Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review
Hepatitis C virus still represents a major cause of morbidity and mortality worldwide. In Peru, two national practice guidelines for the management of this infection were published more than 5 years ago; however, the latest breakthroughs in the treatment make it necessary to update these guidelines....
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| Formato: | Artículo de revisión |
| Lenguaje: | inglés |
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2024
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| _version_ | 1881508958224515072 |
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| author | Gonzales-Zamora, Jose A. Quispe‐Vicuña, Carlos Reategui-Garcia, Martín E. Araoz-Salinas, Julieta M. Ccami‐Bernal, Fabricio Morocho-Alburqueque, Noelia Espinoza-Herreros, Jian Pierre Layme, Josue Aquino-Sandoval, Gabriel Campos, Victor Y. Melt Alave Rosas, Jorge Luis |
| author_browse | Alave Rosas, Jorge Luis Aquino-Sandoval, Gabriel Araoz-Salinas, Julieta M. Campos, Victor Y. Melt Ccami‐Bernal, Fabricio Espinoza-Herreros, Jian Pierre Gonzales-Zamora, Jose A. Layme, Josue Morocho-Alburqueque, Noelia Quispe‐Vicuña, Carlos Reategui-Garcia, Martín E. |
| author_facet | Gonzales-Zamora, Jose A. Quispe‐Vicuña, Carlos Reategui-Garcia, Martín E. Araoz-Salinas, Julieta M. Ccami‐Bernal, Fabricio Morocho-Alburqueque, Noelia Espinoza-Herreros, Jian Pierre Layme, Josue Aquino-Sandoval, Gabriel Campos, Victor Y. Melt Alave Rosas, Jorge Luis |
| author_sort | Gonzales-Zamora, Jose A. |
| collection | Producción científica |
| description | Hepatitis C virus still represents a major cause of morbidity and mortality worldwide. In Peru, two national practice guidelines for the management of this infection were published more than 5 years ago; however, the latest breakthroughs in the treatment make it necessary to update these guidelines. We reviewed the most recent recommendations of the international guidelines and compared them with the current Peruvian guidelines. We found major differences, such as the use of Glecaprevir/Pibrentasvir as a first-line therapy, which is contemplated in the World Health Organization guideline, and recommended by American and European guidelines, but is not considered in the Peruvian guidelines. Another crucial difference lies in the management of patients with chronic kidney disease, who are treated nowadays with a variety of direct-acting antivirals, with no restrictions on the use of Sofosbuvir-based regimens in first-world countries, an approach that has not been adopted in Peru. We believe that standardization of the recommendations of the Peruvian guidelines is imperative, including the new therapeutic strategies that have emerged in recent years. We also suggest conducting a cost effectiveness analysis in the Peruvian context to allow for the implementation of new antivirals, and to achieve a better control of hepatitis C in the country. |
| format | Review |
| id | oai:cris.upeu.edu.pe:20.500.15037/154 |
| institution | UPeU |
| language | English |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/1542026-11-02T12:57:04ZIdentifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative ReviewGonzales-Zamora, Jose A.Quispe‐Vicuña, CarlosReategui-Garcia, Martín E.Araoz-Salinas, Julieta M.Ccami‐Bernal, FabricioMorocho-Alburqueque, NoeliaEspinoza-Herreros, Jian PierreLayme, JosueAquino-Sandoval, GabrielCampos, Victor Y. MeltAlave Rosas, Jorge LuisCirrhosisTreatmentRenal diseasehepatitis CRecommendationsPeruHepatitis C virus still represents a major cause of morbidity and mortality worldwide. In Peru, two national practice guidelines for the management of this infection were published more than 5 years ago; however, the latest breakthroughs in the treatment make it necessary to update these guidelines. We reviewed the most recent recommendations of the international guidelines and compared them with the current Peruvian guidelines. We found major differences, such as the use of Glecaprevir/Pibrentasvir as a first-line therapy, which is contemplated in the World Health Organization guideline, and recommended by American and European guidelines, but is not considered in the Peruvian guidelines. Another crucial difference lies in the management of patients with chronic kidney disease, who are treated nowadays with a variety of direct-acting antivirals, with no restrictions on the use of Sofosbuvir-based regimens in first-world countries, an approach that has not been adopted in Peru. We believe that standardization of the recommendations of the Peruvian guidelines is imperative, including the new therapeutic strategies that have emerged in recent years. We also suggest conducting a cost effectiveness analysis in the Peruvian context to allow for the implementation of new antivirals, and to achieve a better control of hepatitis C in the country.Reviewhttps://pubmed.ncbi.nlm.nih.gov/38999433https://www.mdpi.com/2077-0383/13/13/3867/pdf?version=1719745584https://doi.org/10.3390/jcm13133867PMC1124255110.3390/jcm13133867https://hdl.handle.net/20.500.15037/15438999433W4400197632enJournal of Clinical Medicine2077-03832024-06-302026-06-13T07:48:28Z2026-06-13T07:48:28Z |
| spellingShingle | Cirrhosis Treatment Renal disease hepatitis C Recommendations Peru Gonzales-Zamora, Jose A. Quispe‐Vicuña, Carlos Reategui-Garcia, Martín E. Araoz-Salinas, Julieta M. Ccami‐Bernal, Fabricio Morocho-Alburqueque, Noelia Espinoza-Herreros, Jian Pierre Layme, Josue Aquino-Sandoval, Gabriel Campos, Victor Y. Melt Alave Rosas, Jorge Luis Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review |
| title | Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review |
| title_full | Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review |
| title_fullStr | Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review |
| title_full_unstemmed | Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review |
| title_short | Identifying Gaps in the Treatment Guidelines for Hepatitis C in Peru to Meet International Standards: A Narrative Review |
| title_sort | identifying gaps in the treatment guidelines for hepatitis c in peru to meet international standards a narrative review |
| topic | Cirrhosis Treatment Renal disease hepatitis C Recommendations Peru |
| topic_facet | Cirrhosis Treatment Renal disease hepatitis C Recommendations Peru |
| url | https://pubmed.ncbi.nlm.nih.gov/38999433 https://www.mdpi.com/2077-0383/13/13/3867/pdf?version=1719745584 https://doi.org/10.3390/jcm13133867 https://hdl.handle.net/20.500.15037/154 |
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