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Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study por RenalTube Group, Alejandro García‐Castaño, Gustavo Pérez de Nanclares, Leire Madariaga, Mireia Aguirre, Sara Chocrón, A. Madrid, Francisco Javier Lafita Tejedor, Mercedes Gil‐Campos, Jaime Sánchez del Pozo, Rafael Ruiz Cano, Mar Espino, José María Gómez Vida, Fernando Santos, Víctor Manuel García Nieto, Reyner Loza, Luis Miguel Espinosa Rodríguez, Emilia Hidalgo Barquero, Nikoleta Printza, Juan Antonio Camacho, Luís Castaño, Gema Ariceta

“…Further, in one female patient, AVPR2 gene study turned out to be negative and she was found to be homozygous for the novel AQP2 p.Ala86Val alteration. Conclusion: Genetic analysis presumably confirmed the diagnosis of nephrogenic diabetes insipidus in every patient of the studied cohort. …”
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Early-Phase Perceptions of COVID-19’s Impact on Ophthalmology Practice Patterns: A Survey from the Pan-American Association of Ophthalmology por Francisco J. Bonilla‐Escobar, Daniel Sánchez-Cano, Andrés F. Lasave, Jaime Soria, Valentina Franco-Cárdenas, Víctor E. Reviglio, Paulo E.C. Dantas, Claudia Palacio-Pastrana, Juan Carlos Corbera, Rita Chan, Alberto Velzi Díaz, Milton Garcia Hernandez, Maurício Maia, Cristián Carpentier, Lihteh Wu, Martín Sánchez, Marcelo Murillo Sasamoto, Gonzalo Murillo Azcárraga, Jose Roca, Martín Serrano, Arturo Alezzandrini, Juan Sanchez Montoya, Gregorio Gabela, Gerardo García‐Aguirre, J. Fernando Arévalo

“…We aimed to assess the perceptions about the pandemic from countries' ophthalmological national and subspecialty retina societies affiliated to the Pan-American Association of Ophthalmology (PAAO). …”
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Increasing tree size across Amazonia por Adriane Esquivel‐Muelbert, Rebecca Banbury Morgan, Roel Brienen, Emanuel Gloor, Simon L. Lewis, Kyle G. Dexter, Everton Almeida, Edmar Almeida de Oliveira, Esteban Álvarez‐Dávila, Atila Alves de Oliveira, Ana Andrade, Simone Aparecida Vieira, Luiz E. O. C. Aragão, Alejandro Araujo‐Murakami, E.J.M.M. Arets, Luzmila Arroyo, Gerardo Aymard-Corredor, Olaf Bánki, Plínio Barbosa de Camargo, Jorcely Barroso, Lilian Blanc, Foster Brown, José Luís Camargo, Wendeson Castro, Víctor Chama Moscoso, Jérôme Chave, Ezequiel Chavez, James A. Comiskey, Antônio C. L. da Costa, Jhon del Águila Pasquel, Géraldine Derroire, Anthony Di Fiore, Sophie Fauset, Ted R. Feldpausch, Gerardo Flores Llampazo, René Guillén Villaroel, Rafael Herrera, Niro Higuchi, Eurídice Honorio Coronado, Isau Huamantupa‐Chuquimaco, Walter Huaraca Huasco, E. Jiménez, Timothy J. Killeen, Susan G. W. Laurance, William F. Laurance, Aurora Levesley, Gabriela Lopez-Gonzalez, Yadvinder Malhi, Beatriz Schwantes Marimon, Ben Hur Marimon Junior, Simone Matias Reis, Casimiro Mendoza Bautista, Irina Polo, Abel Monteagudo Mendoza, Paulo Sérgio Morandi, Adriano Nogueira Lima, Percy Núñez Vargas, Nadir Pallqui Camacho, Alexander Parada Gutierrez, Julie Peacock, María Cristina Peñuela-Mora, Georgia Pickavance, John Pipoly, Nigel C. A. Pitman, Adriana Prieto, Carlos Quesada, Freddy Ramírez Arévalo, Maxime Réjou-Méchain, Zorayda Restrepo Correa, Rocio Rojas, Lily O. Rodríguez, Anand Roopsind, Rafael Paiva Salomão, Natalino Silva, Javier Silva Espejo, Marcos Silveira, Juliana Stropp, Joey Talbot, Hans ter Steege, John Terborgh, Raquel Thomas, Luis Valenzuela Gamarra, Peter van der Hout, Rodolfo Vásquez, Ima Célia Guimarães Vieira, Emilio Vilanova, Roderick Zagt, Timothy R. Baker, Oliver L. Phillips

Materias: “…Range (aeronautics)…”
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Short-term association between hot nights and mortality: a multicountry analysis in 178 locations considering hourly ambient temperature por Dominic Royé, Francesco Sera, Aurelio Tobı́as, Masahiro Hashizume, Yasushi Honda, Ho Kim, Ana Maria Vicedo-Cabrera, Shilu Tong, Éric Lavigne, Jan Kyselý, Mathilde Pascal, Francesca de’Donato, Susana das Neves Pereira da Silva, Joana Madureira, Veronika Huber, Aleš Urban, Joel Schwartz, Michelle L. Bell, Ben Armstrong, Carmen Íñiguez, Rosana Abrutzky, Micheline de Sousa Zanotti Stagliorio Coêlho, Paulo Hilario Nascimento Saldiva, Patricia Matus Correa, Nicolás Valdés Ortega, Haidong Kan, Samuel Osorio, Antonio Gasparrini, Souzana Achilleos, Hans Orru, Ene Indermitte, Niilo Ryti, Alexandra Schneider, Klea Katsouyanni, Antonis Analitis, Fatemeh Mayvaneh, Alireza Enteyari, Raanan Raz, Paola Michelozzi, Yoonhee Kim, Barrak Alahmad, John Paul Cauchi, Magali Hurtado‐Díaz, Eunice Elizabeth Félix Arellano, Ala Overcenco, Jochem O. Klompmaker, Gabriel Carrasco, Xerxes Seposo, Paul Lester Chua, Iulian‐Horia Holobâcă, Yuming Guo, Jouni J. K. Jaakkola, Noah Scovronick, Fiorella Acquaotta, Whanhee Lee, Bertil Forsberg, Martina S. Ragettli, Shanshan Li, Antonella Zanobetti, Valentina Colistro, Trần Ngọc Đăng, Do Van Dung

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Rainfall events and daily mortality across 645 global locations: two stage time series analysis por Cheng He, Susanne Breitner-Busch, Veronika Huber, Kai Chen, Siqi Zhang, Antonio Gasparrini, Michelle L. Bell, Haidong Kan, Dominic Royé, Ben Armstrong, Joel Schwartz, Francesco Sera, Ana Maria Vicedo-Cabrera, Yasushi Honda, Jouni J K Jaakkola, Niilo Ryti, Jan Kyselý, Yuming Guo, Shilu Tong, Francesca de’Donato, Paola Michelozzi, Micheline de Sousa Zanotti Stagliorio Coêlho, Paulo Hilario Nascimento Saldiva, Eric Lavigne, Hans Orru, Ene Indermitte, Mathilde Pascal, Patrick Goodman, Ariana Zeka, Yoonhee Kim, Magali Hurtado‐Díaz, Eunice Elizabeth Félix Arellano, Ala Overcenco, Jochem O. Klompmaker, Shilpa Rao, Alfonso Diz-Lois Palomares, Gabriel Carrasco‐Escobar, Xerxes Seposo, Susana das Neves Pereira da Silva, Joana Madureira, Iulian‐Horia Holobâcă, Noah Scovronick, Fiorella Acquaotta, Ho Kim, Whanhee Lee, Masahiro Hashizume, Aurelio Tobı́as, Carmen Íñiguez, Bertil Forsberg, Martina S. Ragettli, Yue Leon Guo, Shih‐Chun Pan, Samuel Osorio, Shanshan Li, Antonella Zanobetti, Trần Ngọc Đăng, Do Van Dung, Alexandra Schneider

“…OBJECTIVE: To examine the associations between characteristics of daily rainfall (intensity, duration, and frequency) and all cause, cardiovascular, and respiratory mortality. …”
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Associations of ambient exposure to benzene, toluene, ethylbenzene, and xylene with daily mortality: a multicountry time-series study in 757 global locations por Lu Zhou, Xiong Ying, Francesco Sera, Ana Maria Vicedo-Cabrera, Rosana Abrutzky, Yuming Guo, Shilu Tong, Micheline de Sousa Zanotti Stagliorio Coêlho, Paulo Hilario Nascimento Saldiva, Éric Lavigne, Patricia Matus Correa, Nicolás Valdés Ortega, Samuel Osorio, Dominic Royé, Jan Kyselý, Hans Orru, Marek Maasikmets, Jouni J. K. Jaakkola, Niilo Ryti, Mathilde Pascal, Veronika Huber, Susanne Breitner-Busch, Alexandra Schneider, Klea Katsouyanni, Evangelia Samoli, Alireza Entezari, Fatemeh Mayvaneh, Patrick Goodman, Ariana Zeka, Raanan Raz, Matteo Scortichini, Massimo Stafoggia, Yasushi Honda, Masahiro Hashizume, Chris Fook Sheng Ng, Barrak Alahmad, Magali Hurtado‐Díaz, Eunice Elizabeth Félix Arellano, Ala Overcenco, Jochem O. Klompmaker, Shilpa Rao, Gabriel Carrasco‐Escobar, Xerxes Seposo, Paul Lester Chua, Susana Pereira Silva, Joana Madureira, Iulian‐Horia Holobâcă, Noah Scovronick, Rebecca M. Garland, Ho Kim, Whanhee Lee, Aurelio Tobı́as, Carmen Íñiguez, Bertil Forsberg, Martina S. Ragettli, Yue Leon Guo, Shih‐Chun Pan, Shanshan Li, Pierre Masselot, Valentina Colistro, Michelle L. Bell, Antonella Zanobetti, Joel Schwartz, Trần Ngọc Đăng, Do Van Dung, Antonio Gasparrini, Yaoxian Huang, Haidong Kan

“…Data on individual chemicals (ie, benzene, toluene, xylenes [summation of ethylbenzene, m-xylene, p-xylene, and o-xylene]) and the aggregate mixture (ie, BTEX) were estimated using a chemistry-climate model.We examined the short-term associations of each individual chemical as well as the BTEX mixture with daily total, cardiovascular, and respiratory mortality in a multicountry framework.Using a two-stage time-series design, we first applied generalised additive models with a quasi-Poisson distribution to obtain location-specific associations, which were subsequently pooled using random-effects meta-analysis.Two-pollutant models were used to assess the independent effects of BTEX after adjusting for co-pollutants (PM 25 , PM 10 , nitrogen dioxide, sulphur dioxide, ozone, and carbon monoxide).Additionally, we assessed the overall exposure-response curves with spline terms.Findings An IQR increment of BTEX concentration on lag 0-2 days (3-day moving average of the present day and the previous 2 days) was associated with increases of 057% (95% CI 049-065), 042% (030-054), and 068% (050-086) in total, cardiovascular, and respiratory mortality, respectively.The corresponding effect estimates for an IQR increment in individual chemicals (benzene, toluene, and xylenes) were 038-061%, 044-070%, and 041-065%, respectively.The associations remained significant after adjusting for co-pollutants, with a general decline in magnitude, except for a slight increase after adjustment for ozone.The shape of the exposureresponse curves for all pollutants and causes of death was almost linear, with steeper slopes at low concentrations and no discernible thresholds.Interpretation This global study provides novel evidence linking short-term exposure to ambient BTEX, both individually and as a mixture, with increased daily total, cardiovascular, and respiratory mortality.Our findings underscore the need for comprehensive air pollution mitigation policies, including stringent controls on BTEX emissions, to protect public health.…”
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Temperature frequency and mortality: Assessing adaptation to local temperature por Yao Wu, Bo Wen, Antonio Gasparrini, Ben Armstrong, Francesco Sera, Éric Lavigne, Shanshan Li, Yuming Guo, Ala Overcenco, Aleš Urban, Alexandra Schneider, Alireza Entezari, Ana María Vicedo-Cabrera, Antonella Zanobetti, Antonis Analitis, Ariana Zeka, Aurelio Tobı́as, Baltazar Nunes, Barrak Alahmad, Bertil Forsberg, Carmen Íñiguez, Caroline Ameling, César De la Cruz Valencia, Danny Houthuijs, Do Van Dung, Dominic Royé, Ene Indermitte, Fatemeh Mayvaneh, Fiorella Acquaotta, Francesca de’Donato, Gabriel Carrasco‐Escobar, Haidong Kan, Hanne Krage Carlsen, Hans Orru, Ho Kim, Iulian‐Horia Holobâcă, Jan Kyselý, Joana Madureira, Joel Schwartz, Jouni J. K. Jaakkola, Klea Katsouyanni, Magali Hurtado‐Díaz, Martina S. Ragettli, Masahiro Hashizume, Mathilde Pascal, Micheline de Sousa Zanotti Stagliorio Coêlho, Nicolás Valdés Ortega, Niilo Ryti, Noah Scovronick, Paola Michelozzi, Patricia Matus Correa, Patrick Goodman, Paulo Hilário Nascimento Saldiva, Raanan Raz, Rosana Abrutzky, Samuel Osorio, Shih‐Chun Pan, Shilpa Rao, Shilu Tong, Souzana Achilleos, Trần Ngọc Đăng, Valentina Colistro, Veronika Huber, Whanhee Lee, Xerxes Seposo, Yasushi Honda, Yoonhee Kim, Yue Leon Guo, Shanshan Li, Yuming Guo

“…Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. …”
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Comparison for the effects of different components of temperature variability on mortality: A multi-country time-series study por Bo Wen, Yao Wu, Yuming Guo, Antonio Gasparrini, Shilu Tong, Ala Overcenco, Aleš Urban, Alexandra Schneider, Alireza Entezari, Ana M. Vicedo‐Cabrera, Antonella Zanobetti, Antonis Analitis, Ariana Zeka, Aurelio Tobı́as, Baltazar Nunes, Barrak Alahmad, Ben Armstrong, Bertil Forsberg, Shih‐Chun Pan, Carmen Íñiguez, Caroline Ameling, César De la Cruz Valencia, Christofer Åström, Danny Houthuijs, Do Van Dung, Dominic Royé, Ene Indermitte, Éric Lavigne, Fatemeh Mayvaneh, Fiorella Acquaotta, Francesca de’Donato, Shilpa Rao, Francesco Sera, Gabriel Carrasco‐Escobar, Haidong Kan, Hans Orru, Ho Kim, Iulian‐Horia Holobâcă, Jan Kyselý, Joana Madureira, Joel Schwartz, Jouni J. K. Jaakkola, Klea Katsouyanni, Magali Hurtado‐Díaz, Martina S. Ragettli, Masahiro Hashizume, Mathilde Pascal, Micheline de Sousa Zanotti Stagliorio Coêlho, Nicolás Valdés Ortega, Niilo Ryti, Noah Scovronick, Paola Michelozzi, Patricia Matus Correa, Patrick Goodman, Paulo Hilário Nascimento Saldiva, Raanan Raz, Rosana Abrutzky, Samuel Osorio, Trần Ngọc Đăng, Valentina Colistro, Veronika Huber, Whanhee Lee, Xerxes Seposo, Yasushi Honda, Yoonhee Kim, Yue Leon Guo, Michelle L. Bell, Shanshan Li

“…We aimed to assess the association of intra-day TV and inter-day TV with all-cause, cardiovascular, and respiratory mortality. …”
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Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer por Alessandro Audisio, Chiara Gallio, Vaneja Velenik, Hélène Meillat, Erika Ruíz‐García, María Carmen Riesco Martínez, Javier Suárez Alecha, Gertjan Rasschaert, Carlos Carvalho, Violaine Randrian, Iva Kirac, Jorge Hernando, Mehmet Artaç, Juan Manuel O’Connor, Ithai Waldhorn, Pètra M. Braam, Ali Shamseddine, Roberto Moretto, Carolina de la Pinta, Francesca De Felice, Audrius Dulskas, D. Páez López-Bravo, Alexander Vanden Bulcke, Felix Bock, Amélie Deleporte, Marc Van den Eynde, Karen Geboes, Mauro Loi, Marco Messina, Constance Houlzé-Laroye, Alberto Puccini, Alessandro Pastorino, Demetris Papamichael, Michele Fiore, Daniel Sur, Michal Eid, Claire Antoun, Massimiliano Salati, Ingrid Garajová, Matas Jakubauskas, Jiří Tomášek, Cidália Pinto, Jérôme Schwingel, Federica Morano, Richard Adams, Alexandre Dermine, Amélie Chau, Ahsan Javed, Michele Ghidini, Francesco Fiorica, Paola Montenegro, Angelica Petrillo, Gaya Spolverato, N. Mulet Margalef, Marie Diaz, Chiara Baratelli, Francesco Puleo, Athanasios Karampeazis, Fatma Sert, Quentin Gilliaux, Alfonso De Stefano, Gabriel Liberale, Luigi Moretti, Philippe Martinive, Vaiva Deltuvaite Thomas, Vincent S. Staggs, Everardo D. Saad, Jean-Luc Van Laethem, Francesco Sclafani, Nada Benhima, Irene Assaf, Gianluca Ricco, Roberta Fazio, Fatima-Zahra Abbassi, Giacomo Bregni, Ana Veron, María Gómez Galdón, Maria Antonietta Bali, Ernestas Sileika, Edita Baltruškevičienė, Laura Miceviciute, Laudy Chehade, Annamaria Pessino, Chiara Pirrone, Greta Catani, Ana Fortuna, David Tougeron, Valentina Daprà, Michela Bartolini, María Alsina, Oğuzhan Yıldız, Maria E. Gallego, A.C. Virgili Manrique, M. Carmen Martínez, Josep Balart, Juan Carlos Pernas, Berta Martín-Cullell, Edith A. Fernández-Figueroa, Rogelio Cuervo-Campos, Antonio Moreno-Avendaño, Laura Galeani, Geneviève Van Ooteghem, Astrid De Cuyper, Christopthe Remue, R Bachmann, Daniel Léonard, Anca Dragean, Marie-Laure Castella, Paméla Baldin, Valeria Pavese, Beatrice Borelli, Elvira Rampello, Carlos Orlando Salsaña Reyes, Jennifer Aoun, Mariana Figueiredo, Martina Manni, Christos Cortas, Martina Benincasa, Marius Kryžauskas, Tomas Poškus, Carlo Messina, Nuno Couto, Ana Clara, Catarina Freitas, Joaquim Gago, G. Atalaia, S Soares Brandao, José Azevedo, Laura M. Fernández, Pedro Vieira, Hugo Domingos, Oriol Parés, Miguel Borges, Bernd Frerker, Francesco Celotto, Eva Pape, Gabriëlle H. van Ramshorst, Jhanzeb Ihsan, Victoria Shallcross, Shakil Ahmed, José María Fernández Cebrián, Ana Ferrer‐Gomez, E. Canales Lachén, Raquel García Latorre, Íñigo Martínez Delfrade, Beatriz Peñas García, M. Martín, B. Frutos, B.I. Morón, Reyes Ferreiro, Sofía Parejo, Juan Carlos García‐Ruiz, Pedro Abadía, Javier Díe Trill, Elena Mendía, Juan Ocaña Jiménez, E Tobaruela, Araceli Ballestero Pérez, Gloria M. Rodriguez, S. Sancho, André D’Hoore, Albert Wolthuis, Gabriele Bislenghi, Karin Haustermans, Sabine Tejpar, Filip Van Herpe, Jeroen Dekervel, Eric Van Cutsem, Raphaëla C. Dresen, Xavier Sagaert, Gert De Hertogh, Philippe Leclercq, Lynn Debrun, M. Amin Dalia, Andrea Modrego, Guillaume Piessen

Materias: “…Health Sciences Medicine Surgery Colorectal and Anal Carcinomas…”
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