Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy
Importance: Data on oncological outcomes after omission of axillary lymph node dissection (ALND) in patients with breast cancer that downstages from node positive to negative with neoadjuvant chemotherapy are sparse. Additionally, the best axillary surgical staging technique in this scenario is unkn...
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| author | Giacomo Montagna Mary M. Mrdutt Susie X. Sun Callie Hlavin Emilia J. Diego Stephanie M. Wong Andrea V. Barrio Astrid Botty van den Bruele Neslihan Cabıoğlu Varadan Sevilimedu Laura H. Rosenberger E. Shelley Hwang Abigail Ingham Bärbel Papassotiropoulos Bich Doan Nguyen-Sträuli Christian Kurzeder Danilo Díaz Aybar Denise Vorburger Dieter Michael Matlac Edvin Ostapenko Fabian Riedel Florian Fitzal Francesco Meani Franziska Fick Jacqueline Sagasser Jörg Heil Hasan Karanlık Konstantin J. Dedes László Romics Maggie Banys‐Paluchowski Mahmut Müslümanoğlu María del Rosario Cueva Pérez Marcelo Chávez Díaz Martin Heidinger Mathias K. Fehr Mattea Reinisch Mustafa Tükenmez Nadia Maggi Nicola Rocco Nina Ditsch Oreste Gentilini Régis Resende Paulinelli Sebastián Solé Zarhi Sherko Küemmel S. Bruz̆as Simona Di Lascio Tamara K. Parissenti Tanya L. Hoskin Uwe Güth Valentina Ovalle Christoph Tausch Henry M. Kuerer Abigail S. Caudle Jean-François Boileau Judy C. Boughey Thorsten Kühn Monica Morrow William P. Weber |
| author_browse | Abigail Ingham Abigail S. Caudle Andrea V. Barrio Astrid Botty van den Bruele Bich Doan Nguyen-Sträuli Bärbel Papassotiropoulos Callie Hlavin Christian Kurzeder Christoph Tausch Danilo Díaz Aybar Denise Vorburger Dieter Michael Matlac E. Shelley Hwang Edvin Ostapenko Emilia J. Diego Fabian Riedel Florian Fitzal Francesco Meani Franziska Fick Giacomo Montagna Hasan Karanlık Henry M. Kuerer Jacqueline Sagasser Jean-François Boileau Judy C. Boughey Jörg Heil Konstantin J. Dedes Laura H. Rosenberger László Romics Maggie Banys‐Paluchowski Mahmut Müslümanoğlu Marcelo Chávez Díaz Martin Heidinger Mary M. Mrdutt María del Rosario Cueva Pérez Mathias K. Fehr Mattea Reinisch Monica Morrow Mustafa Tükenmez Nadia Maggi Neslihan Cabıoğlu Nicola Rocco Nina Ditsch Oreste Gentilini Régis Resende Paulinelli S. Bruz̆as Sebastián Solé Zarhi Sherko Küemmel Simona Di Lascio Stephanie M. Wong Susie X. Sun Tamara K. Parissenti Tanya L. Hoskin Thorsten Kühn Uwe Güth Valentina Ovalle Varadan Sevilimedu William P. Weber |
| author_facet | Giacomo Montagna Mary M. Mrdutt Susie X. Sun Callie Hlavin Emilia J. Diego Stephanie M. Wong Andrea V. Barrio Astrid Botty van den Bruele Neslihan Cabıoğlu Varadan Sevilimedu Laura H. Rosenberger E. Shelley Hwang Abigail Ingham Bärbel Papassotiropoulos Bich Doan Nguyen-Sträuli Christian Kurzeder Danilo Díaz Aybar Denise Vorburger Dieter Michael Matlac Edvin Ostapenko Fabian Riedel Florian Fitzal Francesco Meani Franziska Fick Jacqueline Sagasser Jörg Heil Hasan Karanlık Konstantin J. Dedes László Romics Maggie Banys‐Paluchowski Mahmut Müslümanoğlu María del Rosario Cueva Pérez Marcelo Chávez Díaz Martin Heidinger Mathias K. Fehr Mattea Reinisch Mustafa Tükenmez Nadia Maggi Nicola Rocco Nina Ditsch Oreste Gentilini Régis Resende Paulinelli Sebastián Solé Zarhi Sherko Küemmel S. Bruz̆as Simona Di Lascio Tamara K. Parissenti Tanya L. Hoskin Uwe Güth Valentina Ovalle Christoph Tausch Henry M. Kuerer Abigail S. Caudle Jean-François Boileau Judy C. Boughey Thorsten Kühn Monica Morrow William P. Weber |
| author_sort | Giacomo Montagna |
| collection | Producción científica |
| description | Importance: Data on oncological outcomes after omission of axillary lymph node dissection (ALND) in patients with breast cancer that downstages from node positive to negative with neoadjuvant chemotherapy are sparse. Additionally, the best axillary surgical staging technique in this scenario is unknown. Objective: To investigate oncological outcomes after sentinel lymph node biopsy (SLNB) with dual-tracer mapping or targeted axillary dissection (TAD), which combines SLNB with localization and retrieval of the clipped lymph node. Design, Setting, and Participants: In this multicenter retrospective cohort study that was conducted at 25 centers in 11 countries, 1144 patients with consecutive stage II to III biopsy-proven node-positive breast cancer were included between April 2013 and December 2020. The cumulative incidence rates of axillary, locoregional, and any invasive (locoregional or distant) recurrence were determined by competing risk analysis. Exposure: Omission of ALND after SLNB or TAD. Main Outcomes and Measures: The primary end points were the 3-year and 5-year rates of any axillary recurrence. Secondary end points included locoregional recurrence, any invasive (locoregional and distant) recurrence, and the number of lymph nodes removed. Results: A total of 1144 patients (median [IQR] age, 50 [41-59] years; 78 [6.8%] Asian, 105 [9.2%] Black, 102 [8.9%] Hispanic, and 816 [71.0%] White individuals; 666 SLNB [58.2%] and 478 TAD [41.8%]) were included. A total of 1060 patients (93%) had N1 disease, 619 (54%) had ERBB2 (formerly HER2)-positive illness, and 758 (66%) had a breast pathologic complete response. TAD patients were more likely to receive nodal radiation therapy (85% vs 78%; P = .01). The clipped node was successfully retrieved in 97% of TAD cases and 86% of SLNB cases (without localization). The mean (SD) number of sentinel lymph nodes retrieved was 3 (2) vs 4 (2) (P < .001), and the mean (SD) number of total lymph nodes removed was 3.95 (1.97) vs 4.44 (2.04) (P < .001) in the TAD and SLNB groups, respectively. The 5-year rates of any axillary, locoregional, and any invasive recurrence in the entire cohort were 1.0% (95% CI, 0.49%-2.0%), 2.7% (95% CI, 1.6%-4.1%), and 10% (95% CI, 8.3%-13%), respectively. The 3-year cumulative incidence of axillary recurrence did not differ between TAD and SLNB (0.5% vs 0.8%; P = .55). Conclusions and Relevance: The results of this cohort study showed that axillary recurrence was rare in this setting and was not significantly lower after TAD vs SLNB. These results support omission of ALND in this population. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/1183 |
| institution | UPeU |
| language | English |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/11832026-10-30T16:15:19ZOmission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant ChemotherapyGiacomo MontagnaMary M. MrduttSusie X. SunCallie HlavinEmilia J. DiegoStephanie M. WongAndrea V. BarrioAstrid Botty van den BrueleNeslihan CabıoğluVaradan SevilimeduLaura H. RosenbergerE. Shelley HwangAbigail InghamBärbel PapassotiropoulosBich Doan Nguyen-SträuliChristian KurzederDanilo Díaz AybarDenise VorburgerDieter Michael MatlacEdvin OstapenkoFabian RiedelFlorian FitzalFrancesco MeaniFranziska FickJacqueline SagasserJörg HeilHasan KaranlıkKonstantin J. DedesLászló RomicsMaggie Banys‐PaluchowskiMahmut MüslümanoğluMaría del Rosario Cueva PérezMarcelo Chávez DíazMartin HeidingerMathias K. FehrMattea ReinischMustafa TükenmezNadia MaggiNicola RoccoNina DitschOreste GentiliniRégis Resende PaulinelliSebastián Solé ZarhiSherko KüemmelS. Bruz̆asSimona Di LascioTamara K. ParissentiTanya L. HoskinUwe GüthValentina OvalleChristoph TauschHenry M. KuererAbigail S. CaudleJean-François BoileauJudy C. BougheyThorsten KühnMonica MorrowWilliam P. WeberMedicineAxillary Lymph Node DissectionBreast cancerSentinel lymph nodeBiopsyAxillaNeoadjuvant therapyRetrospective cohort studyStage (stratigraphy)SurgeryDissection (medical)Lymph nodeRadiologyCancerInternal medicineBiologyPaleontologyMedicineAxillary Lymph Node DissectionBreast cancerSentinel lymph nodeBiopsyAxillaNeoadjuvant therapyRetrospective cohort studyStage (stratigraphy)SurgeryDissection (medical)Lymph nodeRadiologyCancerInternal medicineAdultAdultAdultAdultAdultAdultAdultAgedAgedAgedAgedAgedAgedAgedAxillaAxillaAxillaAxillaAxillaAxillaAxillaBreast Neoplasms drug therapyBreast Neoplasms drug therapyBreast Neoplasms drug therapyBreast Neoplasms drug therapyBreast Neoplasms drug therapyBreast Neoplasms drug therapyBreast Neoplasms drug therapyBreast Neoplasms pathologyBreast Neoplasms pathologyBreast Neoplasms pathologyBreast Neoplasms pathologyBreast Neoplasms pathologyBreast Neoplasms pathologyBreast Neoplasms pathologyBreast Neoplasms surgeryBreast Neoplasms surgeryBreast Neoplasms surgeryBreast Neoplasms surgeryBreast Neoplasms surgeryBreast Neoplasms surgeryBreast Neoplasms surgeryBreast Neoplasms therapyBreast Neoplasms therapyBreast Neoplasms therapyBreast Neoplasms therapyBreast Neoplasms therapyBreast Neoplasms therapyBreast Neoplasms therapyFemaleFemaleFemaleFemaleFemaleFemaleFemaleHumansHumansHumansHumansHumansHumansHumansLymph Node ExcisionLymph Node ExcisionLymph Node ExcisionLymph Node ExcisionLymph Node ExcisionLymph Node ExcisionLymph Node ExcisionLymph Nodes pathologyLymph Nodes pathologyLymph Nodes pathologyLymph Nodes pathologyLymph Nodes pathologyLymph Nodes pathologyLymph Nodes pathologyLymph Nodes surgeryLymph Nodes surgeryLymph Nodes surgeryLymph Nodes surgeryLymph Nodes surgeryLymph Nodes surgeryLymph Nodes surgeryLymphatic MetastasisLymphatic MetastasisLymphatic MetastasisLymphatic MetastasisLymphatic MetastasisLymphatic MetastasisLymphatic MetastasisMiddle AgedMiddle AgedMiddle AgedMiddle AgedMiddle AgedMiddle AgedMiddle AgedNeoplasm Recurrence, LocalNeoplasm Recurrence, LocalNeoplasm Recurrence, LocalNeoplasm Recurrence, LocalNeoplasm Recurrence, LocalNeoplasm Recurrence, LocalNeoplasm Recurrence, LocalNeoplasm StagingNeoplasm StagingNeoplasm StagingNeoplasm StagingNeoplasm StagingNeoplasm StagingNeoplasm StagingRetrospective StudiesRetrospective StudiesRetrospective StudiesRetrospective StudiesRetrospective StudiesRetrospective StudiesRetrospective StudiesNeoadjuvant TherapyNeoadjuvant TherapyNeoadjuvant TherapyNeoadjuvant TherapyNeoadjuvant TherapyNeoadjuvant TherapyNeoadjuvant TherapySentinel Lymph Node BiopsySentinel Lymph Node BiopsySentinel Lymph Node BiopsySentinel Lymph Node BiopsySentinel Lymph Node BiopsySentinel Lymph Node BiopsySentinel Lymph Node BiopsyLife Sciences Biochemistry, Genetics and Molecular Biology Cancer Research Breast Cancer Treatment StudiesHealth Sciences Medicine Surgery Breast Implant and ReconstructionHealth Sciences Medicine Pathology and Forensic Medicine Breast Lesions and CarcinomasImportance: Data on oncological outcomes after omission of axillary lymph node dissection (ALND) in patients with breast cancer that downstages from node positive to negative with neoadjuvant chemotherapy are sparse. Additionally, the best axillary surgical staging technique in this scenario is unknown. Objective: To investigate oncological outcomes after sentinel lymph node biopsy (SLNB) with dual-tracer mapping or targeted axillary dissection (TAD), which combines SLNB with localization and retrieval of the clipped lymph node. Design, Setting, and Participants: In this multicenter retrospective cohort study that was conducted at 25 centers in 11 countries, 1144 patients with consecutive stage II to III biopsy-proven node-positive breast cancer were included between April 2013 and December 2020. The cumulative incidence rates of axillary, locoregional, and any invasive (locoregional or distant) recurrence were determined by competing risk analysis. Exposure: Omission of ALND after SLNB or TAD. Main Outcomes and Measures: The primary end points were the 3-year and 5-year rates of any axillary recurrence. Secondary end points included locoregional recurrence, any invasive (locoregional and distant) recurrence, and the number of lymph nodes removed. Results: A total of 1144 patients (median [IQR] age, 50 [41-59] years; 78 [6.8%] Asian, 105 [9.2%] Black, 102 [8.9%] Hispanic, and 816 [71.0%] White individuals; 666 SLNB [58.2%] and 478 TAD [41.8%]) were included. A total of 1060 patients (93%) had N1 disease, 619 (54%) had ERBB2 (formerly HER2)-positive illness, and 758 (66%) had a breast pathologic complete response. TAD patients were more likely to receive nodal radiation therapy (85% vs 78%; P = .01). The clipped node was successfully retrieved in 97% of TAD cases and 86% of SLNB cases (without localization). The mean (SD) number of sentinel lymph nodes retrieved was 3 (2) vs 4 (2) (P < .001), and the mean (SD) number of total lymph nodes removed was 3.95 (1.97) vs 4.44 (2.04) (P < .001) in the TAD and SLNB groups, respectively. The 5-year rates of any axillary, locoregional, and any invasive recurrence in the entire cohort were 1.0% (95% CI, 0.49%-2.0%), 2.7% (95% CI, 1.6%-4.1%), and 10% (95% CI, 8.3%-13%), respectively. The 3-year cumulative incidence of axillary recurrence did not differ between TAD and SLNB (0.5% vs 0.8%; P = .55). Conclusions and Relevance: The results of this cohort study showed that axillary recurrence was rare in this setting and was not significantly lower after TAD vs SLNB. These results support omission of ALND in this population.Articlehttps://pubmed.ncbi.nlm.nih.gov/38662396https://opus.bibliothek.uni-augsburg.de/opus4/files/116881/116881.pdfhttps://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/11688110.1001/jamaoncol.2024.0578https://hdl.handle.net/20.500.15037/1183W4395466551enJAMA Oncology2374-24372374-24452024-04-252026-06-13T09:49:13Z2026-06-13T09:49:13Z |
| spellingShingle | Medicine Axillary Lymph Node Dissection Breast cancer Sentinel lymph node Biopsy Axilla Neoadjuvant therapy Retrospective cohort study Stage (stratigraphy) Surgery Dissection (medical) Lymph node Radiology Cancer Internal medicine Biology Paleontology Medicine Axillary Lymph Node Dissection Breast cancer Sentinel lymph node Biopsy Axilla Neoadjuvant therapy Retrospective cohort study Stage (stratigraphy) Surgery Dissection (medical) Lymph node Radiology Cancer Internal medicine Adult Adult Adult Adult Adult Adult Adult Aged Aged Aged Aged Aged Aged Aged Axilla Axilla Axilla Axilla Axilla Axilla Axilla Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Female Female Female Female Female Female Female Humans Humans Humans Humans Humans Humans Humans Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research Breast Cancer Treatment Studies Health Sciences Medicine Surgery Breast Implant and Reconstruction Health Sciences Medicine Pathology and Forensic Medicine Breast Lesions and Carcinomas Giacomo Montagna Mary M. Mrdutt Susie X. Sun Callie Hlavin Emilia J. Diego Stephanie M. Wong Andrea V. Barrio Astrid Botty van den Bruele Neslihan Cabıoğlu Varadan Sevilimedu Laura H. Rosenberger E. Shelley Hwang Abigail Ingham Bärbel Papassotiropoulos Bich Doan Nguyen-Sträuli Christian Kurzeder Danilo Díaz Aybar Denise Vorburger Dieter Michael Matlac Edvin Ostapenko Fabian Riedel Florian Fitzal Francesco Meani Franziska Fick Jacqueline Sagasser Jörg Heil Hasan Karanlık Konstantin J. Dedes László Romics Maggie Banys‐Paluchowski Mahmut Müslümanoğlu María del Rosario Cueva Pérez Marcelo Chávez Díaz Martin Heidinger Mathias K. Fehr Mattea Reinisch Mustafa Tükenmez Nadia Maggi Nicola Rocco Nina Ditsch Oreste Gentilini Régis Resende Paulinelli Sebastián Solé Zarhi Sherko Küemmel S. Bruz̆as Simona Di Lascio Tamara K. Parissenti Tanya L. Hoskin Uwe Güth Valentina Ovalle Christoph Tausch Henry M. Kuerer Abigail S. Caudle Jean-François Boileau Judy C. Boughey Thorsten Kühn Monica Morrow William P. Weber Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy |
| title | Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy |
| title_full | Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy |
| title_fullStr | Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy |
| title_full_unstemmed | Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy |
| title_short | Omission of Axillary Dissection Following Nodal Downstaging With Neoadjuvant Chemotherapy |
| title_sort | omission of axillary dissection following nodal downstaging with neoadjuvant chemotherapy |
| topic | Medicine Axillary Lymph Node Dissection Breast cancer Sentinel lymph node Biopsy Axilla Neoadjuvant therapy Retrospective cohort study Stage (stratigraphy) Surgery Dissection (medical) Lymph node Radiology Cancer Internal medicine Biology Paleontology Medicine Axillary Lymph Node Dissection Breast cancer Sentinel lymph node Biopsy Axilla Neoadjuvant therapy Retrospective cohort study Stage (stratigraphy) Surgery Dissection (medical) Lymph node Radiology Cancer Internal medicine Adult Adult Adult Adult Adult Adult Adult Aged Aged Aged Aged Aged Aged Aged Axilla Axilla Axilla Axilla Axilla Axilla Axilla Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Female Female Female Female Female Female Female Humans Humans Humans Humans Humans Humans Humans Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research Breast Cancer Treatment Studies Health Sciences Medicine Surgery Breast Implant and Reconstruction Health Sciences Medicine Pathology and Forensic Medicine Breast Lesions and Carcinomas |
| topic_facet | Medicine Axillary Lymph Node Dissection Breast cancer Sentinel lymph node Biopsy Axilla Neoadjuvant therapy Retrospective cohort study Stage (stratigraphy) Surgery Dissection (medical) Lymph node Radiology Cancer Internal medicine Biology Paleontology Medicine Axillary Lymph Node Dissection Breast cancer Sentinel lymph node Biopsy Axilla Neoadjuvant therapy Retrospective cohort study Stage (stratigraphy) Surgery Dissection (medical) Lymph node Radiology Cancer Internal medicine Adult Adult Adult Adult Adult Adult Adult Aged Aged Aged Aged Aged Aged Aged Axilla Axilla Axilla Axilla Axilla Axilla Axilla Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms drug therapy Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms pathology Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms surgery Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Breast Neoplasms therapy Female Female Female Female Female Female Female Humans Humans Humans Humans Humans Humans Humans Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Node Excision Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes pathology Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymph Nodes surgery Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Lymphatic Metastasis Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Middle Aged Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Recurrence, Local Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Neoplasm Staging Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Retrospective Studies Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Neoadjuvant Therapy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Sentinel Lymph Node Biopsy Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research Breast Cancer Treatment Studies Health Sciences Medicine Surgery Breast Implant and Reconstruction Health Sciences Medicine Pathology and Forensic Medicine Breast Lesions and Carcinomas |
| url | https://pubmed.ncbi.nlm.nih.gov/38662396 https://opus.bibliothek.uni-augsburg.de/opus4/files/116881/116881.pdf https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/116881 https://hdl.handle.net/20.500.15037/1183 |
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