Changes in Microsomal Activity in Alcoholism and Obesity

BACKGROUND: Liver damage is more prevalent among obese alcoholics, and cytochrome P-4502E1(CYP2E1) induction is involved in its pathogenesis. OBJECTIVES: The study was undertaken to assess microsomal function, in alcoholic and nonalcoholic male subjects with different body compositions, through phar...

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Autores principales:	M. P a de la Maza, Sandra Hirsch, Margarita Petermann, Myriam Suazo, G Ugarte, Daniel Bunout
Formato:	Artículo
Lenguaje:	inglés
Publicado:	2000
Materias:	Internal medicine Medicine Endocrinology Obesity Analysis of variance Gastroenterology Adult Alcoholism enzymology Analysis of Variance Chlorzoxazone blood Chlorzoxazone pharmacokinetics Humans Liver Cirrhosis, Alcoholic metabolism Male Microsomes, Liver metabolism Middle Aged Muscle Relaxants, Central blood Muscle Relaxants, Central pharmacokinetics Obesity enzymology Cytochrome P-450 CYP2E1 metabolism Health Sciences Medicine Pathology and Forensic Medicine Alcohol Consumption and Health Effects Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research Carcinogens and Genotoxicity Assessment Life Sciences Pharmacology, Toxicology and Pharmaceutics Toxicology Forensic Toxicology and Drug Analysis
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Changes in Microsomal Activity in Alcoholism and Obesity

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