasis Isolation (microbiology) Leishmania major Meglumine antimoniate Biology Veterinary medicine Microbiology Medicine Immunology Parasite hosting Antibody World Wide Web Computer science Leishmaniasis Leishmania Serology Cutaneous leishmaniasis Isolation (microbiology) Leishmania major Meglumine antimoniate Biology Veterinary medicine Microbiology Medicine Immunology Parasite hosting Antibody Meglumine Antimoniate Meglumine Antimoniate Meglumine Antimoniate Animals Animals Animals Antiprotozoal Agents therapeutic use Antiprotozoal Agents therapeutic use Antiprotozoal Agents therapeutic use Bolivia Bolivia Bolivia Cricetinae Cricetinae Cricetinae Humans Humans Humans Leishmania isolation & purification Leishmania isolation & purification Leishmania isolation & purification Leishmania braziliensis classification Leishmania braziliensis classification Leishmania braziliensis classification Leishmania braziliensis isolation & purification Leishmania braziliensis isolation & purification Leishmania braziliensis isolation & purification Leishmaniasis drug therapy Leishmaniasis drug therapy Leishmaniasis drug therapy Leishmaniasis epidemiology Leishmaniasis epidemiology Leishmaniasis epidemiology Leishmaniasis parasitology Leishmaniasis parasitology Leishmaniasis parasitology Meglumine therapeutic use Meglumine therapeutic use Meglumine therapeutic use Organometallic Compounds therapeutic use Organometallic Compounds therapeutic use Organometallic Compounds therapeutic use Skin parasitology Skin parasitology Skin parasitology Health Sciences Medicine Public Health, Environmental and Occupational Health Research on Leishmaniasis Studies Health Sciences Medicine Epidemiology Trypanosoma species research and implications |
| url | https://pubmed.ncbi.nlm.nih.gov/3449990 https://hdl.handle.net/20.500.15037/1668 |
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