Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate

BACKGROUND: Few studies have been published reporting risk factors for flap necrosis after primary palatoplasty in patients with cleft palate. This complication is rare, and the event is a disaster for both the patient and the surgeon. This study was performed to explore the associations between dif...

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Autores principales: Percy Rossell‐Perry, Olga Figallo-Hudtwalcker, Roberto Vargas-Chanduvi, Yvette Calderon-Ayvar, Carolina Romero-Narváez
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Publicado: 2017
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author Percy Rossell‐Perry
Olga Figallo-Hudtwalcker
Roberto Vargas-Chanduvi
Yvette Calderon-Ayvar
Carolina Romero-Narváez
author_browse Carolina Romero-Narváez
Olga Figallo-Hudtwalcker
Percy Rossell‐Perry
Roberto Vargas-Chanduvi
Yvette Calderon-Ayvar
author_facet Percy Rossell‐Perry
Olga Figallo-Hudtwalcker
Roberto Vargas-Chanduvi
Yvette Calderon-Ayvar
Carolina Romero-Narváez
author_sort Percy Rossell‐Perry
collection Producción científica
description BACKGROUND: Few studies have been published reporting risk factors for flap necrosis after primary palatoplasty in patients with cleft palate. This complication is rare, and the event is a disaster for both the patient and the surgeon. This study was performed to explore the associations between different risk factors and the development of flap necrosis after primary palatoplasty in patients with cleft palate. METHODS: This is a case-control study. A 20 years retrospective analysis (1994-2015) of patients with nonsyndromic cleft palate was identified from medical records and screening day registries). Demographical and risk factor data were collected using a patient´s report, including information about age at surgery, gender, cleft palate type, and degree of severity. Odds ratios and 95% confident intervals were derived from logistic regression analysis. RESULTS: All cases with diagnoses of flap necrosis after primary palatoplasty were included in the study (48 patients) and 156 controls were considered. In multivariate analysis, female sex, age (older than 15 years), cleft type (bilateral and incomplete), and severe cleft palate index were associated with significantly increased risk for flap necrosis. CONCLUSIONS: The findings suggest that female sex, older age, cleft type (bilateral and incomplete), and severe cleft palatal index may be associated with the development of flap necrosis after primary palatoplasty in patients with cleft palate.
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spelling oai:cris.upeu.edu.pe:20.500.15037/13242026-10-30T16:15:34ZRisk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palatePercy Rossell‐PerryOlga Figallo-HudtwalckerRoberto Vargas-ChanduviYvette Calderon-AyvarCarolina Romero-NarváezPalatoplastyMedicineOdds ratioLogistic regressionDentistryRetrospective cohort studyComplicationMedical recordSurgeryRisk factorInternal medicinePalatoplastyMedicineOdds ratioLogistic regressionDentistryRetrospective cohort studyComplicationMedical recordSurgeryRisk factorInternal medicineAdolescentAdolescentAdolescentAge FactorsAge FactorsAge FactorsChildChildChildChild, PreschoolChild, PreschoolChild, PreschoolCleft Palate diagnosisCleft Palate diagnosisCleft Palate diagnosisCleft Palate surgeryCleft Palate surgeryCleft Palate surgeryFemaleFemaleFemaleFollow-Up StudiesFollow-Up StudiesFollow-Up StudiesGraft Rejection epidemiologyGraft Rejection epidemiologyGraft Rejection epidemiologyGraft Rejection pathologyGraft Rejection pathologyGraft Rejection pathologyHumansHumansHumansInfantInfantInfantMaleMaleMaleMouth Mucosa transplantationMouth Mucosa transplantationMouth Mucosa transplantationNecrosis pathologyNecrosis pathologyNecrosis pathologyPeriosteum blood supplyPeriosteum blood supplyPeriosteum blood supplyPeriosteum transplantationPeriosteum transplantationPeriosteum transplantationRetrospective StudiesRetrospective StudiesRetrospective StudiesRisk FactorsRisk FactorsRisk FactorsSex FactorsSex FactorsSex FactorsSurgical Flaps pathologySurgical Flaps pathologySurgical Flaps pathologySurgical Flaps transplantationSurgical Flaps transplantationSurgical Flaps transplantationTaiwanTaiwanTaiwanMultivariate AnalysisMultivariate AnalysisMultivariate AnalysisLogistic ModelsLogistic ModelsLogistic ModelsCase-Control StudiesCase-Control StudiesCase-Control StudiesTreatment OutcomeTreatment OutcomeTreatment OutcomeStatistics, NonparametricStatistics, NonparametricStatistics, NonparametricPlastic Surgery Procedures adverse effectsPlastic Surgery Procedures adverse effectsPlastic Surgery Procedures adverse effectsPlastic Surgery Procedures methodsPlastic Surgery Procedures methodsPlastic Surgery Procedures methodsLife Sciences Biochemistry, Genetics and Molecular Biology Genetics Cleft Lip and Palate ResearchHealth Sciences Medicine Surgery Reconstructive Surgery and Microvascular TechniquesHealth Sciences Medicine Public Health, Environmental and Occupational Health HIV/AIDS oral health manifestationsBACKGROUND: Few studies have been published reporting risk factors for flap necrosis after primary palatoplasty in patients with cleft palate. This complication is rare, and the event is a disaster for both the patient and the surgeon. This study was performed to explore the associations between different risk factors and the development of flap necrosis after primary palatoplasty in patients with cleft palate. METHODS: This is a case-control study. A 20 years retrospective analysis (1994-2015) of patients with nonsyndromic cleft palate was identified from medical records and screening day registries). Demographical and risk factor data were collected using a patient´s report, including information about age at surgery, gender, cleft palate type, and degree of severity. Odds ratios and 95% confident intervals were derived from logistic regression analysis. RESULTS: All cases with diagnoses of flap necrosis after primary palatoplasty were included in the study (48 patients) and 156 controls were considered. In multivariate analysis, female sex, age (older than 15 years), cleft type (bilateral and incomplete), and severe cleft palate index were associated with significantly increased risk for flap necrosis. CONCLUSIONS: The findings suggest that female sex, older age, cleft type (bilateral and incomplete), and severe cleft palatal index may be associated with the development of flap necrosis after primary palatoplasty in patients with cleft palate.Articlehttps://pubmed.ncbi.nlm.nih.gov/28084113https://doi.org/10.1080/2000656x.2016.127021610.1080/2000656x.2016.1270216https://hdl.handle.net/20.500.15037/1324W2571706521enJournal of Plastic Surgery and Hand Surgery2000-656X2000-67642017-01-132026-06-13T09:53:23Z2026-06-13T09:53:23Z
spellingShingle Palatoplasty
Medicine
Odds ratio
Logistic regression
Dentistry
Retrospective cohort study
Complication
Medical record
Surgery
Risk factor
Internal medicine
Palatoplasty
Medicine
Odds ratio
Logistic regression
Dentistry
Retrospective cohort study
Complication
Medical record
Surgery
Risk factor
Internal medicine
Adolescent
Adolescent
Adolescent
Age Factors
Age Factors
Age Factors
Child
Child
Child
Child, Preschool
Child, Preschool
Child, Preschool
Cleft Palate diagnosis
Cleft Palate diagnosis
Cleft Palate diagnosis
Cleft Palate surgery
Cleft Palate surgery
Cleft Palate surgery
Female
Female
Female
Follow-Up Studies
Follow-Up Studies
Follow-Up Studies
Graft Rejection epidemiology
Graft Rejection epidemiology
Graft Rejection epidemiology
Graft Rejection pathology
Graft Rejection pathology
Graft Rejection pathology
Humans
Humans
Humans
Infant
Infant
Infant
Male
Male
Male
Mouth Mucosa transplantation
Mouth Mucosa transplantation
Mouth Mucosa transplantation
Necrosis pathology
Necrosis pathology
Necrosis pathology
Periosteum blood supply
Periosteum blood supply
Periosteum blood supply
Periosteum transplantation
Periosteum transplantation
Periosteum transplantation
Retrospective Studies
Retrospective Studies
Retrospective Studies
Risk Factors
Risk Factors
Risk Factors
Sex Factors
Sex Factors
Sex Factors
Surgical Flaps pathology
Surgical Flaps pathology
Surgical Flaps pathology
Surgical Flaps transplantation
Surgical Flaps transplantation
Surgical Flaps transplantation
Taiwan
Taiwan
Taiwan
Multivariate Analysis
Multivariate Analysis
Multivariate Analysis
Logistic Models
Logistic Models
Logistic Models
Case-Control Studies
Case-Control Studies
Case-Control Studies
Treatment Outcome
Treatment Outcome
Treatment Outcome
Statistics, Nonparametric
Statistics, Nonparametric
Statistics, Nonparametric
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures methods
Plastic Surgery Procedures methods
Plastic Surgery Procedures methods
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics Cleft Lip and Palate Research
Health Sciences Medicine Surgery Reconstructive Surgery and Microvascular Techniques
Health Sciences Medicine Public Health, Environmental and Occupational Health HIV/AIDS oral health manifestations
Percy Rossell‐Perry
Olga Figallo-Hudtwalcker
Roberto Vargas-Chanduvi
Yvette Calderon-Ayvar
Carolina Romero-Narváez
Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
title Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
title_full Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
title_fullStr Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
title_full_unstemmed Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
title_short Risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
title_sort risk factors leading to mucoperiosteal flap necrosis after primary palatoplasty in patents with cleft palate
topic Palatoplasty
Medicine
Odds ratio
Logistic regression
Dentistry
Retrospective cohort study
Complication
Medical record
Surgery
Risk factor
Internal medicine
Palatoplasty
Medicine
Odds ratio
Logistic regression
Dentistry
Retrospective cohort study
Complication
Medical record
Surgery
Risk factor
Internal medicine
Adolescent
Adolescent
Adolescent
Age Factors
Age Factors
Age Factors
Child
Child
Child
Child, Preschool
Child, Preschool
Child, Preschool
Cleft Palate diagnosis
Cleft Palate diagnosis
Cleft Palate diagnosis
Cleft Palate surgery
Cleft Palate surgery
Cleft Palate surgery
Female
Female
Female
Follow-Up Studies
Follow-Up Studies
Follow-Up Studies
Graft Rejection epidemiology
Graft Rejection epidemiology
Graft Rejection epidemiology
Graft Rejection pathology
Graft Rejection pathology
Graft Rejection pathology
Humans
Humans
Humans
Infant
Infant
Infant
Male
Male
Male
Mouth Mucosa transplantation
Mouth Mucosa transplantation
Mouth Mucosa transplantation
Necrosis pathology
Necrosis pathology
Necrosis pathology
Periosteum blood supply
Periosteum blood supply
Periosteum blood supply
Periosteum transplantation
Periosteum transplantation
Periosteum transplantation
Retrospective Studies
Retrospective Studies
Retrospective Studies
Risk Factors
Risk Factors
Risk Factors
Sex Factors
Sex Factors
Sex Factors
Surgical Flaps pathology
Surgical Flaps pathology
Surgical Flaps pathology
Surgical Flaps transplantation
Surgical Flaps transplantation
Surgical Flaps transplantation
Taiwan
Taiwan
Taiwan
Multivariate Analysis
Multivariate Analysis
Multivariate Analysis
Logistic Models
Logistic Models
Logistic Models
Case-Control Studies
Case-Control Studies
Case-Control Studies
Treatment Outcome
Treatment Outcome
Treatment Outcome
Statistics, Nonparametric
Statistics, Nonparametric
Statistics, Nonparametric
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures methods
Plastic Surgery Procedures methods
Plastic Surgery Procedures methods
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics Cleft Lip and Palate Research
Health Sciences Medicine Surgery Reconstructive Surgery and Microvascular Techniques
Health Sciences Medicine Public Health, Environmental and Occupational Health HIV/AIDS oral health manifestations
topic_facet Palatoplasty
Medicine
Odds ratio
Logistic regression
Dentistry
Retrospective cohort study
Complication
Medical record
Surgery
Risk factor
Internal medicine
Palatoplasty
Medicine
Odds ratio
Logistic regression
Dentistry
Retrospective cohort study
Complication
Medical record
Surgery
Risk factor
Internal medicine
Adolescent
Adolescent
Adolescent
Age Factors
Age Factors
Age Factors
Child
Child
Child
Child, Preschool
Child, Preschool
Child, Preschool
Cleft Palate diagnosis
Cleft Palate diagnosis
Cleft Palate diagnosis
Cleft Palate surgery
Cleft Palate surgery
Cleft Palate surgery
Female
Female
Female
Follow-Up Studies
Follow-Up Studies
Follow-Up Studies
Graft Rejection epidemiology
Graft Rejection epidemiology
Graft Rejection epidemiology
Graft Rejection pathology
Graft Rejection pathology
Graft Rejection pathology
Humans
Humans
Humans
Infant
Infant
Infant
Male
Male
Male
Mouth Mucosa transplantation
Mouth Mucosa transplantation
Mouth Mucosa transplantation
Necrosis pathology
Necrosis pathology
Necrosis pathology
Periosteum blood supply
Periosteum blood supply
Periosteum blood supply
Periosteum transplantation
Periosteum transplantation
Periosteum transplantation
Retrospective Studies
Retrospective Studies
Retrospective Studies
Risk Factors
Risk Factors
Risk Factors
Sex Factors
Sex Factors
Sex Factors
Surgical Flaps pathology
Surgical Flaps pathology
Surgical Flaps pathology
Surgical Flaps transplantation
Surgical Flaps transplantation
Surgical Flaps transplantation
Taiwan
Taiwan
Taiwan
Multivariate Analysis
Multivariate Analysis
Multivariate Analysis
Logistic Models
Logistic Models
Logistic Models
Case-Control Studies
Case-Control Studies
Case-Control Studies
Treatment Outcome
Treatment Outcome
Treatment Outcome
Statistics, Nonparametric
Statistics, Nonparametric
Statistics, Nonparametric
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures adverse effects
Plastic Surgery Procedures methods
Plastic Surgery Procedures methods
Plastic Surgery Procedures methods
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics Cleft Lip and Palate Research
Health Sciences Medicine Surgery Reconstructive Surgery and Microvascular Techniques
Health Sciences Medicine Public Health, Environmental and Occupational Health HIV/AIDS oral health manifestations
url https://pubmed.ncbi.nlm.nih.gov/28084113
https://doi.org/10.1080/2000656x.2016.1270216
https://hdl.handle.net/20.500.15037/1324
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