Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas
OBJECTIVES.: To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease. MATERIAL AND METHODS: . Observational, descriptive and transversal st...
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2017
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| author | Pool Marcos-Carbajal Maribel Huaringa Nancy Rojas Victoria Gutiérrez Sila Ruiton Emelda Gallardo Jorge Achata Marco Galarza |
| author_browse | Emelda Gallardo Jorge Achata Marco Galarza Maribel Huaringa Nancy Rojas Pool Marcos-Carbajal Sila Ruiton Victoria Gutiérrez |
| author_facet | Pool Marcos-Carbajal Maribel Huaringa Nancy Rojas Victoria Gutiérrez Sila Ruiton Emelda Gallardo Jorge Achata Marco Galarza |
| author_sort | Pool Marcos-Carbajal |
| collection | Producción científica |
| description | OBJECTIVES.: To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease. MATERIAL AND METHODS: . Observational, descriptive and transversal study. We reviewed the clinical histories and laboratory tests of patients diagnosed with EB treated in INSN from 1993 to 2015. RESULTS.: 93 patients were registered. The average age was 7.9 ± 5.6 years; 53.8% (n = 50) were boys. Clinical forms corresponded to dystrophic EB with 41 (44.1%) cases, simple EB with 39 (41.9%) union EB cases with 8 (8.6%) and Kindler syndrome with 4 (4.3%) cases. The clinical form could not be identified in a case. A total of 48 cases (51.6%) came from Lima and Callao, and 45 cases (48.4%) from other provinces of the country. Extracutaneous manifestations involved gastrointestinal (44.1%), ocular (37.6%), odontogenic (87.1%), and nutritional (79.6%) involvement, as well as pseudosindactilia (16.1%). Chronic malnutrition (71.6%), acute malnutrition (17.6%) and anemia (62.4%) were found. Mortality corresponded to 6 cases (6.5%). CONCLUSIONS.: 93 cases of EB were reported in INSN, the predominant clinical presentation was the dystrophic form. |
| format | Article |
| id | oai:cris.upeu.edu.pe:20.500.15037/1153 |
| institution | UPeU |
| language | Spanish |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | oai:cris.upeu.edu.pe:20.500.15037/11532026-10-30T16:15:16ZDetección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicasPool Marcos-CarbajalMaribel HuaringaNancy RojasVictoria GutiérrezSila RuitonEmelda GallardoJorge AchataMarco GalarzaMedicineMalnutritionEpidemiologyInternal medicineDermatologyEpidermolysis bullosaPediatricsGastroenterologyMedicineMalnutritionEpidemiologyInternal medicineDermatologyEpidermolysis bullosaPediatricsGastroenterologyAdolescentAdolescentAdolescentCross-Sectional StudiesCross-Sectional StudiesCross-Sectional StudiesFemaleFemaleFemaleHumansHumansHumansInfluenza, Human virologyInfluenza, Human virologyInfluenza, Human virologyMaleMaleMaleHaemophilus influenzae type b isolation & purificationHaemophilus influenzae type b isolation & purificationHaemophilus influenzae type b isolation & purificationInfluenza A Virus, H1N1 Subtype isolation & purificationInfluenza A Virus, H1N1 Subtype isolation & purificationInfluenza A Virus, H1N1 Subtype isolation & purificationInfluenza A Virus, H3N2 Subtype isolation & purificationInfluenza A Virus, H3N2 Subtype isolation & purificationInfluenza A Virus, H3N2 Subtype isolation & purificationReal-Time Polymerase Chain ReactionReal-Time Polymerase Chain ReactionReal-Time Polymerase Chain ReactionLife Sciences Immunology and Microbiology Virology Poxvirus research and outbreaksLife Sciences Biochemistry, Genetics and Molecular Biology Cell Biology Skin and Cellular Biology ResearchHealth Sciences Medicine Physiology Syphilis Diagnosis and TreatmentOBJECTIVES.: To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease. MATERIAL AND METHODS: . Observational, descriptive and transversal study. We reviewed the clinical histories and laboratory tests of patients diagnosed with EB treated in INSN from 1993 to 2015. RESULTS.: 93 patients were registered. The average age was 7.9 ± 5.6 years; 53.8% (n = 50) were boys. Clinical forms corresponded to dystrophic EB with 41 (44.1%) cases, simple EB with 39 (41.9%) union EB cases with 8 (8.6%) and Kindler syndrome with 4 (4.3%) cases. The clinical form could not be identified in a case. A total of 48 cases (51.6%) came from Lima and Callao, and 45 cases (48.4%) from other provinces of the country. Extracutaneous manifestations involved gastrointestinal (44.1%), ocular (37.6%), odontogenic (87.1%), and nutritional (79.6%) involvement, as well as pseudosindactilia (16.1%). Chronic malnutrition (71.6%), acute malnutrition (17.6%) and anemia (62.4%) were found. Mortality corresponded to 6 cases (6.5%). CONCLUSIONS.: 93 cases of EB were reported in INSN, the predominant clinical presentation was the dystrophic form.Articlehttps://pubmed.ncbi.nlm.nih.gov/29177376https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/2054/2726https://doi.org/10.17843/rpmesp.2017.342.205410.17843/rpmesp.2017.342.2054https://hdl.handle.net/20.500.15037/1153W2728322388esRevista Peruana de Medicina Experimental y Salud Pública1726-46341726-46422017-06-302026-06-13T09:47:48Z2026-06-13T09:47:48Z |
| spellingShingle | Medicine Malnutrition Epidemiology Internal medicine Dermatology Epidermolysis bullosa Pediatrics Gastroenterology Medicine Malnutrition Epidemiology Internal medicine Dermatology Epidermolysis bullosa Pediatrics Gastroenterology Adolescent Adolescent Adolescent Cross-Sectional Studies Cross-Sectional Studies Cross-Sectional Studies Female Female Female Humans Humans Humans Influenza, Human virology Influenza, Human virology Influenza, Human virology Male Male Male Haemophilus influenzae type b isolation & purification Haemophilus influenzae type b isolation & purification Haemophilus influenzae type b isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Life Sciences Immunology and Microbiology Virology Poxvirus research and outbreaks Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology Skin and Cellular Biology Research Health Sciences Medicine Physiology Syphilis Diagnosis and Treatment Pool Marcos-Carbajal Maribel Huaringa Nancy Rojas Victoria Gutiérrez Sila Ruiton Emelda Gallardo Jorge Achata Marco Galarza Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas |
| title | Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas |
| title_full | Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas |
| title_fullStr | Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas |
| title_full_unstemmed | Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas |
| title_short | Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas |
| title_sort | deteccion de virus influenza a b y subtipos a h1n1 pdm09 a h3n2 por multiple rt pcr en muestras clinicas |
| topic | Medicine Malnutrition Epidemiology Internal medicine Dermatology Epidermolysis bullosa Pediatrics Gastroenterology Medicine Malnutrition Epidemiology Internal medicine Dermatology Epidermolysis bullosa Pediatrics Gastroenterology Adolescent Adolescent Adolescent Cross-Sectional Studies Cross-Sectional Studies Cross-Sectional Studies Female Female Female Humans Humans Humans Influenza, Human virology Influenza, Human virology Influenza, Human virology Male Male Male Haemophilus influenzae type b isolation & purification Haemophilus influenzae type b isolation & purification Haemophilus influenzae type b isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Life Sciences Immunology and Microbiology Virology Poxvirus research and outbreaks Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology Skin and Cellular Biology Research Health Sciences Medicine Physiology Syphilis Diagnosis and Treatment |
| topic_facet | Medicine Malnutrition Epidemiology Internal medicine Dermatology Epidermolysis bullosa Pediatrics Gastroenterology Medicine Malnutrition Epidemiology Internal medicine Dermatology Epidermolysis bullosa Pediatrics Gastroenterology Adolescent Adolescent Adolescent Cross-Sectional Studies Cross-Sectional Studies Cross-Sectional Studies Female Female Female Humans Humans Humans Influenza, Human virology Influenza, Human virology Influenza, Human virology Male Male Male Haemophilus influenzae type b isolation & purification Haemophilus influenzae type b isolation & purification Haemophilus influenzae type b isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H1N1 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Influenza A Virus, H3N2 Subtype isolation & purification Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Life Sciences Immunology and Microbiology Virology Poxvirus research and outbreaks Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology Skin and Cellular Biology Research Health Sciences Medicine Physiology Syphilis Diagnosis and Treatment |
| url | https://pubmed.ncbi.nlm.nih.gov/29177376 https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/2054/2726 https://doi.org/10.17843/rpmesp.2017.342.2054 https://hdl.handle.net/20.500.15037/1153 |
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