Caracterización microbiológica y molecular de la resistencia antimicrobiana de Escherichia coli uropatógenas de hospitales públicos peruanos

We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the...

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Autores principales: Marcos Carbajal, Pool, Salvatierra, Guillermo, Yareta Yareta, José Luis, Pino, Jimena, Vásquez, Nancy, Diaz, Pilar, Martínez, Isabel, Asmat, Percy, Peralta, Carlos, Huamani, Caridad, Briones, Alexander, Ruiz, Manuel, Laura, Nicomedes, Luque, Álvaro, Arapa, Leonel, Tsukayama, Pablo
Formato: Artículo
Lenguaje:español
Publicado: 2021
Materias:
escherichia coli
farmacorresistencia bacteriana
resistencia betalactámica
enfermedades urológicas
perú
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Sumario:We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the detection of the bla TEM, bla CTX-M, bla SHV and bla PER genes. The 65.7% (46/70) of the isolates presented a multidrug-resistant phenotype and 55.7% (39/70) were extended-spectrum beta-lactamases producers. High levels of resistance were detected for ampicillin (77,1%), ciprofloxacin (74,3%), trimethoprim/sulfamethoxazole (62,9%), cefepime (57,1%), and cefuroxime (57,1%). The bla TEM gene was the most frequent (31,4%), followed by bla CTX-M (18,6%) and bla SHV (2,9%) genes. These results show high resistance levels to antimicrobials of clinical use in E. coli isolates from hospital UTI patients in Peru.

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